MYOM2 (myomesin 2) - Rat Genome Database

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Gene: MYOM2 (myomesin 2) Canis lupus familiaris
Analyze
Symbol: MYOM2
Name: myomesin 2
RGD ID: 12080355
Description: ENCODES a protein that exhibits kinase binding (ortholog); INVOLVED IN extraocular skeletal muscle development (ortholog); sarcomere organization (ortholog); ASSOCIATED WITH Contracture (ortholog); FOUND IN M band (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC491446; myomesin (M-protein) 2, 165kDa; myomesin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11654,379,342 - 54,392,955 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1649,822,565 - 49,877,815 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01661,785,970 - 61,837,393 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11654,462,472 - 54,517,516 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01659,694,871 - 59,745,918 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01660,079,361 - 60,129,897 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Contracture  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
M band  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
MYOM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11654,379,342 - 54,392,955 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1649,822,565 - 49,877,815 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01661,785,970 - 61,837,393 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11654,462,472 - 54,517,516 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01659,694,871 - 59,745,918 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01660,079,361 - 60,129,897 (-)NCBIUU_Cfam_GSD_1.0
MYOM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3882,045,046 - 2,145,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl82,045,046 - 2,165,552 (+)EnsemblGRCh38hg38GRCh38
GRCh3781,993,161 - 2,093,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3681,980,565 - 2,080,787 (+)NCBINCBI36Build 36hg18NCBI36
Build 3481,980,654 - 2,080,786NCBI
Celera81,935,877 - 2,035,353 (+)NCBICelera
Cytogenetic Map8p23.3NCBI
HuRef81,809,335 - 1,908,897 (+)NCBIHuRef
CHM1_181,992,917 - 2,093,330 (+)NCBICHM1_1
T2T-CHM13v2.081,823,634 - 1,924,189 (+)NCBIT2T-CHM13v2.0
Myom2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39815,107,653 - 15,183,410 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl815,107,653 - 15,183,541 (+)EnsemblGRCm39 Ensembl
GRCm38815,057,653 - 15,133,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl815,057,653 - 15,133,541 (+)EnsemblGRCm38mm10GRCm38
MGSCv37815,057,653 - 15,133,419 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36815,057,630 - 15,133,518 (+)NCBIMGSCv36mm8
Celera815,222,231 - 15,297,079 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map87.63NCBI
Myom2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81681,222,467 - 81,295,025 (-)NCBIGRCr8
mRatBN7.21674,520,148 - 74,592,658 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1674,520,157 - 74,592,772 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1679,798,390 - 79,868,019 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01683,251,971 - 83,321,596 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01678,501,420 - 78,571,048 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01679,587,136 - 79,672,871 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1679,587,640 - 79,671,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01679,164,821 - 79,248,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41679,330,395 - 79,402,689 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11679,357,340 - 79,361,498 (-)NCBI
Celera1672,338,236 - 72,408,234 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
Myom2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540357,717,151 - 57,772,254 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540357,718,120 - 57,783,338 (-)NCBIChiLan1.0ChiLan1.0
MYOM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2716,715,741 - 16,894,105 (+)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v085,189,688 - 5,319,538 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.181,924,662 - 2,054,706 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl81,924,661 - 2,057,695 (+)Ensemblpanpan1.1panPan2
Myom2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049431,153,000 - 1,223,233 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366151,153,065 - 1,223,239 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366151,153,056 - 1,223,239 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1533,510,929 - 33,606,922 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11533,529,559 - 33,606,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21538,071,182 - 38,120,980 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYOM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.181,634,917 - 1,809,804 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl81,705,074 - 1,809,874 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605443,567,081 - 43,701,777 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myom2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248611,127,516 - 1,177,327 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248611,117,501 - 1,177,650 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MYOM2
792 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
5 4 5 23 18 12 2 6 2 6 28 22 12 14 10

