NIT1 (nitrilase 1) - Rat Genome Database

Name: NIT1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NIT1 (nitrilase 1) Canis lupus familiaris

Analyze

Symbol:

NIT1

Name:

nitrilase 1

RGD ID:

12075072

Description:

ENCODES a protein that exhibits deaminated glutathione amidase activity (ortholog); INVOLVED IN amide catabolic process (ortholog); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

deaminated glutathione amidase; nitrilase homolog 1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NIT1 (nitrilase 1)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	21,352,236 - 21,355,636 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	21,348,486 - 21,356,260 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,701 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	21,469,764 - 21,473,194 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	21,466,017 - 21,473,864 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	21,357,920 - 21,361,348 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,377 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,607 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune interstitial lung, joint, and kidney disease (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amide catabolic process (ISO)

nucleobase-containing compound metabolic process (IEA)

Cellular Component

cytoplasm (ISO)

mitochondrion (ISO)

Molecular Function

bis(5'-adenosyl)-triphosphatase activity (IEA)

deaminated glutathione amidase activity (ISO)

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

NIT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	21,352,236 - 21,355,636 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	21,348,486 - 21,356,260 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,701 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	21,469,764 - 21,473,194 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	21,466,017 - 21,473,864 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	21,357,920 - 21,361,348 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,377 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,607 (-)	NCBI		UU_Cfam_GSD_1.0

NIT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	161,118,105 - 161,125,445 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	161,118,086 - 161,125,445 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	161,087,895 - 161,095,235 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	159,354,515 - 159,357,481 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	157,900,963 - 157,903,930	NCBI
Celera	1	134,155,024 - 134,162,397 (+)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	132,445,260 - 132,452,414 (+)	NCBI		HuRef
CHM1_1	1	162,484,103 - 162,491,482 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	160,255,512 - 160,262,920 (+)	NCBI		T2T-CHM13v2.0

Nit1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	171,168,145 - 171,173,209 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	171,165,576 - 171,173,214 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	171,340,571 - 171,345,656 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	171,338,008 - 171,345,646 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	173,272,368 - 173,275,776 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	173,178,919 - 173,182,301 (-)	NCBI		MGSCv36	mm8
Celera	1	173,793,725 - 173,797,135 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	79.35	NCBI

Nit1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI		GRCr8
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,765,941 - 83,773,332 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	86,275,650 - 86,279,086 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,673,861 - 87,677,297 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,909,943 - 84,913,387 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,722,374 - 89,725,806 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	94,349,703 - 94,353,139 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	87,242,619 - 87,246,055 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	87,431,510 - 87,434,235 (-)	NCBI
Celera	13	83,400,571 - 83,404,007 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

Nit1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	12,882,765 - 12,888,479 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	12,882,765 - 12,885,642 (+)	NCBI	ChiLan1.0	ChiLan1.0

NIT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	88,730,947 - 88,733,951 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	88,421,282 - 88,424,287 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	136,530,490 - 136,533,619 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	140,443,751 - 140,446,874 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	140,443,763 - 140,449,831 (+)	Ensembl	panpan1.1		panPan2

Nit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	7,223,645 - 7,228,035 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936903	431,897 - 439,718 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936903	432,585 - 436,697 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NIT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	89,320,712 - 89,327,066 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	89,323,598 - 89,327,057 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	97,180,537 - 97,183,754 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NIT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	2,859,582 - 2,862,688 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	2,860,008 - 2,862,601 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	1,906,929 - 1,910,035 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nit1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	254,766 - 257,759 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	254,766 - 258,046 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NIT1
33 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	2	22	6	6	6	6		12	8	10	6
Low		3						6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014111227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022415431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022415432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022415433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022415434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_536134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000020199 ⟹ ENSCAFP00000018737

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	21,352,254 - 21,356,260 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000067716 ⟹ ENSCAFP00000044266

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	21,352,254 - 21,356,260 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000069279 ⟹ ENSCAFP00000055865

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	21,348,486 - 21,356,260 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845052769 ⟹ ENSCAFP00845041428

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	21,466,017 - 21,473,135 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845052787 ⟹ ENSCAFP00845041443

