ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4)

Gene: ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4) Canis lupus familiaris

Analyze

Symbol:

ENPP4

Name:

ectonucleotide pyrophosphatase/phosphodiesterase 4

RGD ID:

12083994

Description:

ENCODES a protein that exhibits bis(5'-adenosyl)-triphosphatase activity (inferred); INVOLVED IN blood coagulation (inferred); hemostasis (inferred); positive regulation of blood coagulation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

bis(5'-adenosyl)-triphosphatase ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function); ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative); ectonucleotide pyrophosphatase/phosphodiesterase family member 4

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	14,353,355 - 14,366,506 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	14,353,282 - 14,365,952 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	14,385,537 - 14,400,943 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	14,853,731 - 14,869,158 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	14,853,677 - 14,869,136 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	14,369,849 - 14,385,351 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	14,458,027 - 14,471,937 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	14,554,506 - 14,568,452 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood coagulation (IEA)

hemostasis (IEA)

positive regulation of blood coagulation (IEA)

purine ribonucleoside catabolic process (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

bis(5'-adenosyl)-triphosphatase activity (IEA)

protein binding (ISO)

References

Genomics

Comparative Map Data

ENPP4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	14,353,355 - 14,366,506 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	14,353,282 - 14,365,952 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	14,385,537 - 14,400,943 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	14,853,731 - 14,869,158 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	14,853,677 - 14,869,136 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	14,369,849 - 14,385,351 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	14,458,027 - 14,471,937 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	14,554,506 - 14,568,452 (+)	NCBI		UU_Cfam_GSD_1.0

ENPP4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	46,129,989 - 46,146,688 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	46,129,989 - 46,146,688 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	46,097,726 - 46,114,425 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	46,205,871 - 46,222,237 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	46,205,870 - 46,222,237	NCBI
Celera	6	47,650,241 - 47,666,973 (+)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	45,820,747 - 45,837,481 (+)	NCBI		HuRef
CHM1_1	6	46,100,957 - 46,117,681 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	45,965,077 - 45,981,776 (+)	NCBI		T2T-CHM13v2.0

Enpp4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	44,407,198 - 44,416,725 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	44,407,199 - 44,416,700 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	44,096,307 - 44,105,809 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	44,096,308 - 44,105,809 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	44,233,258 - 44,242,757 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	43,559,364 - 43,568,863 (-)	NCBI		MGSCv36	mm8
Celera	17	47,517,799 - 47,527,273 (-)	NCBI		Celera
Cytogenetic Map	17	B3	NCBI
cM Map	17	20.34	NCBI

Enpp4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	24,386,351 - 24,396,248 (+)	NCBI		GRCr8
mRatBN7.2	9	16,888,923 - 16,898,860 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	16,887,739 - 16,898,860 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	25,473,036 - 25,482,764 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	30,547,557 - 30,557,287 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	28,836,767 - 28,846,497 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	19,446,807 - 19,457,946 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	19,448,269 - 19,457,946 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	18,325,162 - 18,336,443 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	12,552,834 - 12,562,511 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	12,549,935 - 12,556,776 (+)	NCBI
Celera	9	14,615,372 - 14,625,059 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

Enpp4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	11,169,778 - 11,188,156 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	11,169,778 - 11,187,544 (+)	NCBI	ChiLan1.0	ChiLan1.0

ENPP4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	60,622,918 - 60,639,785 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	56,488,983 - 56,505,599 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	45,710,507 - 45,727,215 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	46,984,395 - 47,001,251 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	46,984,395 - 47,001,251 (+)	Ensembl	panpan1.1		panPan2

Enpp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	49,756,158 - 49,771,879 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	14,191,479 - 14,195,618 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	14,188,328 - 14,204,063 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ENPP4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	40,896,470 - 40,912,426 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	40,896,392 - 40,913,609 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	47,160,730 - 47,171,612 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ENPP4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	26,102,687 - 26,117,142 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	26,102,510 - 26,117,080 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	46,140,497 - 46,154,975 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Enpp4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	14,305,062 - 14,312,018 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	14,302,709 - 14,316,914 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ENPP4
158 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	4	3	16		4				12		10	6
Low	1	2	6	6	2	6	6	6		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014118485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014118486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038491974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038491975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038554235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038554236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038618103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038618104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000003193 ⟹ ENSCAFP00000002967

