GPR4 (G protein-coupled receptor 4) - Rat Genome Database

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Gene: GPR4 (G protein-coupled receptor 4) Canis lupus familiaris
Analyze
Symbol: GPR4
Name: G protein-coupled receptor 4
RGD ID: 12072745
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN angiogenesis involved in wound healing (ortholog); G protein-coupled receptor signaling pathway (ortholog); glomerular mesangial cell development (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G-protein coupled receptor 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,963,001 - 109,974,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,447,845 - 109,459,640 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,496,036 - 110,507,845 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,496,054 - 110,506,310 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,171,544 - 110,183,332 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,805,926 - 109,817,699 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,675,080 - 110,686,875 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
GPR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,963,001 - 109,974,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,447,845 - 109,459,640 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,496,036 - 110,507,845 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,496,054 - 110,506,310 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,171,544 - 110,183,332 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,805,926 - 109,817,699 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,675,080 - 110,686,875 (+)NCBIUU_Cfam_GSD_1.0
GPR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,589,764 - 45,602,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,589,764 - 45,602,212 (-)EnsemblGRCh38hg38GRCh38
GRCh371946,093,022 - 46,105,470 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,784,865 - 50,787,557 (-)NCBINCBI36Build 36hg18NCBI36
Build 341950,784,864 - 50,787,557NCBI
Celera1942,899,136 - 42,911,570 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,522,224 - 42,534,658 (-)NCBIHuRef
CHM1_11946,096,300 - 46,108,733 (-)NCBICHM1_1
T2T-CHM13v2.01948,417,036 - 48,429,476 (-)NCBIT2T-CHM13v2.0
Gpr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,946,463 - 18,958,101 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,946,463 - 18,958,099 (+)EnsemblGRCm39 Ensembl
GRCm38719,212,538 - 19,224,176 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,212,538 - 19,224,174 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,797,887 - 19,809,525 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,371,060 - 18,382,698 (+)NCBIMGSCv36mm8
Celera716,634,236 - 16,637,031 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Gpr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,993,398 - 88,004,568 (+)NCBIGRCr8
mRatBN7.2178,865,376 - 78,877,126 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,865,409 - 78,876,599 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,264,234 - 84,265,722 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,821,703 - 92,823,191 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,019,316 - 86,020,804 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,125,639 - 80,136,786 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,135,391 - 80,136,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,392,318 - 81,403,269 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,586,541 - 78,588,029 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,664,651 - 78,666,140 (+)NCBI
Celera173,337,571 - 73,339,059 (+)NCBICelera
Cytogenetic Map1q21NCBI
Gpr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557486,494 - 87,582 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495557485,619 - 87,928 (-)NCBIChiLan1.0ChiLan1.0
GPR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,751,034 - 51,763,566 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,622,332 - 53,634,999 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,594,996 - 42,608,032 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,136,128 - 51,153,410 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,137,138 - 51,138,226 (-)Ensemblpanpan1.1panPan2
Gpr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,651,868 - 17,660,317 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,999,340 - 2,000,428 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,999,218 - 2,001,176 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,968,814 - 51,979,461 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,968,310 - 51,979,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GPR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,038,910 - 39,054,524 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,039,041 - 39,040,129 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,662,295 - 18,674,080 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,575,758 - 7,576,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,566,645 - 7,579,497 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPR4
126 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845009021   ⟹   ENSCAFP00845007113
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1110,496,054 - 110,506,310 (+)Ensembl
RefSeq Acc Id: XM_005616440   ⟹   XP_005616497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11109,963,001 - 109,974,798 (+)NCBI
Dog10K_Boxer_Tasha1109,447,845 - 109,459,640 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005616441   ⟹   XP_005616498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11109,963,966 - 109,974,798 (+)NCBI
Dog10K_Boxer_Tasha1109,449,026 - 109,459,640 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038467843   ⟹   XP_038323771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11110,171,544 - 110,183,332 (+)NCBI
RefSeq Acc Id: XM_038467844   ⟹   XP_038323772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11110,172,717 - 110,183,332 (+)NCBI
RefSeq Acc Id: XM_038528565   ⟹   XP_038384493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01110,675,080 - 110,686,875 (+)NCBI
RefSeq Acc Id: XM_038528566   ⟹   XP_038384494
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01110,676,257 - 110,686,875 (+)NCBI
RefSeq Acc Id: XM_038592843   ⟹   XP_038448771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01109,805,926 - 109,817,699 (+)NCBI
RefSeq Acc Id: XM_038592844   ⟹   XP_038448772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01109,807,093 - 109,817,699 (+)NCBI
RefSeq Acc Id: XM_038656646   ⟹   XP_038512574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01110,496,036 - 110,507,845 (+)NCBI
RefSeq Acc Id: XM_038656647   ⟹   XP_038512575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01110,497,224 - 110,507,845 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005616497   ⟸   XM_005616440
- UniProtKB: A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005616498   ⟸   XM_005616441
- UniProtKB: A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038323771   ⟸   XM_038467843
RefSeq Acc Id: XP_038323772   ⟸   XM_038467844
RefSeq Acc Id: XP_038448771   ⟸   XM_038592843
RefSeq Acc Id: XP_038448772   ⟸   XM_038592844
RefSeq Acc Id: XP_038512574   ⟸   XM_038656646
- UniProtKB: A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512575   ⟸   XM_038656647
- UniProtKB: A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384493   ⟸   XM_038528565
- UniProtKB: A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384494   ⟸   XM_038528566
- UniProtKB: A0A8C0KB37 (UniProtKB/TrEMBL),   A0A8C0S0P7 (UniProtKB/TrEMBL),   A0A8I3MW45 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845007113   ⟸   ENSCAFT00845009021
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000050631 UniProtKB/TrEMBL
  ENSCAFG00030003419 UniProtKB/TrEMBL
  ENSCAFG00040008510 UniProtKB/TrEMBL
  ENSCAFG00845005035 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000095131.1 UniProtKB/TrEMBL
  ENSCAFT00030006392.1 UniProtKB/TrEMBL
  ENSCAFT00040015882.1 UniProtKB/TrEMBL
  ENSCAFT00845009021 ENTREZGENE
  ENSCAFT00845009021.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GPR4_orph UniProtKB/TrEMBL
KEGG Report cfa:484440 UniProtKB/TrEMBL
NCBI Gene GPR4 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR 4 UniProtKB/TrEMBL
  LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  GPR4RECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0KB37 ENTREZGENE
  A0A8C0S0P7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MW45 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41435 ENTREZGENE