CAPS (calcyphosine) - Rat Genome Database

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Gene: CAPS (calcyphosine) Canis lupus familiaris
Analyze
Symbol: CAPS
Name: calcyphosine
RGD ID: 12066143
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcyphosin; protein 5; thyroid protein p24; TPP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,175,986 - 54,177,889 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,175,986 - 54,177,889 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,919,783 - 53,921,392 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,827,470 - 54,829,079 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,827,468 - 54,833,760 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,893,876 - 53,895,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02054,342,752 - 54,344,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02054,572,907 - 54,574,519 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CAPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,175,986 - 54,177,889 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,175,986 - 54,177,889 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,919,783 - 53,921,392 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,827,470 - 54,829,079 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,827,468 - 54,833,760 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,893,876 - 53,895,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02054,342,752 - 54,344,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02054,572,907 - 54,574,519 (-)NCBIUU_Cfam_GSD_1.0
CAPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38195,914,254 - 5,916,211 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl195,912,339 - 5,916,211 (+)EnsemblGRCh38hg38GRCh38
GRCh37195,914,265 - 5,916,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36195,865,219 - 5,866,886 (+)NCBINCBI36Build 36hg18NCBI36
Build 34195,865,218 - 5,866,886NCBI
Celera195,853,155 - 5,855,184 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef195,673,686 - 5,675,715 (+)NCBIHuRef
CHM1_1195,914,445 - 5,916,474 (+)NCBICHM1_1
T2T-CHM13v2.0195,901,694 - 5,903,651 (+)NCBIT2T-CHM13v2.0
Tnfrsf23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,219,544 - 143,239,836 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,219,546 - 143,239,609 (-)EnsemblGRCm39 Ensembl
GRCm387143,665,807 - 143,686,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,665,809 - 143,685,872 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,851,712 - 150,871,777 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,475,197 - 143,495,262 (-)NCBIMGSCv36mm8
Celera7143,421,620 - 143,442,135 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.28NCBI
Caps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,630,871 - 1,632,758 (-)NCBIGRCr8
mRatBN7.291,544,597 - 1,545,631 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,544,719 - 1,545,647 (-)EnsemblmRatBN7.2 Ensembl
Cytogenetic Map9q11NCBI
Caps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554953,549,455 - 3,550,965 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554953,549,455 - 3,550,965 (-)NCBIChiLan1.0ChiLan1.0
CAPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22010,305,725 - 10,316,599 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,531,929 - 9,542,799 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0194,925,556 - 4,936,806 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1195,863,665 - 5,865,733 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl195,855,528 - 5,861,485 (+)Ensemblpanpan1.1panPan2
Caps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,437,397 - 214,438,987 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365883,393,024 - 3,398,215 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365883,395,859 - 3,398,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl273,123,191 - 73,124,916 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1273,122,784 - 73,124,979 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2273,688,741 - 73,690,473 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.165,529,604 - 5,546,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660812,484,185 - 2,507,922 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Caps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248284,311,790 - 4,314,524 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248284,311,650 - 4,314,781 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CAPS
22 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 4 4
Medium 7 12 6
Low 5 4 11 6 6 6 6 6
Below cutoff 1 6 8

Sequence


RefSeq Acc Id: ENSCAFT00000029761   ⟹   ENSCAFP00000027658
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2054,175,986 - 54,177,889 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021735   ⟹   ENSCAFP00845017092
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2054,827,468 - 54,833,760 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021759   ⟹   ENSCAFP00845017110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2054,827,468 - 54,829,158 (-)Ensembl
RefSeq Acc Id: NM_001003282   ⟹   NP_001003282
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12054,175,986 - 54,177,889 (-)NCBI
Dog10K_Boxer_Tasha2053,919,783 - 53,921,392 (-)NCBI
ROS_Cfam_1.02054,827,470 - 54,829,079 (-)NCBI
UMICH_Zoey_3.12053,893,876 - 53,895,482 (-)NCBI
UNSW_CanFamBas_1.02054,342,752 - 54,344,350 (-)NCBI
UU_Cfam_GSD_1.02054,572,907 - 54,574,519 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003282 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA32205 (Get FASTA)   NCBI Sequence Viewer  
  CAA32641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000027658.4
  ENSCAFP00000069391.1
  ENSCAFP00040040913.1
  ENSCAFP00805039538
  ENSCAFP00845017092.1
  ENSCAFP00845017110
  ENSCAFP00845017110.1
GenBank Protein P10463 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001003282   ⟸   NM_001003282
- UniProtKB: P10463 (UniProtKB/Swiss-Prot),   A0A8C0KZV0 (UniProtKB/TrEMBL),   A0A8I3NMQ2 (UniProtKB/TrEMBL),   A0A8P0PJ51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000027658   ⟸   ENSCAFT00000029761
RefSeq Acc Id: ENSCAFP00845017092   ⟸   ENSCAFT00845021735
RefSeq Acc Id: ENSCAFP00845017110   ⟸   ENSCAFT00845021759
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018746 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040025138 UniProtKB/Swiss-Prot
  ENSCAFG00805027842 UniProtKB/Swiss-Prot
  ENSCAFG00845012225 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029761.4 UniProtKB/Swiss-Prot
  ENSCAFT00000102875.1 UniProtKB/TrEMBL
  ENSCAFT00040046870.1 UniProtKB/Swiss-Prot
  ENSCAFT00805050463 UniProtKB/Swiss-Prot
  ENSCAFT00845021735.1 UniProtKB/TrEMBL
  ENSCAFT00845021759 ENTREZGENE
  ENSCAFT00845021759.1 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403965 UniProtKB/Swiss-Prot
NCBI Gene CAPS ENTREZGENE
PANTHER CALCYPHOSIN UniProtKB/Swiss-Prot
  CALCYPHOSIN UniProtKB/Swiss-Prot
  CALCYPHOSIN UniProtKB/TrEMBL
  CALCYPHOSIN UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0KZV0 ENTREZGENE
  A0A8I3NMQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PJ51 ENTREZGENE, UniProtKB/TrEMBL
  CAYP1_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:54265 ENTREZGENE