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	14,353,282 - 14,365,952 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845022630 ⟹ ENSCAFP00845017753

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	14,853,677 - 14,869,136 (+)	Ensembl

RefSeq Acc Id:

XM_014118485 ⟹ XP_013973960

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	14,353,355 - 14,366,506 (+)	NCBI
Dog10K_Boxer_Tasha	12	14,385,537 - 14,400,943 (+)	NCBI

Sequence:

show sequence

GGTCCTCGGGGCGGAGGGGCTGCTAACCGCGGCGCGGGGCGGGCGGGCCGCTACTGCGCAGGCG
CCGCAGGAAGGTCTCGGCTCGCGCGTGTCCCTTGGGGTCGGCTGGCCCCGCGGTTCACGAGCGC
CGAGGTCCGCGCCGGCCGCAGCTGGAACCCTGATTGCTTTCCTTCAACACATTCATTATGAAGT
TACTAGTAATACTTTTATTTTCTGGACTTATAACTGGTTATAGAGGTAACTCTTCCCATAGCTT
GCCATCCAAGTTACTACTGGTGTCCTTTGATGGTTTCAGAGCTGACTATCTACAGGACTATGAA
TTTCCTCATCTCCAGAATTTTATCAAAGAAGGAGTCCTGGTAGAGCATGTTAAAAATGTTTTTA
TCACAAAAACATTTCCAAACCACTACAGTATTGTGACAGGCTTGTATGAAGAAAGCCATGGCAT
CGTGGCTAATTCCATGTATGATGCAAGCACAAAGAAACGTTTTTCTGACTTTGATGACAAGGAT
CCTTTTTGGTGGAATGAAGCAGAACCTATTTGGGTGACCAACCAGCTTCAGGAAAACAGATCAA
GTGCTGCTGCTATGTGGCCTGGCACTGATGTACCCATTCACAATACCACACCTTCCTATTTTAT
GAATTATAGCTCTTCAGTGTCATTTGAGGAGAGACTAAATAACATTACCATGTGGCTGATGAAT
TCGAACCCACCGGTCACTTTTGCAACACTTTACTGGGAAGAACCAGATGCAAGTGGCCACAAAT
ACGGACCTGAAGATAAAGAAAACATGTACAGAGTGTTGAAAGGAATAGATGATCTCATTGGTGA
GCTAGTCCACAGACTCAAGGTGCTAGGATTGTGGGAAAATCTCAACGTGATCATTACAAGTGAT
CATGGGATGACCCAGTGCTCAAAGGAGAGACTGATAAACTTGGATCTCTGCATTGATAATTCAA
GCTACACTCTTGTAGATTTGACTCCAGTTGCTGCCCTACTTCCCAAGATAAATATCACGGAGGT
TTATAACAAACTGAAAGTCTGTGACCCTCACATGAACGTTTATCTCAAAGAAGAGATTCCTGCC
AGATTTCATTACCAACATAATGATCGAATTCAGCCTATTATTTTGGTTGCTGATGAAGGCTGGA
CAATTGTGTTAAATAAATCATTATCAAAATTAGGTGACCATGGCTATGATAATTCTTTGTCTAG
TATGCATCCATTTCTAGCTGCCCACGGTCCTGCATTTCACAAAGGCTACAAACAAAGCACAATT
AACAGTGTGGATATTTATCCAATGATGTGCCACATCCTGGGATTAAAACCACATCCCAATAATG
GAACCTTTGGTCATACGAAGTGTTTGTTAGTTGACCAGTGGTGCATTAATCTCCCAGAAGCCAT
CGGAATTGTTATTGGTGCGCTCTTGGTCTTAACCACACTAACATGCCTCATAATAATCATGCAG
AATAGACTGTCTGTACCCCGTCCATTTTCCCGACTTCAGCTGCAAGAAGATGACGATGATCCTT
TAATTGAGTAACATGCTGGAGTTTATACGGAATATCTTTGATTAGTCACAAAACCAAGGATACA
CTCAAAAAATGGTGTTCTAAGGATGAAAAATATACCTTGAAAGACAAAAAACTTAGACTAAGCA
TGCTAGAATTACTTTGTTTTTCCTTGTGCTTTGTTTTGGTGTATCAGCTAATTAACAAAAAACC
CTGACCATAGTAAAAATTTCTAGTAAGTCAACATAAACTATTTCTCTAACTAGAAACTTTAAGA
AAAATGATTGCCTCTGGTTTTTTTTGCTATGAAGATGACACATTTTTAAATAAAAATCTACCAA
AATTTAGTAGGCATGCTTTTCTAATAAATTTTTATATTTGTAACTGAAACAACAGAAATCTTTA
TGCAATTAGTGGATTTTGGATTTTGTGTATCAGGAAGGAAAAGTTTTCTATATTTTTATATTTC
ATGACTTTAATAGAGTTTGTATCCCAAGTAAACCTGTGACATAGGAAGACCTCTGTGGTGGTTA
ATAAAATTGGTTATCCAGGCAGAACAGATCTAGCATAGGAAGAAATTATTTTA

hide sequence

RefSeq Acc Id:

XM_014118486 ⟹ XP_013973961

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	14,353,767 - 14,366,506 (+)	NCBI
Dog10K_Boxer_Tasha	12	14,385,964 - 14,400,943 (+)	NCBI

Sequence:

show sequence

ACGGATTTCCTAGAAAACCAGAAAGCGAAGATGACCCTTTAGGTGCTTTTGATTGGCTGGACAG
CGCGCGAAGCACATGCTGCCCCTCTCGGCGTAGCTACCCCGTGGGGTAAGAGTGTCCCCATTCT
GCAGATGCGGAAACTGAGGCTCAGACAGGAACCCTGATTGCTTTCCTTCAACACATTCATTATG
AAGTTACTAGTAATACTTTTATTTTCTGGACTTATAACTGGTTATAGAGGTAACTCTTCCCATA
GCTTGCCATCCAAGTTACTACTGGTGTCCTTTGATGGTTTCAGAGCTGACTATCTACAGGACTA
TGAATTTCCTCATCTCCAGAATTTTATCAAAGAAGGAGTCCTGGTAGAGCATGTTAAAAATGTT
TTTATCACAAAAACATTTCCAAACCACTACAGTATTGTGACAGGCTTGTATGAAGAAAGCCATG
GCATCGTGGCTAATTCCATGTATGATGCAAGCACAAAGAAACGTTTTTCTGACTTTGATGACAA
GGATCCTTTTTGGTGGAATGAAGCAGAACCTATTTGGGTGACCAACCAGCTTCAGGAAAACAGA
TCAAGTGCTGCTGCTATGTGGCCTGGCACTGATGTACCCATTCACAATACCACACCTTCCTATT
TTATGAATTATAGCTCTTCAGTGTCATTTGAGGAGAGACTAAATAACATTACCATGTGGCTGAT
GAATTCGAACCCACCGGTCACTTTTGCAACACTTTACTGGGAAGAACCAGATGCAAGTGGCCAC
AAATACGGACCTGAAGATAAAGAAAACATGTACAGAGTGTTGAAAGGAATAGATGATCTCATTG
GTGAGCTAGTCCACAGACTCAAGGTGCTAGGATTGTGGGAAAATCTCAACGTGATCATTACAAG
TGATCATGGGATGACCCAGTGCTCAAAGGAGAGACTGATAAACTTGGATCTCTGCATTGATAAT
TCAAGCTACACTCTTGTAGATTTGACTCCAGTTGCTGCCCTACTTCCCAAGATAAATATCACGG
AGGTTTATAACAAACTGAAAGTCTGTGACCCTCACATGAACGTTTATCTCAAAGAAGAGATTCC
TGCCAGATTTCATTACCAACATAATGATCGAATTCAGCCTATTATTTTGGTTGCTGATGAAGGC
TGGACAATTGTGTTAAATAAATCATTATCAAAATTAGGTGACCATGGCTATGATAATTCTTTGT
CTAGTATGCATCCATTTCTAGCTGCCCACGGTCCTGCATTTCACAAAGGCTACAAACAAAGCAC
AATTAACAGTGTGGATATTTATCCAATGATGTGCCACATCCTGGGATTAAAACCACATCCCAAT
AATGGAACCTTTGGTCATACGAAGTGTTTGTTAGTTGACCAGTGGTGCATTAATCTCCCAGAAG
CCATCGGAATTGTTATTGGTGCGCTCTTGGTCTTAACCACACTAACATGCCTCATAATAATCAT
GCAGAATAGACTGTCTGTACCCCGTCCATTTTCCCGACTTCAGCTGCAAGAAGATGACGATGAT
CCTTTAATTGAGTAACATGCTGGAGTTTATACGGAATATCTTTGATTAGTCACAAAACCAAGGA
TACACTCAAAAAATGGTGTTCTAAGGATGAAAAATATACCTTGAAAGACAAAAAACTTAGACTA
AGCATGCTAGAATTACTTTGTTTTTCCTTGTGCTTTGTTTTGGTGTATCAGCTAATTAACAAAA
AACCCTGACCATAGTAAAAATTTCTAGTAAGTCAACATAAACTATTTCTCTAACTAGAAACTTT
AAGAAAAATGATTGCCTCTGGTTTTTTTTGCTATGAAGATGACACATTTTTAAATAAAAATCTA
CCAAAATTTAGTAGGCATGCTTTTCTAATAAATTTTTATATTTGTAACTGAAACAACAGAAATC
TTTATGCAATTAGTGGATTTTGGATTTTGTGTATCAGGAAGGAAAAGTTTTCTATATTTTTATA
TTTCATGACTTTAATAGAGTTTGTATCCCAAGTAAACCTGTGACATAGGAAGACCTCTGTGGTG
GTTAATAAAATTGGTTATCCAGGCAGAACAGATCTAGCATAGGAAGAAATTATTTTA

