CNFN (cornifelin) - Rat Genome Database

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Gene: CNFN (cornifelin) Canis lupus familiaris
Analyze
Symbol: CNFN
Name: cornifelin
RGD ID: 12074657
Description: ASSOCIATED WITH Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); craniosynostosis (ortholog); FOUND IN cornified envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,014,089 - 112,015,884 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,014,746 - 112,015,784 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,440,313 - 111,442,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,626,623 - 112,628,816 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,626,550 - 112,628,827 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,181,016 - 112,183,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,816,598 - 111,818,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,743,466 - 112,745,667 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CNFN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,014,089 - 112,015,884 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,014,746 - 112,015,784 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,440,313 - 111,442,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,626,623 - 112,628,816 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,626,550 - 112,628,827 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,181,016 - 112,183,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,816,598 - 111,818,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,743,466 - 112,745,667 (+)NCBIUU_Cfam_GSD_1.0
CNFN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,387,019 - 42,390,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,387,019 - 42,390,297 (-)EnsemblGRCh38hg38GRCh38
GRCh371942,891,171 - 42,894,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,583,011 - 47,586,279 (-)NCBINCBI36Build 36hg18NCBI36
Build 341947,583,012 - 47,586,279NCBI
Celera1939,691,960 - 39,695,233 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,321,303 - 39,324,576 (-)NCBIHuRef
CHM1_11942,892,821 - 42,896,094 (-)NCBICHM1_1
T2T-CHM13v2.01945,206,404 - 45,209,682 (-)NCBIT2T-CHM13v2.0
Cnfn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,067,041 - 25,069,149 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,067,045 - 25,069,149 (-)EnsemblGRCm39 Ensembl
GRCm38725,367,616 - 25,369,724 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,367,620 - 25,369,724 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,152,635 - 26,154,743 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,076,376 - 25,078,484 (-)NCBIMGSCv36mm8
Celera719,982,942 - 19,985,050 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.78NCBI
Cnfn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,079,409 - 90,081,556 (-)NCBIGRCr8
mRatBN7.2180,949,699 - 80,953,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,951,600 - 80,953,747 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,343,805 - 86,345,952 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,894,988 - 94,897,129 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,099,586 - 88,101,733 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,234,032 - 82,236,602 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,234,032 - 82,236,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,497,889 - 83,500,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,641,315 - 80,643,462 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera175,394,653 - 75,396,800 (-)NCBICelera
Cytogenetic Map1q21NCBI
Cnfn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555541,708 - 543,878 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555541,648 - 543,878 (+)NCBIChiLan1.0ChiLan1.0
CNFN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,492,017 - 48,494,034 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,360,626 - 50,362,645 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,274,761 - 39,278,019 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,865,155 - 47,870,187 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,865,155 - 47,870,162 (-)Ensemblpanpan1.1panPan2
Cnfn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,801,619 - 15,803,745 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706149,643 - 151,088 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706149,643 - 151,088 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNFN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,570,032 - 49,572,284 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,568,224 - 49,574,070 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,464,162 - 45,466,783 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNFN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,588,366 - 36,591,983 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,588,503 - 36,590,211 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,834,550 - 14,836,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnfn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907390,156 - 391,549 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907389,351 - 391,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CNFN
43 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 1
Medium 5
Low 1 1 1 3 1
Below cutoff 3 7 1 1 2 6 8 3 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003432576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038465065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038465066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038465067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038589867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038589868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038589870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038653789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038653790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038653791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000007759   ⟹   ENSCAFP00000007191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1112,014,746 - 112,015,784 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845001235   ⟹   ENSCAFP00845000941
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1112,626,550 - 112,628,827 (+)Ensembl
RefSeq Acc Id: XM_038443232   ⟹   XP_038299160
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1111,440,381 - 111,442,508 (+)NCBI
RefSeq Acc Id: XM_038443273   ⟹   XP_038299201
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1111,440,389 - 111,442,508 (+)NCBI
RefSeq Acc Id: XM_038443339   ⟹   XP_038299267
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1111,440,313 - 111,442,508 (+)NCBI
RefSeq Acc Id: XM_038465065   ⟹   XP_038320993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,181,084 - 112,183,206 (+)NCBI
RefSeq Acc Id: XM_038465066   ⟹   XP_038320994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,181,092 - 112,183,206 (+)NCBI
RefSeq Acc Id: XM_038465067   ⟹   XP_038320995
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,181,016 - 112,183,206 (+)NCBI
RefSeq Acc Id: XM_038525660   ⟹   XP_038381588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,743,534 - 112,745,667 (+)NCBI
RefSeq Acc Id: XM_038525661   ⟹   XP_038381589
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,743,542 - 112,745,667 (+)NCBI
RefSeq Acc Id: XM_038525662   ⟹   XP_038381590
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,743,466 - 112,745,667 (+)NCBI
RefSeq Acc Id: XM_038589867   ⟹   XP_038445795
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,816,666 - 111,818,792 (+)NCBI
RefSeq Acc Id: XM_038589868   ⟹   XP_038445796
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,816,674 - 111,818,792 (+)NCBI
RefSeq Acc Id: XM_038589870   ⟹   XP_038445798
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,816,598 - 111,818,792 (+)NCBI
RefSeq Acc Id: XM_038653789   ⟹   XP_038509717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,626,691 - 112,628,816 (+)NCBI
RefSeq Acc Id: XM_038653790   ⟹   XP_038509718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,626,699 - 112,628,816 (+)NCBI
RefSeq Acc Id: XM_038653791   ⟹   XP_038509719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,626,623 - 112,628,816 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000007191   ⟸   ENSCAFT00000007759
RefSeq Acc Id: XP_038320995   ⟸   XM_038465067
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038320993   ⟸   XM_038465065
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038320994   ⟸   XM_038465066
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038445798   ⟸   XM_038589870
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038445795   ⟸   XM_038589867
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038445796   ⟸   XM_038589868
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038509719   ⟸   XM_038653791
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038509717   ⟸   XM_038653789
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038509718   ⟸   XM_038653790
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299267   ⟸   XM_038443339
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299160   ⟸   XM_038443232
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299201   ⟸   XM_038443273
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381590   ⟸   XM_038525662
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381588   ⟸   XM_038525660
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381589   ⟸   XM_038525661
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJE5 (UniProtKB/TrEMBL),   A0A8I3MBH4 (UniProtKB/TrEMBL),   A0A8P0SAD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845000941   ⟸   ENSCAFT00845001235


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004814 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004476 UniProtKB/TrEMBL
  ENSCAFG00040006115 UniProtKB/TrEMBL
  ENSCAFG00845000749 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007759.3 UniProtKB/TrEMBL
  ENSCAFT00030008243.1 UniProtKB/TrEMBL
  ENSCAFT00040011396.1 UniProtKB/TrEMBL
  ENSCAFT00845001235 ENTREZGENE
  ENSCAFT00845001235.1 UniProtKB/TrEMBL
InterPro PLAC_motif_containing UniProtKB/TrEMBL
NCBI Gene CNFN ENTREZGENE
PANTHER CORNIFELIN UniProtKB/TrEMBL
  PTHR15907 UniProtKB/TrEMBL
Pfam PLAC8 UniProtKB/TrEMBL
UniProt A0A8C0KJE5 ENTREZGENE
  A0A8C0M6W0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MBH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SAD0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39394 ENTREZGENE