BCO1 (beta-carotene oxygenase 1) - Rat Genome Database

Name: BCO1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: BCO1 (beta-carotene oxygenase 1) Canis lupus familiaris

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Symbol:

BCO1

Name:

beta-carotene oxygenase 1

RGD ID:

12082325

Description:

ENCODES a protein that exhibits beta-carotene 15,15'-dioxygenase activity (ortholog); INVOLVED IN beta-carotene metabolic process (ortholog); retinal metabolic process (ortholog); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 1 (ortholog); familial cold autoinflammatory syndrome 3 (ortholog); giant axonal neuropathy 1 (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

BCMO1; beta,beta-carotene 15,15'-dioxygenase; beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BCO1 (beta-carotene oxygenase 1)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Bco1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Bco1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bco1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BCO1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bco1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BCO1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BCO1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bco1 (beta-carotene oxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	70,598,743 - 70,637,273 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	70,599,284 - 70,637,017 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	70,547,948 - 70,586,427 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	70,903,713 - 70,942,206 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	70,903,715 - 70,942,392 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	70,846,152 - 70,884,642 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	70,681,343 - 70,719,822 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	71,159,198 - 71,197,682 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 1 (ISO)

familial cold autoinflammatory syndrome 3 (ISO)

giant axonal neuropathy 1 (ISO)

Hypercarotenemia and Vitamin A Deficiency, Autosomal Dominant (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

beta-carotene metabolic process (IEA,ISO)

carotene catabolic process (IEA)

retinal metabolic process (IEA,ISO)

retinoid metabolic process (IEA)

Molecular Function

beta-carotene 15,15'-dioxygenase activity (IEA,ISO)

metal ion binding (IEA)

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

retinol metabolic pathway (ISO)

vitamin A deficiency pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

BCO1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	70,598,743 - 70,637,273 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	70,599,284 - 70,637,017 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	70,547,948 - 70,586,427 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	70,903,713 - 70,942,206 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	70,903,715 - 70,942,392 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	70,846,152 - 70,884,642 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	70,681,343 - 70,719,822 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	71,159,198 - 71,197,682 (-)	NCBI		UU_Cfam_GSD_1.0

BCO1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	81,238,689 - 81,291,142 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	81,238,689 - 81,291,142 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	81,272,294 - 81,324,747 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	79,829,797 - 79,882,248 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	79,829,796 - 79,882,248	NCBI
Celera	16	65,569,740 - 65,622,032 (+)	NCBI		Celera
Cytogenetic Map	16	q23.2	NCBI
HuRef	16	67,027,575 - 67,079,925 (+)	NCBI		HuRef
CHM1_1	16	82,683,655 - 82,736,052 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	87,299,473 - 87,351,905 (+)	NCBI		T2T-CHM13v2.0

Bco1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	117,822,590 - 117,860,459 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	117,822,593 - 117,860,459 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	117,095,851 - 117,133,720 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	117,095,854 - 117,133,720 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	119,619,765 - 119,657,620 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	119,981,842 - 120,019,458 (+)	NCBI		MGSCv36	mm8
Celera	8	121,315,369 - 121,353,295 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	63.61	NCBI

Bco1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	62,058,061 - 62,094,923 (+)	NCBI		GRCr8
mRatBN7.2	19	45,149,250 - 45,186,102 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	45,149,265 - 45,186,101 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	51,959,095 - 51,995,942 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	52,612,116 - 52,648,960 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	54,856,354 - 54,893,189 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	49,637,059 - 49,673,577 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	49,637,016 - 49,673,808 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	60,424,580 - 60,460,636 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	47,202,955 - 47,239,225 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	47,207,835 - 47,244,106 (+)	NCBI
Celera	19	44,421,345 - 44,457,802 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

Bco1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955522	3,985,266 - 4,018,886 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955522	3,985,515 - 4,018,116 (+)	NCBI	ChiLan1.0	ChiLan1.0

BCO1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	90,987,587 - 91,047,027 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	96,908,478 - 96,962,121 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	61,843,567 - 61,897,012 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	81,270,957 - 81,323,088 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	81,270,577 - 81,323,088 (+)	Ensembl	panpan1.1		panPan2

Bco1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	30,698,707 - 30,729,976 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	28,859,318 - 28,889,934 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	28,859,222 - 28,890,407 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCO1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	7,012,332 - 7,055,305 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	7,008,330 - 7,054,089 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

BCO1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	66,681,756 - 66,730,832 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	66,681,513 - 66,733,604 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	9,105,596 - 9,155,354 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bco1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	6,143,892 - 6,180,408 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	6,146,338 - 6,181,020 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in BCO1
439 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014113991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022419143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038477024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038477025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038538209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038538210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038602336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038602337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038666943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038666944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000031845 ⟹ ENSCAFP00000029650