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	21,469,764 - 21,473,864 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845052800 ⟹ ENSCAFP00845041450

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	21,469,764 - 21,473,864 (-)	Ensembl

RefSeq Acc Id:

XM_022415432 ⟹ XP_022271140

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	21,352,236 - 21,355,481 (-)	NCBI
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,518 (-)	NCBI

Sequence:

show sequence

GCTGCGCCTGGGAGAGGCGGAGAGGCCGGGTTGACCGGAGCGTGGGGGCGCGGGCTGGGATGTG
TGTGGGTGCCGGTGCCCTTTGCCCCCCACGGGGTGGGAGGGGCGAGGGACGGTGAGCTTCCCCT
CGGAGATGGGGGCTGGGCTTCATCATCAGGCCTCCTCACCAGCTCCTGCCCCTTCTCTTGTGTC
CTGGACTCCGGATACCTCGACTCTCAGTACTTTGTGCACAGCCCAGTCCCAGAGCCATGGCTAT
CTCCTCTTCTTCCTGGGAACTGCCGCTGGTGGCTGTGTGCCAGGTAACATCAACACCAGACAAG
CAGGAGAACTTTAAAACATGCGCCGAGCTTGTTCGAGAGGCTGCCAGACTGGGTGCTTGCCTGG
CTTTCCTGCCTGAGGCATTTGACTTCATTGCAAGGGACCCTGCAGAGACACTACGCCTGTCTGA
GCCACTGGGTGGGAACCTTTTGGGAGAATATACCCAGCTTGCCAGGGAATGTGGACTCTGGCTG
TCCTTGGGTGGTTTCCATGAGCGAGGCCAAGACTGGGAGCAGACTCAGAAAATCTACAATTGCC
ATGTGCTTCTAAACAACGAGGGGTCAGTAGTGGCCACTTACAGGAAGACCCATCTGTGTGACGT
GGAGATTCCTGGGCAGGGGCCTATGCGTGAGAGCAACTCTACCATTCCTGGGCCCAGTCTTGAG
TCTCCTGTCAGCACACCAGCAGGCAAGATTGGTCTAGCTATCTGCTATGATATGCGGTTTCCTG
AACTCTCTCTGGCATTGGCTCAGGCTGGAGCAGAAATACTCACCTACCCTTCAGCTTTTGGATC
TGTTACAGGCCCAGCCCACTGGGAGGTGTTGCTGCGGGCCCGTGCCATTGAAACCCAGTGCTAC
GTAGTGGCGGCAGCACAGTGTGGACGCCACCACGAGAAGAGAGCAAGTTATGGCCACAGCATGG
TGGTGGATCCCTGGGGAACAGTGGTGGCCCGCTGCTCTGAAGGACCAGGCCTCTGCCTTGCCCG
AATTGACCTCAATTATCTGCGGCAGTTACGCCAACACCTGCCTGTGTTCCAGCACCGCAGGCCT
GACCTCTATGGCAATCTGGGCCACCCATTGTCTTAAGACTTTGACTTCTGGAAGTTGAGACTCC
CACTGTGAGCTGGTGTGGCTGTGACTTGAAGGCAGGACCCAGGCGCGGCTCCCCTCACTGGGAG
AACCTTGACTCTCTCGAATGAACACAGGCTCAGCTTCTTGGGAAAGAAGAAGCTTTCACCTGAG
CTCAGATTTCAGTTTCAGAAAGGTGGAATTTTATATAGTCACTGTTTATTTCATGAAAACTGAC
GTTATGCTGAGGGCTGAGCAGCACTGGCATTGAAAAAAATATAACCATCATAAAGTC

hide sequence

RefSeq Acc Id:

XM_022415433 ⟹ XP_022271141

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	21,352,236 - 21,355,328 (-)	NCBI
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,362 (-)	NCBI

