FBXO31 (F-box protein 31) - Rat Genome Database

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Gene: FBXO31 (F-box protein 31) Canis lupus familiaris
Analyze
Symbol: FBXO31
Name: F-box protein 31
RGD ID: 12083031
Description: ENCODES a protein that exhibits cyclin binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); DNA damage response (ortholog); mitotic G1 DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal recessive intellectual developmental disorder 45 (ortholog); congenital nongoitrous hypothyroidism 2 (ortholog); FOUND IN centrosome (ortholog); neuronal cell body (ortholog); SCF ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 31
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,703,591 - 65,734,956 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,703,575 - 65,731,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,701,948 - 65,746,369 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0565,912,307 - 65,956,714 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1565,936,368 - 65,980,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0565,768,645 - 65,813,053 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0566,182,624 - 66,227,196 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FBXO31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,703,591 - 65,734,956 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,703,575 - 65,731,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,701,948 - 65,746,369 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0565,912,307 - 65,956,714 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1565,936,368 - 65,980,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0565,768,645 - 65,813,053 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0566,182,624 - 66,227,196 (+)NCBIUU_Cfam_GSD_1.0
FBXO31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381687,326,987 - 87,392,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1687,326,987 - 87,392,142 (-)EnsemblGRCh38hg38GRCh38
GRCh371687,360,593 - 87,425,727 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,920,443 - 85,974,864 (-)NCBINCBI36Build 36hg18NCBI36
Build 341685,920,444 - 85,974,864NCBI
Celera1671,659,646 - 71,722,476 (-)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1673,106,044 - 73,168,796 (-)NCBIHuRef
CHM1_11688,774,754 - 88,837,518 (-)NCBICHM1_1
T2T-CHM13v2.01693,397,874 - 93,463,013 (-)NCBIT2T-CHM13v2.0
Fbxo31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,276,182 - 122,305,607 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8122,276,179 - 122,305,545 (-)EnsemblGRCm39 Ensembl
GRCm388121,549,443 - 121,578,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,549,440 - 121,578,806 (-)EnsemblGRCm38mm10GRCm38
MGSCv378124,075,879 - 124,102,706 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368124,437,993 - 124,464,843 (-)NCBIMGSCv36mm8
Celera8125,773,510 - 125,800,328 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.65NCBI
Fbxo31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,533,437 - 66,564,674 (-)NCBIGRCr8
mRatBN7.21949,624,813 - 49,656,052 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,627,686 - 49,656,010 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1956,418,500 - 56,446,780 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,102,655 - 57,130,983 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,317,009 - 59,345,307 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01953,487,610 - 53,625,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,487,613 - 53,625,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01964,224,819 - 64,363,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41951,836,918 - 51,837,223 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1948,874,360 - 48,902,812 (-)NCBICelera
Cytogenetic Map19q12NCBI
Fbxo31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555411,811,010 - 1,828,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555411,811,010 - 1,828,734 (-)NCBIChiLan1.0ChiLan1.0
FBXO31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21897,087,090 - 97,139,973 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116103,000,732 - 103,056,347 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01667,997,481 - 68,053,081 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11687,322,364 - 87,377,104 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1687,322,364 - 87,377,104 (-)Ensemblpanpan1.1panPan2
Fbxo31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934926,048,159 - 26,078,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,801,548 - 1,830,440 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,801,539 - 1,831,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,949,276 - 1,995,462 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,949,254 - 1,995,459 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.262,037,200 - 2,081,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1572,696,868 - 72,752,480 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl572,701,136 - 72,752,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660472,944,370 - 3,001,044 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247463,043,600 - 3,078,223 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247463,034,458 - 3,078,230 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FBXO31
