LOC483905 (peptidyl-prolyl cis-trans isomerase A-like) - Rat Genome Database

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Gene: LOC483905 (peptidyl-prolyl cis-trans isomerase A-like) Canis lupus familiaris
Analyze
Symbol: LOC483905
Name: peptidyl-prolyl cis-trans isomerase A-like
RGD ID: 12078937
Description: ENCODES a protein that exhibits peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN response to hypoxia (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11942,982,979 - 42,983,440 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1943,236,241 - 43,236,702 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01944,421,496 - 44,421,957 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11943,087,113 - 43,087,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01943,234,924 - 43,235,385 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01944,543,961 - 44,544,422 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:37756605  


Genomics

Comparative Map Data
LOC483905
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11942,982,979 - 42,983,440 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1943,236,241 - 43,236,702 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01944,421,496 - 44,421,957 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11943,087,113 - 43,087,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01943,234,924 - 43,235,385 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01944,543,961 - 44,544,422 (+)NCBIUU_Cfam_GSD_1.0
PPIAL4G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381148,482,548 - 148,483,302 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1148,482,548 - 148,483,302 (-)EnsemblGRCh38hg38GRCh38
GRCh371147,954,635 - 147,955,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361142,555,943 - 142,559,798 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1q21.2NCBI
CHM1_11149,850,674 - 149,851,411 (-)NCBICHM1_1
T2T-CHM13v2.01146,324,062 - 146,324,816 (+)NCBIT2T-CHM13v2.0
Ppial4g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81579,601,128 - 80,424,184 (-)NCBIGRCr8
mRatBN7.21574,015,628 - 74,016,215 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1574,015,628 - 74,016,215 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01581,576,690 - 81,577,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1581,576,888 - 81,577,379 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01585,116,093 - 85,116,680 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41580,674,328 - 80,674,915 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1573,274,951 - 73,275,646 (-)NCBICelera
Cytogenetic Map15q21NCBI

Variants

.
Variants in LOC483905
8 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system integumental system nervous system reproductive system
High
Medium
Low
Below cutoff 2 4 1 5 6

Sequence


Reference Sequences
RefSeq Acc Id: XM_038426194   ⟹   XP_038282122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01944,421,496 - 44,421,957 (+)NCBI
RefSeq Acc Id: XM_038502389   ⟹   XP_038358317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11943,087,113 - 43,087,573 (+)NCBI
RefSeq Acc Id: XM_038565107   ⟹   XP_038421035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01944,543,961 - 44,544,422 (+)NCBI
RefSeq Acc Id: XM_038629203   ⟹   XP_038485131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01943,234,924 - 43,235,385 (+)NCBI
RefSeq Acc Id: XM_541025   ⟹   XP_541025
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11942,982,979 - 42,983,440 (+)NCBI
Dog10K_Boxer_Tasha1943,236,241 - 43,236,702 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_541025   ⟸   XM_541025
- UniProtKB: A0A8C0NL57 (UniProtKB/TrEMBL),   A0A8P0SAX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038358317   ⟸   XM_038502389
RefSeq Acc Id: XP_038485131   ⟸   XM_038629203
RefSeq Acc Id: XP_038282122   ⟸   XM_038426194
- UniProtKB: A0A8I3S032 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421035   ⟸   XM_038565107
Protein Domains
PPIase cyclophilin-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005446 UniProtKB/TrEMBL
  ENSCAFG00030017928 UniProtKB/TrEMBL
  ENSCAFG00845013421 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008758.4 UniProtKB/TrEMBL
  ENSCAFT00030033048.1 UniProtKB/TrEMBL
  ENSCAFT00845023911 ENTREZGENE
  ENSCAFT00845023911.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
KEGG Report cfa:483905 UniProtKB/TrEMBL
NCBI Gene LOC483905 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A8C0NL57 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S032 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SAX9 ENTREZGENE
UniProt Secondary A0A8P0SAX9 UniProtKB/TrEMBL