C35H6orf52 (chromosome 35 C6orf52 homolog)

Gene: C35H6orf52 (chromosome 35 C6orf52 homolog) Canis lupus familiaris

Analyze

Symbol:

C35H6orf52

Name:

chromosome 35 C6orf52 homolog

RGD ID:

12080432

Description:

ENCODES a protein that exhibits tRNA binding (inferred); INVOLVED IN selenocysteine incorporation (inferred); ASSOCIATED WITH cataract 13 with adult i phenotype (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

chromosome 35 open reading frame, human C6orf52; putative uncharacterized protein C6orf52 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	10,422,161 - 10,436,031 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	10,422,255 - 10,432,336 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	10,370,981 - 10,385,023 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	10,526,377 - 10,540,527 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	10,526,554 - 10,540,504 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	10,355,805 - 10,369,564 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	10,402,708 - 10,416,783 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	11,723,241 - 11,737,288 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cataract 13 with adult i phenotype (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

selenocysteine incorporation (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

tRNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

C35H6orf52
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	10,422,161 - 10,436,031 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	10,422,255 - 10,432,336 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	10,370,981 - 10,385,023 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	10,526,377 - 10,540,527 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	10,526,554 - 10,540,504 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	10,355,805 - 10,369,564 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	10,402,708 - 10,416,783 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	11,723,241 - 11,737,288 (-)	NCBI		UU_Cfam_GSD_1.0

C6orf52
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	10,671,422 - 10,694,891 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	10,671,418 - 10,694,797 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	10,671,655 - 10,695,030 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	10,779,637 - 10,795,769 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	6	11,900,143 - 11,923,522 (-)	NCBI		Celera
Cytogenetic Map	6	p24.2	NCBI
HuRef	6	10,547,315 - 10,570,646 (-)	NCBI		HuRef
CHM1_1	6	10,673,764 - 10,697,143 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	10,539,141 - 10,562,610 (-)	NCBI		T2T-CHM13v2.0

C17h6orf52
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	23,959,124 - 23,981,978 (+)	NCBI		GRCr8
mRatBN7.2	17	23,753,359 - 23,776,251 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	23,762,746 - 23,776,245 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	23,632,792 - 23,646,285 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	25,236,261 - 25,249,755 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	23,573,761 - 23,587,254 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	21,600,326 - 21,615,888 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	21,600,432 - 21,613,930 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	23,581,681 - 23,595,498 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	29,733,271 - 29,746,771 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	23,432,376 - 23,445,886 (+)	NCBI		Celera
Cytogenetic Map	17	p12	NCBI

C5H6orf52
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	25,321,055 - 25,337,142 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	21,310,715 - 21,326,808 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	10,512,465 - 10,535,628 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	10,792,736 - 10,815,260 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	10,792,736 - 10,815,257 (-)	Ensembl	panpan1.1		panPan2

CUNH6orf52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	13,996,386 - 14,011,314 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936534	2,269,270 - 2,280,288 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

C7H6orf52
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	7,430,542 - 7,437,789 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	7,430,420 - 7,438,002 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	7,742,836 - 7,750,084 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CUNH6orf52
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	61,455,582 - 61,520,436 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	61,456,515 - 61,472,516 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	10,703,155 - 10,726,878 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CUNH6orf52
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	15,212,087 - 15,223,534 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624756	15,212,870 - 15,229,681 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in C35H6orf52
277 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium
Low	3	4	9				3		6	1	6	5
Below cutoff	2	1	13	6	6	6	3	6	6	7	4	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005640032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038446358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038584494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005317922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000048970 ⟹ ENSCAFP00000042999

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	35	10,422,255 - 10,431,048 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000068074 ⟹ ENSCAFP00000054382

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	35	10,422,262 - 10,432,336 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845034385 ⟹ ENSCAFP00845026922

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	35	10,526,554 - 10,540,504 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845034415 ⟹ ENSCAFP00845026951

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	35	10,526,554 - 10,532,590 (-)	Ensembl

RefSeq Acc Id:

XM_005640032 ⟹ XP_005640089

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	35	10,422,161 - 10,436,031 (-)	NCBI
Dog10K_Boxer_Tasha	35	10,370,981 - 10,385,015 (-)	NCBI

Sequence:

show sequence

ACGTTCTCAAGGCGAGGAGACAAAAGTTGGGAGCAAGCAGGCACGTCCTAGGTGGCCGCCAGCT
GGGCGGGTCTCAGGGGAGCAGGGCGGGGCAGCCTCTGCGGAAGCCCCTCGTTTCCGTGACGTCA
TGGGGGCGTGGCCTGCCCAGAGTGGGCGGGGCCTCTGGCGGCGTGGTGCTCTACCTCGGGAGGC
ACCTGCAGATGTGGGGTGCGGGACCCGGGACGGGAATTAGGAAGGTTAGGGAGTTCGGAAAAAG
GAAGGTCTCCTTTTTGCGCCCGAAGCACAGAGGAGGCTCCCTCCCAGTAAGGCACGGAGGGGGT
GGCCTGCGGCGTCTAGAGCAGCGCGCGAAGTCGGGGGCCCGCCCTGCGCACCTCCCTTCCAGCT
CGTCTGGCTGCGCGGACCGTGCGGTCCCTGCGGCCGGCGTCGCCCCACCACCCGGAGGAGGGGC
CAGGGCGCTAGACCCGAAGGGTGCAAGGAGGGGCCGCTCGAGCAAGCCGGGCGCACGCCGCCTC
GGCGAACGTGCCGGAGGGACTCTCACCCCCGAGCCCCGAGGTCGGCTCCGGTCGTGAAAACAGA
AATCGCCTTAATTGACGTCTGAGAGCTCCCCGTAGGGTACGGAGATGCAGAGGTCTGTTAGACA
GCACGGCTTTGCGCATGCCTGATGGAACACCTCCGGGAGCGTCAGCATCTCGCAGGGGGAAGCC
AGTGTTCCGGCCCTGCCAGGGTTACCCCTCCGGCACCTGGTTTGAGCAACAGCACTGTGGCTAC
TCCCTTTCTGTCTACGGCTGTGGCTGTGCAGCAGATGGAAGTGGAAGCCAACGCTCTGTGCGGG
AGACCTCTGGATGCCCAGCTCAATCTCTGGTCACGCCTAAGGAAAGCACAGCTCTGGCAGAGAA
ACAAGATGAAGACCCACTTGAAGATCCAAATCTTCATTTGAACATTGAGGAACTAAACAAGGAG
TTTATGGTGAAAAGTGAGGAACTCTATGACTCTCTCATGAGTTGCCACTGGCAGCCTTTGGATA
CAGTTCACTCCGAAATCCCAGATGAGGCCCCCAGAGAAACATGAGGTTCATTAGGCTACCCGAC
TGTCATATTGATTGCCTCCTGTTTTTGTTTTTGGGGAAAAAAAAAAAAAAGAAAAAGCAAATTC
TCCCAGGAAT

hide sequence

RefSeq Acc Id:

XM_038446358 ⟹ XP_038302286

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	35	10,526,377 - 10,540,527 (-)	NCBI

RefSeq Acc Id:

XM_038463102 ⟹ XP_038319030

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	35	10,371,090 - 10,385,023 (-)	NCBI

RefSeq Acc Id:

XM_038520848 ⟹ XP_038376776

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	35	10,355,805 - 10,369,564 (-)	NCBI

RefSeq Acc Id:

XM_038584494 ⟹ XP_038440422

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	35	11,723,241 - 11,737,288 (-)	NCBI

RefSeq Acc Id:

XM_038648901 ⟹ XP_038504829

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	35	10,402,708 - 10,416,783 (-)	NCBI

RefSeq Acc Id:

XR_005317922

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	35	10,371,090 - 10,381,582 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005640089	(Get FASTA)	NCBI Sequence Viewer
	XP_038302286	(Get FASTA)	NCBI Sequence Viewer
	XP_038319030	(Get FASTA)	NCBI Sequence Viewer
	XP_038376776	(Get FASTA)	NCBI Sequence Viewer
	XP_038440422	(Get FASTA)	NCBI Sequence Viewer
	XP_038504829	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000042999.2
	ENSCAFP00000054382.1
	ENSCAFP00030022510.1
	ENSCAFP00030022560.1
	ENSCAFP00040025782.1
	ENSCAFP00040025802.1
	ENSCAFP00845026922.1
	ENSCAFP00845026951.1

RefSeq Acc Id:	XP_005640089 ⟸ XM_005640032
- Peptide Label:	isoform X5
- Sequence:	show sequence MPDGTPPGASASRRGKPVFRPCQGYPSGTWFEQQHCGYSLSVYGCGCAADGSGSQRSVRETSGC PAQSLVTPKESTALAEKQDEDPLEDPNLHLNIEELNKEFMVKSEELYDSLMSCHWQPLDTVHSE IPDEAPRET hide sequence

RefSeq Acc Id:

ENSCAFP00000042999 ⟸ ENSCAFT00000048970

RefSeq Acc Id:

ENSCAFP00000054382 ⟸ ENSCAFT00000068074

RefSeq Acc Id:	XP_038376776 ⟸ XM_038520848
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038504829 ⟸ XM_038648901
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038302286 ⟸ XM_038446358
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038319030 ⟸ XM_038463102
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038440422 ⟸ XM_038584494
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSCAFP00845026951 ⟸ ENSCAFT00845034415

RefSeq Acc Id:

ENSCAFP00845026922 ⟸ ENSCAFT00845034385

Protein Domains

tRNA selenocysteine 1-associated protein 1 C-

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000030234	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030013870	UniProtKB/TrEMBL
	ENSCAFG00040016104	UniProtKB/TrEMBL
	ENSCAFG00845019493	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000048970.3	UniProtKB/TrEMBL
	ENSCAFT00000068074.2	UniProtKB/TrEMBL
	ENSCAFT00030025773.1	UniProtKB/TrEMBL
	ENSCAFT00030025829.1	UniProtKB/TrEMBL
	ENSCAFT00040029679.1	UniProtKB/TrEMBL
	ENSCAFT00040029704.1	UniProtKB/TrEMBL
	ENSCAFT00845034385.1	UniProtKB/TrEMBL
	ENSCAFT00845034415.1	UniProtKB/TrEMBL
InterPro	TSAP1	UniProtKB/TrEMBL
	TSAP1_C	UniProtKB/TrEMBL
NCBI Gene	C35H6orf52	ENTREZGENE
PANTHER	PTHR37457	UniProtKB/TrEMBL
	SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 52	UniProtKB/TrEMBL
Pfam	Trnau1ap	UniProtKB/TrEMBL
UniProt	A0A8C0N7F8_CANLF	UniProtKB/TrEMBL
	A0A8C0NCL3_CANLF	UniProtKB/TrEMBL
	A0A8I3P4Q3_CANLF	UniProtKB/TrEMBL
	A0A8I3P6P2_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:59136	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-09-12	C35H6orf52	chromosome 35 C6orf52 homolog		chromosome 35 open reading frame, human C6orf52	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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