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	70,599,284 - 70,637,017 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845035136 ⟹ ENSCAFP00845027503

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	70,903,715 - 70,942,392 (-)	Ensembl

RefSeq Acc Id:

XM_014113991 ⟹ XP_013969466

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	70,598,743 - 70,632,931 (-)	NCBI
Dog10K_Boxer_Tasha	5	70,547,948 - 70,579,548 (-)	NCBI

Sequence:

show sequence

CGGGCCTGGAATGCACACAGTGGGAGAGACCAGATACAACCATTGGTTCGATGGCCTGGCCTTG
CTCCATAGCTTCACAATCAGAGATGAGACTCCAGAGACAGGAGAACCAGCAGGGCATAACCAAG
CCATGGCTGTCTTGCAGAAGCATGGCTGCCATCCACCAAAAGCCTTGAGTGGGCTAAACAGGCA
CGTGACTAAAGTTATCCCACAGCGTTTAGACTTTCTGAAAGTCTCTAGAAGATTCTCAAACTAA
AAATTCATTGTCAAAGGTGAAGTTTATTACAGGAGCAAATACCTGAGAAGTGATACCTACAAAG
ACAACATCGAGGCCAACAGGATTGTGGTGTCAGAGTTTGGAACGATGGCCTACCCAGACCCCTG
CAAAAACATATTTTCTAAAGCTTTCTCCTACTTGTCCCATACCATCCCTGATTTCACAGACAAT
TGCCTGATTAACATCATGAAGTGTGGGGAAGACTTCTATGCGACCACAGAGACCAATTACATCA
GGAAAATCAACCCACATACTCTGGAAACCCTGGAGAAGGTTGATTATCGCAAGTTCGTGGCTGT
AAATCTGGCAACAGCACATCCTCATTATGATGAAGCTGGAAATGTTCTTAATATGGGCACGTCC
ATCATGGACAAGGGGAAGACAAAATATGTGATCTTTAAAATCCCTGCCACAGTCCCAGAGGACA
AGAAGGAGAAGAACCCCTTGAAGCACACGGAGGTGTTCTGCTCCATCACCTCCCGCTCCCTCCT
CTCCCCGAGCTATTACCACAGCTTCGGAGTCACGGAGAACTACGTCATTTTCCTCGAGCAGCCT
TTCAAGCTGGATATCCTCAAAATGTCAACTGCGTACATCCGGGGAGTGAACTGGGCTTCCTGCA
TGGCTTTCCACAAGGAAGACAAGACTTATATTCACATCATCGACCAAAGGACCAGGAAACCTGT
GCCCACCAAGTTTTACACGGACCCCATGGTGGTCTTTCATCACGTCAATGCCTACGAGGAGGAT
GGCTGCCTTCTCTTTGACGTCATTGCCTACGAGGACAGCAGCCTTTACCAGCTCTTCTACTTGG
CCAACCTGAACCAGGACTTTGAGGAGAACTCAAGGCTAACCTCCATCCCCACCCTCAGGAGGTT
TGCTGTGCCTCTCAATGTGGACAAGAATGCAGAGGTGGGCTCAAATCTAATCAAACTGGCATCT
ACAACAGCAAGAGCCCTGAAGGAAAAGGATGACCAAGTCTACTGCCAGCCGGAGTTGCTTTATG
AAGGTTTAGAGCTGCCTCGGATCAATTATGCTCACAATGGGAAGCGATACCGCTATATCTTTGC
TGCTGAAGTTCAGTGGAGTCCCATCCCAACCAAGATACTGAAATATGATGTTCTCACAAAGTCA
TCCTTAAAATGGGGACAGGAACACTGCTGGCCAGCAGAACCCCTGTTTGTACCCACACCGGGTG
CCAAGGACGAGGATGATGGGATTATCTTATCAGCCATCGTCTCTACTGATCCCCAAAAGCTGCC
TTTTCTACTTATTCTGGATGCCAAAAGTTTTACAGAATTAGCCCGTGCATCTATTGATGTAGAG
ATGCACCTGGATCTCCATGGGCTATTCATCCCGGACACAGACTGCAACACCGGGAAGCAGGCCC
CTTCCCAGGAAGAGCAGGACAGGGCTCCGGACTGCCACGCGGCCCCACAGATCTGACTGGGCTG
GGGCTTGGGCCCCTCCCTGGGAAGAAGGACTCCAGGCTTGCTTCTTCTCTGGGTGAAGGGGACA
TCCTTCATTTCGTTTTGCACTTATTCTTTCTGTGGTTGATTTGAGACGAAGGTATGGAAATAGT
GCTTGTCAGTATCTTTTCTTTCAACTTATTTTGGCCATAAAAACCTTGTTTAAAAGTGGATCAA
ATATTTATTGATTAGCTCAAGCACTTCTAAGAAAGCCTTTTTCCTTTATTATAATGACAATGAC
CAGAAATTGTATTAAGTCATATAATCATCCTTCTTAGAATAAGCAACCACTGACTTGTCAAAGA
AGAGACAAGTAAGTATTTTTCGCTGCTCCGTCCTGCCACCCCTTCTTTCCCTCTTTCCAGGAGA
CTAGACAGTGCATCTGAGAGTCCTAGCTTTCTCCACTGAGCCCTGTTAGTAAATTATGTGGCCA
GGAAGGCAGAGTGCTTTGTGGTCATTCCATGCAAGGCATGGCATGATATAAAATAATAAAAACT
TTAAAATCTGTTCCAACCTTA

