EVC (EvC ciliary complex subunit 1) - Rat Genome Database

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Gene: EVC (EvC ciliary complex subunit 1) Canis lupus familiaris
Analyze
Symbol: EVC
Name: EvC ciliary complex subunit 1
RGD ID: 12081225
Description: INVOLVED IN cartilage development (ortholog); ASSOCIATED WITH Ellis-Van Creveld syndrome (ortholog); genetic disease (ortholog); nephronophthisis (ortholog); FOUND IN cell projection (inferred); ciliary basal body (inferred); ciliary membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ellis van Creveld syndrome
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1370,937,957 - 71,007,431 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl370,937,926 - 71,016,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha373,488,645 - 73,558,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0371,699,331 - 71,768,497 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,699,331 - 71,768,497 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1370,969,854 - 71,038,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,130,786 - 71,200,049 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,508,152 - 71,577,452 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EVC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1370,937,957 - 71,007,431 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl370,937,926 - 71,016,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha373,488,645 - 73,558,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0371,699,331 - 71,768,497 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,699,331 - 71,768,497 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1370,969,854 - 71,038,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,130,786 - 71,200,049 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,508,152 - 71,577,452 (+)NCBIUU_Cfam_GSD_1.0
EVC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3845,711,201 - 5,829,057 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl45,711,201 - 5,814,305 (+)EnsemblGRCh38hg38GRCh38
GRCh3745,712,928 - 5,816,032 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3645,763,825 - 5,866,932 (+)NCBINCBI36Build 36hg18NCBI36
Build 3445,830,995 - 5,934,103NCBI
Celera45,610,660 - 5,713,978 (+)NCBICelera
Cytogenetic Map4p16.2NCBI
HuRef45,648,399 - 5,751,953 (+)NCBIHuRef
CHM1_145,710,930 - 5,813,984 (+)NCBICHM1_1
T2T-CHM13v2.045,682,855 - 5,800,650 (+)NCBIT2T-CHM13v2.0
Evc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39537,446,314 - 37,495,489 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl537,446,442 - 37,494,238 (-)EnsemblGRCm39 Ensembl
GRCm38537,288,970 - 37,336,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl537,289,098 - 37,336,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv37537,690,410 - 37,728,120 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36537,587,422 - 37,625,110 (-)NCBIMGSCv36mm8
Celera534,748,894 - 34,787,541 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.06NCBI
Evc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81477,680,901 - 77,722,608 (+)NCBIGRCr8
mRatBN7.21473,456,181 - 73,498,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,456,222 - 73,498,099 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1477,901,822 - 77,941,920 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,142,670 - 79,182,768 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,587,290 - 75,627,338 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,213,601 - 78,253,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,213,635 - 78,253,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01478,187,667 - 78,227,302 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41479,020,120 - 79,060,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11479,034,502 - 79,040,894 (+)NCBI
Celera1472,408,984 - 72,448,907 (+)NCBICelera
Cytogenetic Map14q21NCBI
Evc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555144,279,073 - 4,331,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555144,279,603 - 4,330,897 (-)NCBIChiLan1.0ChiLan1.0
EVC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v235,975,357 - 6,098,852 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan145,908,343 - 6,023,859 (+)NCBINHGRI_mPanPan1
PanPan1.145,790,437 - 5,892,283 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl45,789,316 - 5,894,265 (+)Ensemblpanpan1.1panPan2
Evc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528564,239,100 - 64,295,647 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647717,937,677 - 17,993,727 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647717,940,792 - 17,992,996 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl84,810,093 - 4,891,165 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.184,808,622 - 4,891,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.282,327,527 - 2,352,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EVC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12741,853,475 - 41,944,584 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2741,861,918 - 41,944,333 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604788,647,349 - 88,739,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Evc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475522,437,167 - 22,478,591 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475522,432,174 - 22,478,595 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EVC
1015 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 1
Low 5 5 22 6 6 6 6 6 7 10 5
Below cutoff 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000024942   ⟹   ENSCAFP00000023143
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl370,937,926 - 71,016,115 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000063965   ⟹   ENSCAFP00000048171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl370,937,926 - 70,973,336 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000092673   ⟹   ENSCAFP00000047170
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl370,937,926 - 71,004,230 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845006492   ⟹   ENSCAFP00845005165
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl371,699,331 - 71,768,497 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845006533   ⟹   ENSCAFP00845005201
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl371,699,331 - 71,734,744 (+)Ensembl
RefSeq Acc Id: XM_005618584   ⟹   XP_005618641
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1370,937,957 - 71,007,431 (+)NCBI
Dog10K_Boxer_Tasha373,488,645 - 73,558,112 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038472429   ⟹   XP_038328357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1370,969,854 - 71,038,897 (+)NCBI
RefSeq Acc Id: XM_038533404   ⟹   XP_038389332
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0371,508,152 - 71,577,452 (+)NCBI
RefSeq Acc Id: XM_038533405   ⟹   XP_038389333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0371,508,152 - 71,577,452 (+)NCBI
RefSeq Acc Id: XM_038597711   ⟹   XP_038453639
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0371,130,786 - 71,200,049 (+)NCBI
RefSeq Acc Id: XM_038597712   ⟹   XP_038453640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0371,130,786 - 71,200,049 (+)NCBI
RefSeq Acc Id: XM_038661904   ⟹   XP_038517832
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0371,699,331 - 71,768,497 (+)NCBI
RefSeq Acc Id: XM_038661905   ⟹   XP_038517833
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0371,699,331 - 71,768,497 (+)NCBI
RefSeq Acc Id: XM_848809   ⟹   XP_853902
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1370,937,957 - 71,007,431 (+)NCBI
Dog10K_Boxer_Tasha373,488,645 - 73,558,112 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_853902   ⟸   XM_848809
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M013 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005618641   ⟸   XM_005618584
- Peptide Label: isoform X2
- UniProtKB: A0A8P0SJV6 (UniProtKB/TrEMBL),   A0A8C0M013 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000047170   ⟸   ENSCAFT00000092673
RefSeq Acc Id: ENSCAFP00000048171   ⟸   ENSCAFT00000063965
RefSeq Acc Id: ENSCAFP00000023143   ⟸   ENSCAFT00000024942
RefSeq Acc Id: XP_038328357   ⟸   XM_038472429
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453639   ⟸   XM_038597711
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453640   ⟸   XM_038597712
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038517832   ⟸   XM_038661904
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M013 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038517833   ⟸   XM_038661905
- Peptide Label: isoform X2
- UniProtKB: A0A8I3RT02 (UniProtKB/TrEMBL),   A0A8C0M013 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389332   ⟸   XM_038533404
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M013 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389333   ⟸   XM_038533405
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M013 (UniProtKB/TrEMBL),   A0A8P0SJV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845005165   ⟸   ENSCAFT00845006492
RefSeq Acc Id: ENSCAFP00845005201   ⟸   ENSCAFT00845006533

Promoters
RGD ID:13682824
Promoter ID:EPDNEW_C894
Type:initiation region
Name:EVC_1
Description:EvC ciliary complex subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1370,937,794 - 70,937,854EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015745 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001208 UniProtKB/TrEMBL
  ENSCAFG00845003606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024942.5 UniProtKB/TrEMBL
  ENSCAFT00000063965.2 UniProtKB/TrEMBL
  ENSCAFT00030002207.1 UniProtKB/TrEMBL
  ENSCAFT00030002222.1 UniProtKB/TrEMBL
  ENSCAFT00845006492 ENTREZGENE
  ENSCAFT00845006492.1 UniProtKB/TrEMBL
  ENSCAFT00845006533.1 UniProtKB/TrEMBL
InterPro Limbin/Ellis-van_Creveld UniProtKB/TrEMBL
NCBI Gene EVC ENTREZGENE
PANTHER PTHR16795 UniProtKB/TrEMBL
  PTHR16795:SF13 UniProtKB/TrEMBL
UniProt A0A8C0LUU1_CANLF UniProtKB/TrEMBL
  A0A8C0M013 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RT02 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RT09_CANLF UniProtKB/TrEMBL
  A0A8P0SJV6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0NYB2 UniProtKB/TrEMBL
VGNC ID VGNC:40503 ENTREZGENE