IFI35 (interferon induced protein 35) - Rat Genome Database

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Gene: IFI35 (interferon induced protein 35) Canis lupus familiaris
Analyze
Symbol: IFI35
Name: interferon induced protein 35
RGD ID: 12069567
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN immune system process (inferred); innate immune response (inferred); macrophage activation involved in immune response (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,050,438 - 20,061,346 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,050,438 - 20,061,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,512,038 - 19,522,948 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,768,845 - 20,779,755 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,768,851 - 20,779,732 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,553,944 - 19,564,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,820,685 - 19,831,593 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,922,745 - 19,933,656 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IFI35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,050,438 - 20,061,346 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,050,438 - 20,061,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,512,038 - 19,522,948 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,768,845 - 20,779,755 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,768,851 - 20,779,732 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,553,944 - 19,564,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,820,685 - 19,831,593 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,922,745 - 19,933,656 (-)NCBIUU_Cfam_GSD_1.0
IFI35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381743,006,784 - 43,014,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1743,006,740 - 43,014,456 (+)EnsemblGRCh38hg38GRCh38
GRCh371741,158,801 - 41,166,473 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,412,351 - 38,419,999 (+)NCBINCBI36Build 36hg18NCBI36
Build 341738,412,350 - 38,419,998NCBI
Celera1737,815,041 - 37,822,746 (+)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1736,924,506 - 36,932,236 (+)NCBIHuRef
CHM1_11741,394,259 - 41,402,019 (+)NCBICHM1_1
T2T-CHM13v2.01743,864,072 - 43,871,742 (+)NCBIT2T-CHM13v2.0
Ifi35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,339,238 - 101,349,527 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,339,233 - 101,349,524 (+)EnsemblGRCm39 Ensembl
GRCm3811101,448,412 - 101,458,701 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,448,407 - 101,458,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711101,309,726 - 101,320,015 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,264,571 - 101,274,552 (+)NCBIMGSCv36mm8
Celera11113,135,844 - 113,146,133 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.07NCBI
Ifi35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,881,270 - 86,889,523 (+)NCBIGRCr8
mRatBN7.21086,381,023 - 86,389,279 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,381,010 - 86,389,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,418,433 - 91,426,447 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,893,398 - 90,901,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,286,702 - 86,295,023 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,358,376 - 89,366,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,358,376 - 89,366,626 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,156,392 - 89,164,644 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,475,323 - 90,483,575 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,489,692 - 90,497,943 (+)NCBI
Celera1085,098,510 - 85,106,762 (+)NCBICelera
Cytogenetic Map10q31NCBI
Ifi35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,790,383 - 16,802,664 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,790,998 - 16,798,993 (+)NCBIChiLan1.0ChiLan1.0
IFI35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21921,977,994 - 21,985,622 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11723,867,276 - 23,874,824 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,310,106 - 14,317,648 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,539,625 - 14,544,931 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,539,625 - 14,544,931 (-)Ensemblpanpan1.1panPan2
Ifi35
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,364,845 - 19,367,164 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,708,071 - 17,713,492 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,707,997 - 17,710,294 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFI35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,879,387 - 19,890,314 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11219,879,386 - 19,890,330 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21219,991,296 - 20,002,226 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IFI35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,276,493 - 63,284,196 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,273,829 - 63,284,283 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,063,175 - 34,070,917 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ifi35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,260,476 - 1,262,080 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,260,476 - 1,268,015 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IFI35
61 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 21 6 6 6 4 6 10 3
Low 1 5 1 2 5 6 8 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000038918   ⟹   ENSCAFP00000034705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl920,050,438 - 20,061,319 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845011303   ⟹   ENSCAFP00845008821
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl920,768,851 - 20,779,732 (-)Ensembl
RefSeq Acc Id: XM_038485449   ⟹   XP_038341377
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1919,553,944 - 19,564,859 (-)NCBI
RefSeq Acc Id: XM_038547212   ⟹   XP_038403140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0919,922,745 - 19,933,656 (-)NCBI
RefSeq Acc Id: XM_038611178   ⟹   XP_038467106
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0919,820,685 - 19,831,593 (-)NCBI
RefSeq Acc Id: XM_038676367   ⟹   XP_038532295
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,768,845 - 20,779,755 (-)NCBI
RefSeq Acc Id: XM_548077   ⟹   XP_548077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,050,438 - 20,061,346 (-)NCBI
Dog10K_Boxer_Tasha919,512,038 - 19,522,948 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_548077   ⟸   XM_548077
- UniProtKB: A0A8C0RAJ1 (UniProtKB/TrEMBL),   A0A8I3RT92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000034705   ⟸   ENSCAFT00000038918
RefSeq Acc Id: XP_038341377   ⟸   XM_038485449
RefSeq Acc Id: XP_038467106   ⟸   XM_038611178
RefSeq Acc Id: XP_038532295   ⟸   XM_038676367
- UniProtKB: A0A8C0RAJ1 (UniProtKB/TrEMBL),   A0A8I3RT92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403140   ⟸   XM_038547212
- UniProtKB: A0A8C0RAJ1 (UniProtKB/TrEMBL),   A0A8I3RT92 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845008821   ⟸   ENSCAFT00845011303
Protein Domains
NID   Nmi/IFP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014624 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001845 UniProtKB/TrEMBL
  ENSCAFG00040020160 UniProtKB/TrEMBL
  ENSCAFG00845006373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000038918.4 UniProtKB/TrEMBL
  ENSCAFT00030003348.1 UniProtKB/TrEMBL
  ENSCAFT00040037253.1 UniProtKB/TrEMBL
  ENSCAFT00845011303 ENTREZGENE
  ENSCAFT00845011303.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nmi/IFP35_dom UniProtKB/TrEMBL
  Nmi/IFP35_N UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
KEGG Report cfa:490954 UniProtKB/TrEMBL
NCBI Gene IFI35 ENTREZGENE
PANTHER INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN UniProtKB/TrEMBL
  PTHR15225:SF1 UniProtKB/TrEMBL
Pfam IFP_35_N UniProtKB/TrEMBL
  NID UniProtKB/TrEMBL
UniProt A0A8C0RAJ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RT92 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41872 ENTREZGENE