Sequence:

show sequence

GCTGAGCAGTGCCGCCGTGCAGGCTGGGCTTCATCATCAGGCCTCCTCACCAGCTCCTGCCCCT
TCTCTTGTGTCCTGGACTCCGGATACCTCGACTCTCAGTACTTTGTGCACAGCCCAGTCCCAGA
GCCATGGCTATCTCCTCTTCTTCCTGGGAACTGCCGCTGGTGGCTGTGTGCCAGGTAACATCAA
CACCAGACAAGCAGGAGAACTTTAAAACATGCGCCGAGCTTGTTCGAGAGGCTGCCAGACTGGG
TGCTTGCCTGGCTTTCCTGCCTGAGGCATTTGACTTCATTGCAAGGGACCCTGCAGAGACACTA
CGCCTGTCTGAGCCACTGGGTGGGAACCTTTTGGGAGAATATACCCAGCTTGCCAGGGAATGTG
GACTCTGGCTGTCCTTGGGTGGTTTCCATGAGCGAGGCCAAGACTGGGAGCAGACTCAGAAAAT
CTACAATTGCCATGTGCTTCTAAACAACGAGGGGTCAGTAGTGGCCACTTACAGGAAGACCCAT
CTGTGTGACGTGGAGATTCCTGGGCAGGGGCCTATGCGTGAGAGCAACTCTACCATTCCTGGGC
CCAGTCTTGAGTCTCCTGTCAGCACACCAGCAGGCAAGATTGGTCTAGCTATCTGCTATGATAT
GCGGTTTCCTGAACTCTCTCTGGCATTGGCTCAGGCTGGAGCAGAAATACTCACCTACCCTTCA
GCTTTTGGATCTGTTACAGGCCCAGCCCACTGGGAGGTGTTGCTGCGGGCCCGTGCCATTGAAA
CCCAGTGCTACGTAGTGGCGGCAGCACAGTGTGGACGCCACCACGAGAAGAGAGCAAGTTATGG
CCACAGCATGGTGGTGGATCCCTGGGGAACAGTGGTGGCCCGCTGCTCTGAAGGACCAGGCCTC
TGCCTTGCCCGAATTGACCTCAATTATCTGCGGCAGTTACGCCAACACCTGCCTGTGTTCCAGC
ACCGCAGGCCTGACCTCTATGGCAATCTGGGCCACCCATTGTCTTAAGACTTTGACTTCTGGAA
GTTGAGACTCCCACTGTGAGCTGGTGTGGCTGTGACTTGAAGGCAGGACCCAGGCGCGGCTCCC
CTCACTGGGAGAACCTTGACTCTCTCGAATGAACACAGGCTCAGCTTCTTGGGAAAGAAGAAGC
TTTCACCTGAGCTCAGATTTCAGTTTCAGAAAGGTGGAATTTTATATAGTCACTGTTTATTTCA
TGAAAACTGACGTTATGCTGAGGGCTGAGCAGCACTGGCATTGAAAAAAATATAACCATCATAA
AGTC

hide sequence

RefSeq Acc Id:

XM_038448633 ⟹ XP_038304561

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	21,469,764 - 21,472,915 (-)	NCBI

RefSeq Acc Id:

XM_038448634 ⟹ XP_038304562

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	21,469,764 - 21,473,194 (-)	NCBI

RefSeq Acc Id:

XM_038448635 ⟹ XP_038304563

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	21,469,764 - 21,472,971 (-)	NCBI

RefSeq Acc Id:

XM_038448636 ⟹ XP_038304564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	21,469,764 - 21,473,011 (-)	NCBI

RefSeq Acc Id:

XM_038448637 ⟹ XP_038304565

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	21,469,764 - 21,472,855 (-)	NCBI

RefSeq Acc Id:

XM_038463910 ⟹ XP_038319838

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,422 (-)	NCBI

RefSeq Acc Id:

XM_038463911 ⟹ XP_038319839

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,478 (-)	NCBI

RefSeq Acc Id:

XM_038522519 ⟹ XP_038378447

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	21,357,920 - 21,361,069 (-)	NCBI

RefSeq Acc Id:

XM_038522520 ⟹ XP_038378448

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	21,357,920 - 21,361,348 (-)	NCBI

RefSeq Acc Id:

XM_038522521 ⟹ XP_038378449

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	21,357,920 - 21,361,125 (-)	NCBI