hide sequence

RefSeq Acc Id:

XM_022419143 ⟹ XP_022274851

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	70,598,743 - 70,637,273 (-)	NCBI
Dog10K_Boxer_Tasha	5	70,547,948 - 70,586,427 (-)	NCBI

Sequence:

show sequence

GGACACAATAAGAGGGTTAAAGATTAGCCAGGACTCATGGCTGGGGAATTGACCTTTGACCACA
GATAAGTAACACCAGCTTCCCCTCGTGTGTGCAAAGAGATACCAGGTTCTCAGAGCATCAGGAG
GAGATGCAAGAGAAGGAAGCTGCAGGAGAGCAGGAAGGAAAAAAAAGGAGGAGCCGAAGAGCAA
TTGCCTTGAACACAGCAGAGTGTCTGTTCACTGTCAGCATCACTCCTGCTCAGCGCCCCATGCC
ATGGATATAATATTTGGCAGAAATAAGAAGGAGCAGCTGGAACCTGTGCGGGCCAAAGTGACAG
GCAGGATTCCAACATGGCTGCAGGGCACCCTGCTCCGTAACGGGCCTGGAATGCACACAGTGGG
AGAGACCAGATACAACCATTGGTTCGATGGCCTGGCCTTGCTCCATAGCTTCACAATCAGAGAT
GGTGAAGTTTATTACAGGAGCAAATACCTGAGAAGTGATACCTACAAAGACAACATCGAGGCCA
ACAGGATTGTGGTGTCAGAGTTTGGAACGATGGCCTACCCAGACCCCTGCAAAAACATATTTTC
TAAAGCTTTCTCCTACTTGTCCCATACCATCCCTGATTTCACAGACAATTGCCTGATTAACATC
ATGAAGTGTGGGGAAGACTTCTATGCGACCACAGAGACCAATTACATCAGGAAAATCAACCCAC
ATACTCTGGAAACCCTGGAGAAGGTTGATTATCGCAAGTTCGTGGCTGTAAATCTGGCAACAGC
ACATCCTCATTATGATGAAGCTGGAAATGTTCTTAATATGGGCACGTCCATCATGGACAAGGGG
AAGACAAAATATGTGATCTTTAAAATCCCTGCCACAGTCCCAGAGGACAAGAAGGAGAAGAACC
CCTTGAAGCACACGGAGGTGTTCTGCTCCATCACCTCCCGCTCCCTCCTCTCCCCGAGCTATTA
CCACAGCTTCGGAGTCACGGAGAACTACGTCATTTTCCTCGAGCAGCCTTTCAAGCTGGATATC
CTCAAAATGTCAACTGCGTACATCCGGGGAGTGAACTGGGCTTCCTGCATGGCTTTCCACAAGG
AAGACAAGACTTATATTCACATCATCGACCAAAGGACCAGGAAACCTGTGCCCACCAAGTTTTA
CACGGACCCCATGGTGGTCTTTCATCACGTCAATGCCTACGAGGAGGATGGCTGCCTTCTCTTT
GACGTCATTGCCTACGAGGACAGCAGCCTTTACCAGCTCTTCTACTTGGCCAACCTGAACCAGG
ACTTTGAGGAGAACTCAAGGCTAACCTCCATCCCCACCCTCAGGAGGTTTGCTGTGCCTCTCAA
TGTGGACAAGAATGCAGAGGTGGGCTCAAATCTAATCAAACTGGCATCTACAACAGCAAGAGCC
CTGAAGGAAAAGGATGACCAAGTCTACTGCCAGCCGGAGTTGCTTTATGAAGGTTTAGAGCTGC
CTCGGATCAATTATGCTCACAATGGGAAGCGATACCGCTATATCTTTGCTGCTGAAGTTCAGTG
GAGTCCCATCCCAACCAAGATACTGAAATATGATGTTCTCACAAAGTCATCCTTAAAATGGGGA
CAGGAACACTGCTGGCCAGCAGAACCCCTGTTTGTACCCACACCGGGTGCCAAGGACGAGGATG
ATGGGATTATCTTATCAGCCATCGTCTCTACTGATCCCCAAAAGCTGCCTTTTCTACTTATTCT
GGATGCCAAAAGTTTTACAGAATTAGCCCGTGCATCTATTGATGTAGAGATGCACCTGGATCTC
CATGGGCTATTCATCCCGGACACAGACTGCAACACCGGGAAGCAGGCCCCTTCCCAGGAAGAGC
AGGACAGGGCTCCGGACTGCCACGCGGCCCCACAGATCTGACTGGGCTGGGGCTTGGGCCCCTC
CCTGGGAAGAAGGACTCCAGGCTTGCTTCTTCTCTGGGTGAAGGGGACATCCTTCATTTCGTTT
TGCACTTATTCTTTCTGTGGTTGATTTGAGACGAAGGTATGGAAATAGTGCTTGTCAGTATCTT
TTCTTTCAACTTATTTTGGCCATAAAAACCTTGTTTAAAAGTGGATCAAATATTTATTGATTAG
CTCAAGCACTTCTAAGAAAGCCTTTTTCCTTTATTATAATGACAATGACCAGAAATTGTATTAA
GTCATATAATCATCCTTCTTAGAATAAGCAACCACTGACTTGTCAAAGAAGAGACAAGTAAGTA
TTTTTCGCTGCTCCGTCCTGCCACCCCTTCTTTCCCTCTTTCCAGGAGACTAGACAGTGCATCT
GAGAGTCCTAGCTTTCTCCACTGAGCCCTGTTAGTAAATTATGTGGCCAGGAAGGCAGAGTGCT
TTGTGGTCATTCCATGCAAGGCATGGCATGATATAAAATAATAAAAACTTTAAAATCTGTTCCA
ACCTTA

hide sequence

RefSeq Acc Id:

XM_038477024 ⟹ XP_038332952

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	70,846,152 - 70,884,642 (-)	NCBI

RefSeq Acc Id:

XM_038477025 ⟹ XP_038332953

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	70,846,152 - 70,877,763 (-)	NCBI

RefSeq Acc Id:

XM_038538209 ⟹ XP_038394137

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	71,159,198 - 71,197,682 (-)	NCBI

RefSeq Acc Id:

XM_038538210 ⟹ XP_038394138

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	71,159,198 - 71,190,803 (-)	NCBI

RefSeq Acc Id:

XM_038602336 ⟹ XP_038458264

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	70,681,343 - 70,719,822 (-)	NCBI

RefSeq Acc Id:

XM_038602337 ⟹ XP_038458265

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	70,681,343 - 70,712,943 (-)	NCBI

RefSeq Acc Id:

XM_038666943 ⟹ XP_038522871

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	70,903,713 - 70,942,206 (-)	NCBI

RefSeq Acc Id:

XM_038666944 ⟹ XP_038522872

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	70,903,713 - 70,935,325 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_013969466	(Get FASTA)	NCBI Sequence Viewer
	XP_022274851	(Get FASTA)	NCBI Sequence Viewer
	XP_038332952	(Get FASTA)	NCBI Sequence Viewer
	XP_038332953	(Get FASTA)	NCBI Sequence Viewer
	XP_038394137	(Get FASTA)	NCBI Sequence Viewer
	XP_038394138	(Get FASTA)	NCBI Sequence Viewer
	XP_038458264	(Get FASTA)	NCBI Sequence Viewer
	XP_038458265	(Get FASTA)	NCBI Sequence Viewer
	XP_038522871	(Get FASTA)	NCBI Sequence Viewer
	XP_038522872	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000029650.5
	ENSCAFP00000070403.1
	ENSCAFP00030002015.1
	ENSCAFP00040029753.1
	ENSCAFP00845027503
	ENSCAFP00845027503.1

RefSeq Acc Id:	XP_013969466 ⟸ XM_014113991
- Peptide Label:	isoform X2
- UniProtKB:	A0A8P0NL42 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAYPDPCKNIFSKAFSYLSHTIPDFTDNCLINIMKCGEDFYATTETNYIRKINPHTLETLEKVD YRKFVAVNLATAHPHYDEAGNVLNMGTSIMDKGKTKYVIFKIPATVPEDKKEKNPLKHTEVFCS ITSRSLLSPSYYHSFGVTENYVIFLEQPFKLDILKMSTAYIRGVNWASCMAFHKEDKTYIHIID QRTRKPVPTKFYTDPMVVFHHVNAYEEDGCLLFDVIAYEDSSLYQLFYLANLNQDFEENSRLTS IPTLRRFAVPLNVDKNAEVGSNLIKLASTTARALKEKDDQVYCQPELLYEGLELPRINYAHNGK RYRYIFAAEVQWSPIPTKILKYDVLTKSSLKWGQEHCWPAEPLFVPTPGAKDEDDGIILSAIVS TDPQKLPFLLILDAKSFTELARASIDVEMHLDLHGLFIPDTDCNTGKQAPSQEEQDRAPDCHAA PQI hide sequence

RefSeq Acc Id:	XP_022274851 ⟸ XM_022419143
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0T2J0 (UniProtKB/TrEMBL), A0A8I3PIC4 (UniProtKB/TrEMBL), A0A8P0NL42 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDIIFGRNKKEQLEPVRAKVTGRIPTWLQGTLLRNGPGMHTVGETRYNHWFDGLALLHSFTIRD GEVYYRSKYLRSDTYKDNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDFTDNCLINI MKCGEDFYATTETNYIRKINPHTLETLEKVDYRKFVAVNLATAHPHYDEAGNVLNMGTSIMDKG KTKYVIFKIPATVPEDKKEKNPLKHTEVFCSITSRSLLSPSYYHSFGVTENYVIFLEQPFKLDI LKMSTAYIRGVNWASCMAFHKEDKTYIHIIDQRTRKPVPTKFYTDPMVVFHHVNAYEEDGCLLF DVIAYEDSSLYQLFYLANLNQDFEENSRLTSIPTLRRFAVPLNVDKNAEVGSNLIKLASTTARA LKEKDDQVYCQPELLYEGLELPRINYAHNGKRYRYIFAAEVQWSPIPTKILKYDVLTKSSLKWG QEHCWPAEPLFVPTPGAKDEDDGIILSAIVSTDPQKLPFLLILDAKSFTELARASIDVEMHLDL HGLFIPDTDCNTGKQAPSQEEQDRAPDCHAAPQI hide sequence

Ensembl Acc Id:

ENSCAFP00000029650 ⟸ ENSCAFT00000031845

RefSeq Acc Id:	XP_038332952 ⟸ XM_038477024
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038332953 ⟸ XM_038477025
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038458264 ⟸ XM_038602336
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038458265 ⟸ XM_038602337
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038522871 ⟸ XM_038666943
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0T2J0 (UniProtKB/TrEMBL), A0A8I3PIC4 (UniProtKB/TrEMBL), A0A8P0NL42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038522872 ⟸ XM_038666944
- Peptide Label:	isoform X2
- UniProtKB:	A0A8P0NL42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038394137 ⟸ XM_038538209
- Peptide Label:	isoform X1
- UniProtKB:	A0A8P0NL42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038394138 ⟸ XM_038538210
- Peptide Label:	isoform X2
- UniProtKB:	A0A8P0NL42 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845027503 ⟸ ENSCAFT00845035136

Promoters

RGD ID:

13683412

Promoter ID:

EPDNEW_C1482

Type:

multiple initiation site

Name:

BCO1_1

Description:

beta-carotene oxygenase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	70,637,158 - 70,637,218	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000020006	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030001278	UniProtKB/TrEMBL
	ENSCAFG00040018455	UniProtKB/TrEMBL
	ENSCAFG00845019952	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000031845.5	UniProtKB/TrEMBL
	ENSCAFT00000106160.1	UniProtKB/TrEMBL
	ENSCAFT00030002276.1	UniProtKB/TrEMBL
	ENSCAFT00040034178.1	UniProtKB/TrEMBL
	ENSCAFT00845035136	ENTREZGENE
	ENSCAFT00845035136.1	UniProtKB/TrEMBL
InterPro	Carotenoid_Oase	UniProtKB/TrEMBL
NCBI Gene	BCO1	ENTREZGENE
PANTHER	BETA,BETA-CAROTENE 15,15'-DIOXYGENASE	UniProtKB/TrEMBL
	PTHR10543	UniProtKB/TrEMBL
Pfam	RPE65	UniProtKB/TrEMBL
UniProt	A0A8C0T2J0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PIC4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NL42	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:38417	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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