hide sequence

RefSeq Acc Id:

XM_038491974 ⟹ XP_038347902

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	14,369,849 - 14,385,351 (+)	NCBI

RefSeq Acc Id:

XM_038491975 ⟹ XP_038347903

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	14,370,276 - 14,385,351 (+)	NCBI

RefSeq Acc Id:

XM_038554235 ⟹ XP_038410163

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	14,554,506 - 14,568,452 (+)	NCBI

RefSeq Acc Id:

XM_038554236 ⟹ XP_038410164

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	14,554,933 - 14,568,452 (+)	NCBI

RefSeq Acc Id:

XM_038618103 ⟹ XP_038474031

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	14,458,027 - 14,471,937 (+)	NCBI

RefSeq Acc Id:

XM_038618104 ⟹ XP_038474032

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	14,458,455 - 14,471,937 (+)	NCBI

RefSeq Acc Id:

XM_038683691 ⟹ XP_038539619

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	14,853,731 - 14,869,158 (+)	NCBI

RefSeq Acc Id:

XM_038683692 ⟹ XP_038539620

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	14,854,158 - 14,869,158 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013973960	(Get FASTA)	NCBI Sequence Viewer
	XP_013973961	(Get FASTA)	NCBI Sequence Viewer
	XP_038347902	(Get FASTA)	NCBI Sequence Viewer
	XP_038347903	(Get FASTA)	NCBI Sequence Viewer
	XP_038410163	(Get FASTA)	NCBI Sequence Viewer
	XP_038410164	(Get FASTA)	NCBI Sequence Viewer
	XP_038474031	(Get FASTA)	NCBI Sequence Viewer
	XP_038474032	(Get FASTA)	NCBI Sequence Viewer
	XP_038539619	(Get FASTA)	NCBI Sequence Viewer
	XP_038539620	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000002967.3
	ENSCAFP00030011045.1
	ENSCAFP00040020300.1
	ENSCAFP00845017753
	ENSCAFP00845017753.1

RefSeq Acc Id:

XP_013973960 ⟸ XM_014118485

- UniProtKB:

A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKLLVILLFSGLITGYRGNSSHSLPSKLLLVSFDGFRADYLQDYEFPHLQNFIKEGVLVEHVKN
VFITKTFPNHYSIVTGLYEESHGIVANSMYDASTKKRFSDFDDKDPFWWNEAEPIWVTNQLQEN
RSSAAAMWPGTDVPIHNTTPSYFMNYSSSVSFEERLNNITMWLMNSNPPVTFATLYWEEPDASG
HKYGPEDKENMYRVLKGIDDLIGELVHRLKVLGLWENLNVIITSDHGMTQCSKERLINLDLCID
NSSYTLVDLTPVAALLPKINITEVYNKLKVCDPHMNVYLKEEIPARFHYQHNDRIQPIILVADE
GWTIVLNKSLSKLGDHGYDNSLSSMHPFLAAHGPAFHKGYKQSTINSVDIYPMMCHILGLKPHP
NNGTFGHTKCLLVDQWCINLPEAIGIVIGALLVLTTLTCLIIIMQNRLSVPRPFSRLQLQEDDD
DPLIE

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RefSeq Acc Id:

XP_013973961 ⟸ XM_014118486

- UniProtKB:

A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKLLVILLFSGLITGYRGNSSHSLPSKLLLVSFDGFRADYLQDYEFPHLQNFIKEGVLVEHVKN
VFITKTFPNHYSIVTGLYEESHGIVANSMYDASTKKRFSDFDDKDPFWWNEAEPIWVTNQLQEN
RSSAAAMWPGTDVPIHNTTPSYFMNYSSSVSFEERLNNITMWLMNSNPPVTFATLYWEEPDASG
HKYGPEDKENMYRVLKGIDDLIGELVHRLKVLGLWENLNVIITSDHGMTQCSKERLINLDLCID
NSSYTLVDLTPVAALLPKINITEVYNKLKVCDPHMNVYLKEEIPARFHYQHNDRIQPIILVADE
GWTIVLNKSLSKLGDHGYDNSLSSMHPFLAAHGPAFHKGYKQSTINSVDIYPMMCHILGLKPHP
NNGTFGHTKCLLVDQWCINLPEAIGIVIGALLVLTTLTCLIIIMQNRLSVPRPFSRLQLQEDDD
DPLIE

hide sequence

RefSeq Acc Id:

ENSCAFP00000002967 ⟸ ENSCAFT00000003193

RefSeq Acc Id:

XP_038347902 ⟸ XM_038491974

RefSeq Acc Id:

XP_038347903 ⟸ XM_038491975

RefSeq Acc Id:

XP_038474031 ⟸ XM_038618103

RefSeq Acc Id:

XP_038474032 ⟸ XM_038618104

RefSeq Acc Id:	XP_038539619 ⟸ XM_038683691
- UniProtKB:	A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038539620 ⟸ XM_038683692
- UniProtKB:	A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038410163 ⟸ XM_038554235
- UniProtKB:	A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038410164 ⟸ XM_038554236
- UniProtKB:	A0A8C0MKF3 (UniProtKB/TrEMBL), A0A8C0R038 (UniProtKB/TrEMBL), A0A8I3NY55 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845017753 ⟸ ENSCAFT00845022630

Promoters

RGD ID:

13685449

Promoter ID:

EPDNEW_C3517

Type:

multiple initiation site

Name:

ENPP4_1

Description:

ectonucleotide pyrophosphatase/phosphodiesterase 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	14,353,414 - 14,353,474	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002020	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030006854	UniProtKB/TrEMBL
	ENSCAFG00040012687	UniProtKB/TrEMBL
	ENSCAFG00845012734	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000003193.5	UniProtKB/TrEMBL
	ENSCAFT00030012621.1	UniProtKB/TrEMBL
	ENSCAFT00040023392.1	UniProtKB/TrEMBL
	ENSCAFT00845022630	ENTREZGENE
	ENSCAFT00845022630.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1360.180	UniProtKB/TrEMBL
	3.40.720.10	UniProtKB/TrEMBL
InterPro	Alkaline_phosphatase_core_sf	UniProtKB/TrEMBL
	Phosphodiest/P_Trfase	UniProtKB/TrEMBL
KEGG Report	cfa:481823	UniProtKB/TrEMBL
NCBI Gene	ENPP4	ENTREZGENE
PANTHER	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE	UniProtKB/TrEMBL
	PTHR10151:SF79	UniProtKB/TrEMBL
Pfam	Phosphodiest	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53649	UniProtKB/TrEMBL
UniProt	A0A8C0MKF3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0R038	ENTREZGENE
	A0A8I3NY55	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:49603	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-09-26	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4		ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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