Sequence


RefSeq Acc Id: XM_038452683   ⟹   XP_038308611
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1649,822,565 - 49,877,815 (+)NCBI
RefSeq Acc Id: XM_038452684   ⟹   XP_038308612
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1649,826,994 - 49,877,815 (+)NCBI
RefSeq Acc Id: XM_038498041   ⟹   XP_038353969
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11654,462,472 - 54,517,516 (+)NCBI
RefSeq Acc Id: XM_038560547   ⟹   XP_038416475
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01660,079,361 - 60,129,897 (-)NCBI
RefSeq Acc Id: XM_038560548   ⟹   XP_038416476
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01660,079,361 - 60,125,472 (-)NCBI
RefSeq Acc Id: XM_038624588   ⟹   XP_038480516
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01659,694,871 - 59,745,918 (-)NCBI
RefSeq Acc Id: XM_038624589   ⟹   XP_038480517
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01659,694,871 - 59,741,498 (-)NCBI
RefSeq Acc Id: XM_038690375   ⟹   XP_038546303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01661,785,970 - 61,837,393 (-)NCBI
RefSeq Acc Id: XM_038690376   ⟹   XP_038546304
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01661,785,970 - 61,832,966 (-)NCBI
RefSeq Acc Id: XP_038353969   ⟸   XM_038498041
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038480516   ⟸   XM_038624588
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038480517   ⟸   XM_038624589
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038546303   ⟸   XM_038690375
- Peptide Label: isoform X1
- UniProtKB: A0A8I3S511 (UniProtKB/TrEMBL),   A0A8C0QAZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038546304   ⟸   XM_038690376
- Peptide Label: isoform X2
- UniProtKB: A0A8C0QAZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308611   ⟸   XM_038452683
- Peptide Label: isoform X1
- UniProtKB: A0A8P0SQL1 (UniProtKB/TrEMBL),   A0A8C0QAZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308612   ⟸   XM_038452684
- Peptide Label: isoform X2
- UniProtKB: A0A8P0NX91 (UniProtKB/TrEMBL),   A0A8C0QAZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416475   ⟸   XM_038560547
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QAZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416476   ⟸   XM_038560548
- Peptide Label: isoform X2
- UniProtKB: A0A8C0QAZ2 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000024660 UniProtKB/TrEMBL
  ENSCAFG00040006909 UniProtKB/TrEMBL
  ENSCAFG00845024423 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000038034.4 UniProtKB/TrEMBL
  ENSCAFT00000076064.2 UniProtKB/TrEMBL
  ENSCAFT00040012846.1 UniProtKB/TrEMBL
  ENSCAFT00845043142 ENTREZGENE
  ENSCAFT00845043142.1 UniProtKB/TrEMBL
  ENSCAFT00845043604.1 UniProtKB/TrEMBL
  ENSCAFT00845043864.1 UniProtKB/TrEMBL
  ENSCAFT00845044137 ENTREZGENE
  ENSCAFT00845044137.1 UniProtKB/TrEMBL
  ENSCAFT00845044523.1 UniProtKB/TrEMBL
  ENSCAFT00845044751.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Striated_Muscle_Regulatory UniProtKB/TrEMBL
NCBI Gene LOC491446 ENTREZGENE
PANTHER PTHR13817:SF181 UniProtKB/TrEMBL
  STRETCHIN-MLCK, ISOFORM U UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
PRINTS FNTYPEIII UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt A0A8C0QAZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PNW2_CANLF UniProtKB/TrEMBL
  A0A8I3PQG6_CANLF UniProtKB/TrEMBL
  A0A8I3Q4J1_CANLF UniProtKB/TrEMBL
  A0A8I3S511 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S980_CANLF UniProtKB/TrEMBL
  A0A8I3S9B3_CANLF UniProtKB/TrEMBL
  A0A8P0NX91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SQL1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:105239 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 MYOM2  myomesin 2  MYOM2  myomesin 2  Data merged from RGD:12401161 737654 PROVISIONAL
2021-01-12 MYOM2  myomesin 2  LOC491446  myomesin-2  Symbol and/or name change 5135510 APPROVED