RefSeq Acc Id:

XM_038522522 ⟹ XP_038378450

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	21,357,920 - 21,361,165 (-)	NCBI

RefSeq Acc Id:

XM_038522523 ⟹ XP_038378451

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	21,357,920 - 21,361,009 (-)	NCBI

RefSeq Acc Id:

XM_038586299 ⟹ XP_038442227

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,328 (-)	NCBI

RefSeq Acc Id:

XM_038586300 ⟹ XP_038442228

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,607 (-)	NCBI

RefSeq Acc Id:

XM_038586301 ⟹ XP_038442229

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,384 (-)	NCBI

RefSeq Acc Id:

XM_038586302 ⟹ XP_038442230

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,424 (-)	NCBI

RefSeq Acc Id:

XM_038586303 ⟹ XP_038442231

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,268 (-)	NCBI

RefSeq Acc Id:

XM_038650719 ⟹ XP_038506647

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,098 (-)	NCBI

RefSeq Acc Id:

XM_038650720 ⟹ XP_038506648

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,377 (-)	NCBI

RefSeq Acc Id:

XM_038650721 ⟹ XP_038506649

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,154 (-)	NCBI

RefSeq Acc Id:

XM_038650722 ⟹ XP_038506650

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,194 (-)	NCBI

RefSeq Acc Id:

XM_038650723 ⟹ XP_038506651

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,038 (-)	NCBI

RefSeq Acc Id:

XM_536134 ⟹ XP_536134

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	21,352,236 - 21,355,636 (-)	NCBI
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,701 (-)	NCBI

Sequence:

show sequence

GTCACATCCGGCCTGGAGGTTGCCGCCCCCTGGCCCCGGGGCCGCCGCTTCCAGGCCGCTCCTC
CGGTCGGACGCTGCCGACGGTTTCGGCTCTATCCTCATGCTGGGCTTCATCATCAGGCCTCCTC
ACCAGCTCCTGCCCCTTCTCTTGTGTCCTGGACTCCGGATACCTCGACTCTCAGTACTTTGTGC
ACAGCCCAGTCCCAGAGCCATGGCTATCTCCTCTTCTTCCTGGGAACTGCCGCTGGTGGCTGTG
TGCCAGGTAACATCAACACCAGACAAGCAGGAGAACTTTAAAACATGCGCCGAGCTTGTTCGAG
AGGCTGCCAGACTGGGTGCTTGCCTGGCTTTCCTGCCTGAGGCATTTGACTTCATTGCAAGGGA
CCCTGCAGAGACACTACGCCTGTCTGAGCCACTGGGTGGGAACCTTTTGGGAGAATATACCCAG
CTTGCCAGGGAATGTGGACTCTGGCTGTCCTTGGGTGGTTTCCATGAGCGAGGCCAAGACTGGG
AGCAGACTCAGAAAATCTACAATTGCCATGTGCTTCTAAACAACGAGGGGTCAGTAGTGGCCAC
TTACAGGAAGACCCATCTGTGTGACGTGGAGATTCCTGGGCAGGGGCCTATGCGTGAGAGCAAC
TCTACCATTCCTGGGCCCAGTCTTGAGTCTCCTGTCAGCACACCAGCAGGCAAGATTGGTCTAG
CTATCTGCTATGATATGCGGTTTCCTGAACTCTCTCTGGCATTGGCTCAGGCTGGAGCAGAAAT
ACTCACCTACCCTTCAGCTTTTGGATCTGTTACAGGCCCAGCCCACTGGGAGGTGTTGCTGCGG
GCCCGTGCCATTGAAACCCAGTGCTACGTAGTGGCGGCAGCACAGTGTGGACGCCACCACGAGA
AGAGAGCAAGTTATGGCCACAGCATGGTGGTGGATCCCTGGGGAACAGTGGTGGCCCGCTGCTC
TGAAGGACCAGGCCTCTGCCTTGCCCGAATTGACCTCAATTATCTGCGGCAGTTACGCCAACAC
CTGCCTGTGTTCCAGCACCGCAGGCCTGACCTCTATGGCAATCTGGGCCACCCATTGTCTTAAG
ACTTTGACTTCTGGAAGTTGAGACTCCCACTGTGAGCTGGTGTGGCTGTGACTTGAAGGCAGGA
CCCAGGCGCGGCTCCCCTCACTGGGAGAACCTTGACTCTCTCGAATGAACACAGGCTCAGCTTC
TTGGGAAAGAAGAAGCTTTCACCTGAGCTCAGATTTCAGTTTCAGAAAGGTGGAATTTTATATA
GTCACTGTTTATTTCATGAAAACTGACGTTATGCTGAGGGCTGAGCAGCACTGGCATTGAAAAA
AATATAACCATCATAAAGTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_022271140	(Get FASTA)	NCBI Sequence Viewer
	XP_022271141	(Get FASTA)	NCBI Sequence Viewer
	XP_038304561	(Get FASTA)	NCBI Sequence Viewer
	XP_038304562	(Get FASTA)	NCBI Sequence Viewer
	XP_038304563	(Get FASTA)	NCBI Sequence Viewer
	XP_038304564	(Get FASTA)	NCBI Sequence Viewer
	XP_038304565	(Get FASTA)	NCBI Sequence Viewer
	XP_038319838	(Get FASTA)	NCBI Sequence Viewer
	XP_038319839	(Get FASTA)	NCBI Sequence Viewer
	XP_038378447	(Get FASTA)	NCBI Sequence Viewer
	XP_038378448	(Get FASTA)	NCBI Sequence Viewer
	XP_038378449	(Get FASTA)	NCBI Sequence Viewer
	XP_038378450	(Get FASTA)	NCBI Sequence Viewer
	XP_038378451	(Get FASTA)	NCBI Sequence Viewer
	XP_038442227	(Get FASTA)	NCBI Sequence Viewer
	XP_038442228	(Get FASTA)	NCBI Sequence Viewer
	XP_038442229	(Get FASTA)	NCBI Sequence Viewer
	XP_038442230	(Get FASTA)	NCBI Sequence Viewer
	XP_038442231	(Get FASTA)	NCBI Sequence Viewer
	XP_038506647	(Get FASTA)	NCBI Sequence Viewer
	XP_038506648	(Get FASTA)	NCBI Sequence Viewer
	XP_038506649	(Get FASTA)	NCBI Sequence Viewer
	XP_038506650	(Get FASTA)	NCBI Sequence Viewer
	XP_038506651	(Get FASTA)	NCBI Sequence Viewer
	XP_536134	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000018737.4
	ENSCAFP00000044266.2
	ENSCAFP00000055865.1
	ENSCAFP00030030305.1
	ENSCAFP00030030326.1
	ENSCAFP00030030347.1
	ENSCAFP00040022600.1
	ENSCAFP00845041428.1
	ENSCAFP00845041443.1
	ENSCAFP00845041450.1

RefSeq Acc Id:

XP_536134 ⟸ XM_536134

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLGFIIRPPHQLLPLLLCPGLRIPRLSVLCAQPSPRAMAISSSSWELPLVAVCQVTSTPDKQEN
FKTCAELVREAARLGACLAFLPEAFDFIARDPAETLRLSEPLGGNLLGEYTQLARECGLWLSLG
GFHERGQDWEQTQKIYNCHVLLNNEGSVVATYRKTHLCDVEIPGQGPMRESNSTIPGPSLESPV
STPAGKIGLAICYDMRFPELSLALAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIETQCYVVA
AAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNYLRQLRQHLPVFQHRRPDLY
GNLGHPLS

hide sequence

RefSeq Acc Id:

XP_022271140 ⟸ XM_022415432

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAISSSSWELPLVAVCQVTSTPDKQENFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLR
LSEPLGGNLLGEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNNEGSVVATYRKTHL
CDVEIPGQGPMRESNSTIPGPSLESPVSTPAGKIGLAICYDMRFPELSLALAQAGAEILTYPSA
FGSVTGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLC
LARIDLNYLRQLRQHLPVFQHRRPDLYGNLGHPLS

hide sequence

RefSeq Acc Id:

XP_022271141 ⟸ XM_022415433

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAISSSSWELPLVAVCQVTSTPDKQENFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLR
LSEPLGGNLLGEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNNEGSVVATYRKTHL
CDVEIPGQGPMRESNSTIPGPSLESPVSTPAGKIGLAICYDMRFPELSLALAQAGAEILTYPSA
FGSVTGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLC
LARIDLNYLRQLRQHLPVFQHRRPDLYGNLGHPLS

hide sequence

RefSeq Acc Id:

ENSCAFP00000055865 ⟸ ENSCAFT00000069279

RefSeq Acc Id:

ENSCAFP00000044266 ⟸ ENSCAFT00000067716

RefSeq Acc Id:

ENSCAFP00000018737 ⟸ ENSCAFT00000020199

RefSeq Acc Id:	XP_038378448 ⟸ XM_038522520
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038378450 ⟸ XM_038522522
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038378449 ⟸ XM_038522521
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038378447 ⟸ XM_038522519
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038378451 ⟸ XM_038522523
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038506648 ⟸ XM_038650720
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038506650 ⟸ XM_038650722
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038506649 ⟸ XM_038650721
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038506647 ⟸ XM_038650719
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038506651 ⟸ XM_038650723
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038304562 ⟸ XM_038448634
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038304564 ⟸ XM_038448636
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038304563 ⟸ XM_038448635
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038304561 ⟸ XM_038448633
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038304565 ⟸ XM_038448637
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038319839 ⟸ XM_038463911
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038319838 ⟸ XM_038463910
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038442228 ⟸ XM_038586300
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038442230 ⟸ XM_038586302
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038442229 ⟸ XM_038586301
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038442227 ⟸ XM_038586299
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038442231 ⟸ XM_038586303
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSCAFP00845041450 ⟸ ENSCAFT00845052800

RefSeq Acc Id:

ENSCAFP00845041428 ⟸ ENSCAFT00845052769

RefSeq Acc Id:

ENSCAFP00845041443 ⟸ ENSCAFT00845052787

Protein Domains

CN hydrolase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000012736	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030018902	UniProtKB/TrEMBL
	ENSCAFG00040014076	UniProtKB/TrEMBL
	ENSCAFG00845029792	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020199.5	UniProtKB/TrEMBL
	ENSCAFT00000067716.2	UniProtKB/TrEMBL
	ENSCAFT00000069279.2	UniProtKB/TrEMBL
	ENSCAFT00030034754.1	UniProtKB/TrEMBL
	ENSCAFT00030034782.1	UniProtKB/TrEMBL
	ENSCAFT00030034807.1	UniProtKB/TrEMBL
	ENSCAFT00040025986.1	UniProtKB/TrEMBL
	ENSCAFT00845052769.1	UniProtKB/TrEMBL
	ENSCAFT00845052787.1	UniProtKB/TrEMBL
	ENSCAFT00845052800.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.110.10	UniProtKB/TrEMBL
InterPro	C-N_Hydrolase	UniProtKB/TrEMBL
	C-N_Hydrolase_sf	UniProtKB/TrEMBL
	Nit1/2_C-N_Hydrolase	UniProtKB/TrEMBL
	UPF0012_CS	UniProtKB/TrEMBL
NCBI Gene	NIT1	ENTREZGENE
PANTHER	DEAMINATED GLUTATHIONE AMIDASE	UniProtKB/TrEMBL
	NITRILASE-RELATED	UniProtKB/TrEMBL
Pfam	CN_hydrolase	UniProtKB/TrEMBL
PROSITE	CN_HYDROLASE	UniProtKB/TrEMBL
	UPF0012	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56317	UniProtKB/TrEMBL
UniProt	A0A8C0NXQ9_CANLF	UniProtKB/TrEMBL
	A0A8C0P676_CANLF	UniProtKB/TrEMBL
	A0A8C0RNF4_CANLF	UniProtKB/TrEMBL
	A0A8I3Q2G4_CANLF	UniProtKB/TrEMBL
	A0A8I3Q4L6_CANLF	UniProtKB/TrEMBL
	A0A8I3SCG0_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:53123	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar