KBTBD13 (kelch repeat and BTB domain containing 13) - Rat Genome Database

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Gene: KBTBD13 (kelch repeat and BTB domain containing 13) Canis lupus familiaris
Analyze
Symbol: KBTBD13
Name: kelch repeat and BTB domain containing 13
RGD ID: 12082012
Description: ENCODES a protein that exhibits actin filament binding (inferred); INVOLVED IN actin filament organization (ortholog); regulation of the force of skeletal muscle contraction (ortholog); relaxation of skeletal muscle (ortholog); ASSOCIATED WITH Actin-Accumulation Myopathy (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch repeat and BTB (POZ) domain containing 13; kelch repeat and BTB domain-containing protein 13
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,455,261 - 29,458,757 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3029,455,566 - 29,456,945 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3029,385,353 - 29,388,658 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03029,644,568 - 29,647,873 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3029,644,809 - 29,646,188 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13029,577,292 - 29,580,596 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03029,638,960 - 29,642,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03029,879,855 - 29,883,160 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
KBTBD13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,455,261 - 29,458,757 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3029,455,566 - 29,456,945 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3029,385,353 - 29,388,658 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03029,644,568 - 29,647,873 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3029,644,809 - 29,646,188 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13029,577,292 - 29,580,596 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03029,638,960 - 29,642,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03029,879,855 - 29,883,160 (+)NCBIUU_Cfam_GSD_1.0
KBTBD13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381565,076,746 - 65,079,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1565,076,746 - 65,079,948 (+)EnsemblGRCh38hg38GRCh38
GRCh371565,369,084 - 65,372,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361563,156,207 - 63,157,583 (+)NCBINCBI36Build 36hg18NCBI36
Celera1542,247,313 - 42,250,435 (+)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1542,193,792 - 42,196,914 (+)NCBIHuRef
CHM1_11565,488,941 - 65,492,063 (+)NCBICHM1_1
T2T-CHM13v2.01562,886,164 - 62,889,366 (+)NCBIT2T-CHM13v2.0
Kbtbd13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39965,295,965 - 65,299,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl965,295,966 - 65,298,934 (-)EnsemblGRCm39 Ensembl
GRCm38965,388,684 - 65,391,652 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl965,388,684 - 65,391,652 (-)EnsemblGRCm38mm10GRCm38
MGSCv37965,236,491 - 65,239,459 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36965,186,690 - 65,189,658 (-)NCBIMGSCv36mm8
Celera962,618,597 - 62,621,565 (-)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.28NCBI
Kbtbd13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8874,804,981 - 74,806,718 (-)NCBIGRCr8
mRatBN7.2865,909,821 - 65,911,558 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_WKY_Bbb_1.0867,564,817 - 67,566,556 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0870,907,934 - 70,909,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0870,599,850 - 70,602,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4869,640,085 - 69,641,459 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera865,307,580 - 65,309,317 (-)NCBICelera
Cytogenetic Map8q24NCBI
Kbtbd13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545010,345,753 - 10,347,129 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545010,344,020 - 10,347,686 (-)NCBIChiLan1.0ChiLan1.0
KBTBD13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21654,322,677 - 54,326,747 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,494,250 - 58,498,321 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01544,016,331 - 44,019,797 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11562,300,878 - 62,303,991 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1562,300,878 - 62,302,254 (+)Ensemblpanpan1.1panPan2
Kbtbd13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640107,550,882 - 107,552,957 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647125,399,004 - 25,400,380 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647125,399,004 - 25,401,396 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KBTBD13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1163,113,324 - 163,116,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11163,113,280 - 163,116,889 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KBTBD13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,507,709 - 18,511,025 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,509,555 - 18,510,931 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048122,922,508 - 122,924,239 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kbtbd13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247817,418,856 - 7,425,396 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247817,420,012 - 7,425,396 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KBTBD13
41 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 3 1 6 2 4
Below cutoff 4 13 1 5 1 5 10 8 7 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000027123   ⟹   ENSCAFP00000046163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3029,455,566 - 29,456,945 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845043532   ⟹   ENSCAFP00845034105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3029,644,809 - 29,646,188 (+)Ensembl
RefSeq Acc Id: XM_005642487   ⟹   XP_005642544
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13029,455,261 - 29,458,757 (+)NCBI
Dog10K_Boxer_Tasha3029,385,353 - 29,388,658 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038441778   ⟹   XP_038297706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03029,644,568 - 29,647,873 (+)NCBI
RefSeq Acc Id: XM_038517551   ⟹   XP_038373479
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13029,577,292 - 29,580,596 (+)NCBI
RefSeq Acc Id: XM_038579883   ⟹   XP_038435811
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03029,879,855 - 29,883,160 (+)NCBI
RefSeq Acc Id: XM_038644138   ⟹   XP_038500066
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03029,638,960 - 29,642,265 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005642544   ⟸   XM_005642487
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TWG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000046163   ⟸   ENSCAFT00000027123
RefSeq Acc Id: XP_038373479   ⟸   XM_038517551
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038500066   ⟸   XM_038644138
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038297706   ⟸   XM_038441778
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TWG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038435811   ⟸   XM_038579883
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TWG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845034105   ⟸   ENSCAFT00845043532
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017125 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040025049 UniProtKB/TrEMBL
  ENSCAFG00845024657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027123.5 UniProtKB/TrEMBL
  ENSCAFT00040046695.1 UniProtKB/TrEMBL
  ENSCAFT00845043532 ENTREZGENE
  ENSCAFT00845043532.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.80 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene KBTBD13 ENTREZGENE
PANTHER KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13 UniProtKB/TrEMBL
  KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A8C0TWG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S4U2_CANLF UniProtKB/TrEMBL
  A0A8P0SZ50_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:111537 ENTREZGENE