PLA2G3 (phospholipase A2 group III) - Rat Genome Database

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Gene: PLA2G3 (phospholipase A2 group III) Canis lupus familiaris
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Symbol: PLA2G3
Name: phospholipase A2 group III
RGD ID: 12075173
Description: ENCODES a protein that exhibits calcium-dependent phospholipase A2 activity (inferred); phospholipase A2 activity (inferred); phospholipase activity (inferred); INVOLVED IN acrosome assembly (ortholog); cell development (ortholog); cell maturation (ortholog); FOUND IN centriole (inferred); extracellular region (inferred); recycling endosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: group 3 secretory phospholipase A2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,127,074 - 24,132,508 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,128,005 - 24,132,508 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,994,204 - 24,002,589 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,506,855 - 24,515,226 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,510,739 - 24,515,226 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,210,260 - 24,218,645 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,472,253 - 24,480,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,533,532 - 24,541,902 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PLA2G3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,127,074 - 24,132,508 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,128,005 - 24,132,508 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,994,204 - 24,002,589 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,506,855 - 24,515,226 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,510,739 - 24,515,226 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,210,260 - 24,218,645 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,472,253 - 24,480,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,533,532 - 24,541,902 (-)NCBIUU_Cfam_GSD_1.0
PLA2G3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,134,807 - 31,140,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,134,807 - 31,140,508 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,530,793 - 31,536,494 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,860,793 - 29,866,469 (-)NCBINCBI36Build 36hg18NCBI36
Build 342229,855,346 - 29,861,023NCBI
Celera2215,330,868 - 15,336,544 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,492,451 - 14,498,127 (-)NCBIHuRef
CHM1_12231,490,658 - 31,496,334 (-)NCBICHM1_1
T2T-CHM13v2.02231,598,311 - 31,604,012 (-)NCBIT2T-CHM13v2.0
Pla2g3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,438,158 - 3,449,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,438,284 - 3,449,350 (+)EnsemblGRCm39 Ensembl
GRCm38113,488,158 - 3,499,346 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,488,284 - 3,499,350 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,388,230 - 3,394,169 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,388,302 - 3,399,353 (+)NCBIMGSCv36mm8
Celera113,979,003 - 3,985,078 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.45NCBI
Pla2g3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,589,908 - 82,597,542 (+)NCBIGRCr8
mRatBN7.21478,367,625 - 78,373,913 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,368,105 - 78,373,913 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,809,429 - 82,815,114 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,049,536 - 84,055,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,495,298 - 80,500,983 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,724,828 - 83,730,614 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,724,933 - 83,730,614 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,412,999 - 84,418,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,119,872 - 84,125,552 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,130,645 - 84,143,800 (+)NCBI
Celera1477,281,569 - 77,287,249 (+)NCBICelera
Cytogenetic Map14q21NCBI
Pla2g3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,315,450 - 5,320,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,314,520 - 5,320,151 (-)NCBIChiLan1.0ChiLan1.0
PLA2G3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,090,380 - 41,100,730 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,788,928 - 43,799,272 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,158,589 - 12,164,441 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,995,364 - 30,001,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,995,364 - 30,001,160 (-)Ensemblpanpan1.1panPan2
Pla2g3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,049,648 - 117,058,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755306,313 - 312,683 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755307,166 - 312,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,923,954 - 47,928,810 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,923,005 - 47,928,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,034,721 - 51,040,254 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11914,025,373 - 14,033,214 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1914,025,742 - 14,030,643 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,087,770 - 112,093,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla2g3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,603,277 - 7,607,753 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,602,848 - 7,607,872 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLA2G3
47 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
2 5 4 21 14 10 1 6 15 10 12 11 10

Sequence


Ensembl Acc Id: ENSCAFT00000020599   ⟹   ENSCAFP00000019117
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2624,128,005 - 24,132,508 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000035185   ⟹   ENSCAFP00000030417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2624,128,005 - 24,132,508 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845039214   ⟹   ENSCAFP00845030714
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2624,510,739 - 24,515,226 (-)Ensembl
RefSeq Acc Id: XM_038437280   ⟹   XP_038293208
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02624,506,855 - 24,515,226 (-)NCBI
RefSeq Acc Id: XM_038512177   ⟹   XP_038368105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12624,210,260 - 24,218,645 (-)NCBI
RefSeq Acc Id: XM_038575678   ⟹   XP_038431606
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02624,533,532 - 24,541,902 (-)NCBI
RefSeq Acc Id: XM_038639873   ⟹   XP_038495801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02624,472,253 - 24,480,619 (-)NCBI
RefSeq Acc Id: XM_543487   ⟹   XP_543487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12624,127,074 - 24,132,508 (-)NCBI
Dog10K_Boxer_Tasha2623,994,204 - 24,002,589 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543487   ⟸   XM_543487
- UniProtKB: A0A8C0JM46 (UniProtKB/TrEMBL),   A0A8C0TLK4 (UniProtKB/TrEMBL),   A0A8I3PFI3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000030417   ⟸   ENSCAFT00000035185
Ensembl Acc Id: ENSCAFP00000019117   ⟸   ENSCAFT00000020599
RefSeq Acc Id: XP_038368105   ⟸   XM_038512177
RefSeq Acc Id: XP_038495801   ⟸   XM_038639873
RefSeq Acc Id: XP_038293208   ⟸   XM_038437280
- UniProtKB: A0A8C0JM46 (UniProtKB/TrEMBL),   A0A8C0TLK4 (UniProtKB/TrEMBL),   A0A8I3PFI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431606   ⟸   XM_038575678
- UniProtKB: A0A8C0JM46 (UniProtKB/TrEMBL),   A0A8C0TLK4 (UniProtKB/TrEMBL),   A0A8I3PFI3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845030714   ⟸   ENSCAFT00845039214
Protein Domains
Phospholipase A2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012981 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018638 UniProtKB/TrEMBL
  ENSCAFG00040023639 UniProtKB/TrEMBL
  ENSCAFG00845022232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020599.5 UniProtKB/TrEMBL
  ENSCAFT00030034356.1 UniProtKB/TrEMBL
  ENSCAFT00040044018.1 UniProtKB/TrEMBL
  ENSCAFT00845039214 ENTREZGENE
  ENSCAFT00845039214.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.90.10 UniProtKB/TrEMBL
InterPro PLipase_A2_dom UniProtKB/TrEMBL
  PLipase_A2_dom_sf UniProtKB/TrEMBL
  PLipase_A2_His_AS UniProtKB/TrEMBL
KEGG Report cfa:486361 UniProtKB/TrEMBL
NCBI Gene PLA2G3 ENTREZGENE
PANTHER GROUP 3 SECRETORY PHOSPHOLIPASE A2 UniProtKB/TrEMBL
  RH14732P UniProtKB/TrEMBL
Pfam Phospholip_A2_2 UniProtKB/TrEMBL
PROSITE PA2_HIS UniProtKB/TrEMBL
Superfamily-SCOP SSF48619 UniProtKB/TrEMBL
UniProt A0A8C0JM46 ENTREZGENE
  A0A8C0TLK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PFI3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44625 ENTREZGENE