316 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014113955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014113956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000031679   ⟹   ENSCAFP00000029493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl565,703,575 - 65,731,056 (+)Ensembl
RefSeq Acc Id: XM_038476927   ⟹   XP_038332855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1565,936,368 - 65,980,668 (+)NCBI
RefSeq Acc Id: XM_038476928   ⟹   XP_038332856
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1565,936,368 - 65,980,668 (+)NCBI
RefSeq Acc Id: XM_038525471   ⟹   XP_038381399
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha565,701,948 - 65,746,369 (+)NCBI
RefSeq Acc Id: XM_038525472   ⟹   XP_038381400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha565,701,948 - 65,746,369 (+)NCBI
RefSeq Acc Id: XM_038538098   ⟹   XP_038394026
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0566,182,624 - 66,227,196 (+)NCBI
RefSeq Acc Id: XM_038538099   ⟹   XP_038394027
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0566,182,624 - 66,227,196 (+)NCBI
RefSeq Acc Id: XM_038602221   ⟹   XP_038458149
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0565,768,645 - 65,813,053 (+)NCBI
RefSeq Acc Id: XM_038602222   ⟹   XP_038458150
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0565,768,645 - 65,813,053 (+)NCBI
RefSeq Acc Id: XM_038666838   ⟹   XP_038522766
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0565,912,307 - 65,956,714 (+)NCBI
RefSeq Acc Id: XM_038666839   ⟹   XP_038522767
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0565,912,307 - 65,956,714 (+)NCBI
Ensembl Acc Id: ENSCAFP00000029493   ⟸   ENSCAFT00000031679
RefSeq Acc Id: XP_038332855   ⟸   XM_038476927
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038332856   ⟸   XM_038476928
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458149   ⟸   XM_038602221
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458150   ⟸   XM_038602222
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038522766   ⟸   XM_038666838
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTZ8 (UniProtKB/TrEMBL),   A0A8C0SJY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038522767   ⟸   XM_038666839
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JS43 (UniProtKB/TrEMBL),   A0A8C0SIF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381399   ⟸   XM_038525471
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTZ8 (UniProtKB/TrEMBL),   A0A8C0SJY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381400   ⟸   XM_038525472
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JS43 (UniProtKB/TrEMBL),   A0A8C0SIF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394026   ⟸   XM_038538098
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTZ8 (UniProtKB/TrEMBL),   A0A8C0SJY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394027   ⟸   XM_038538099
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JS43 (UniProtKB/TrEMBL),   A0A8C0SIF3 (UniProtKB/TrEMBL)
Protein Domains
F-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019910 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040013531 UniProtKB/TrEMBL
  ENSCAFG00845004168 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031679.5 UniProtKB/TrEMBL
  ENSCAFT00000031681.6 UniProtKB/TrEMBL
  ENSCAFT00000094760.1 UniProtKB/TrEMBL
  ENSCAFT00000100818.1 UniProtKB/TrEMBL
  ENSCAFT00000104966.1 UniProtKB/TrEMBL
  ENSCAFT00000109356.1 UniProtKB/TrEMBL
  ENSCAFT00000109820.1 UniProtKB/TrEMBL
  ENSCAFT00040024997.1 UniProtKB/TrEMBL
  ENSCAFT00040025054.1 UniProtKB/TrEMBL
  ENSCAFT00040025172.1 UniProtKB/TrEMBL
  ENSCAFT00845007461.1 UniProtKB/TrEMBL
  ENSCAFT00845007470.1 UniProtKB/TrEMBL
  ENSCAFT00845007482.1 UniProtKB/TrEMBL
  ENSCAFT00845007497.1 UniProtKB/TrEMBL
  ENSCAFT00845007501.1 UniProtKB/TrEMBL
  ENSCAFT00845007510.1 UniProtKB/TrEMBL
  ENSCAFT00845007518.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
InterPro DUF4568 UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  FBXO31/39 UniProtKB/TrEMBL
NCBI Gene FBXO31 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 31 UniProtKB/TrEMBL
  PTHR10706 UniProtKB/TrEMBL
Pfam Cyclin_D1_bind UniProtKB/TrEMBL
  DUF4568 UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
UniProt A0A8C0JS43 ENTREZGENE
  A0A8C0JTZ8 ENTREZGENE
  A0A8C0SIF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SJY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YXR6_CANLF UniProtKB/TrEMBL
  A0A8I3MPD6_CANLF UniProtKB/TrEMBL
  A0A8I3MRF2_CANLF UniProtKB/TrEMBL
  A0A8I3MS26_CANLF UniProtKB/TrEMBL
  A0A8I3MS48_CANLF UniProtKB/TrEMBL
  A0A8I3MS59_CANLF UniProtKB/TrEMBL
  A0A8I3RRV7_CANLF UniProtKB/TrEMBL
  A0A8I3RRW1_CANLF UniProtKB/TrEMBL
  A0A8P0NKY2_CANLF UniProtKB/TrEMBL
  A0A8P0NL28_CANLF UniProtKB/TrEMBL
  A0A8P0PQN4_CANLF UniProtKB/TrEMBL
  A0A8P0PQN6_CANLF UniProtKB/TrEMBL
  A0A8P0PQU8_CANLF UniProtKB/TrEMBL
  A0A8P0TUK4_CANLF UniProtKB/TrEMBL
  A0A8P0TV71_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40773 ENTREZGENE