TMEM165 (transmembrane protein 165) - Rat Genome Database

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Gene: TMEM165 (transmembrane protein 165) Canis lupus familiaris
Analyze
Symbol: TMEM165
Name: transmembrane protein 165
RGD ID: 12065333
Description: ENCODES a protein that exhibits calcium ion transmembrane transporter activity (inferred); manganese ion transmembrane transporter activity (inferred); INVOLVED IN calcium ion transport (inferred); Golgi calcium ion homeostasis (inferred); Golgi calcium ion transport (inferred); ASSOCIATED WITH congenital disorder of glycosylation (ortholog); congenital disorder of glycosylation type IIk (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cis-Golgi network membrane (inferred); endosome membrane (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11347,658,408 - 47,683,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1347,658,330 - 47,682,866 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,615,826 - 47,640,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01348,269,540 - 48,294,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1348,269,177 - 48,293,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11347,944,501 - 47,969,326 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01347,472,885 - 47,498,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01348,421,927 - 48,446,757 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TMEM165
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11347,658,408 - 47,683,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1347,658,330 - 47,682,866 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,615,826 - 47,640,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01348,269,540 - 48,294,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1348,269,177 - 48,293,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11347,944,501 - 47,969,326 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01347,472,885 - 47,498,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01348,421,927 - 48,446,757 (+)NCBIUU_Cfam_GSD_1.0
TMEM165
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38455,395,957 - 55,453,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl455,395,957 - 55,453,397 (+)EnsemblGRCh38hg38GRCh38
GRCh37456,262,124 - 56,292,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36455,957,114 - 55,987,099 (+)NCBINCBI36Build 36hg18NCBI36
Celera453,763,917 - 53,794,196 (+)NCBICelera
Cytogenetic Map4q12NCBI
HuRef452,211,028 - 52,241,329 (+)NCBIHuRef
CHM1_1456,297,232 - 56,327,471 (+)NCBICHM1_1
T2T-CHM13v2.0458,884,101 - 58,941,541 (+)NCBIT2T-CHM13v2.0
Tmem165
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39576,331,727 - 76,357,091 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl576,331,727 - 76,357,092 (+)EnsemblGRCm39 Ensembl
GRCm38576,183,880 - 76,209,244 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl576,183,880 - 76,209,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv37576,612,905 - 76,638,269 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36577,258,725 - 77,284,019 (+)NCBIMGSCv36mm8
Celera573,455,356 - 73,480,717 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map540.56NCBI
Tmem165
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81432,347,688 - 32,372,916 (-)NCBIGRCr8
mRatBN7.21431,993,489 - 32,018,717 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,993,493 - 32,018,717 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1432,359,800 - 32,385,021 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01433,667,692 - 33,692,913 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01432,152,809 - 32,178,030 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01434,503,037 - 34,528,262 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1434,503,038 - 34,528,262 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01434,290,287 - 34,315,512 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41434,265,575 - 34,290,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11434,265,575 - 34,290,800 (-)NCBI
Celera1431,294,526 - 31,319,751 (-)NCBICelera
Cytogenetic Map14p11NCBI
Tmem165
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544715,538,958 - 15,543,892 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544715,538,958 - 15,543,885 (-)NCBIChiLan1.0ChiLan1.0
TMEM165
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2374,339,011 - 74,396,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1474,543,016 - 74,600,312 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0468,484,896 - 68,541,808 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1475,075,427 - 75,104,629 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl475,075,427 - 75,104,629 (-)Ensemblpanpan1.1panPan2
Tmem165
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528528,512,769 - 28,537,702 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648217,760,384 - 17,785,587 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648217,760,532 - 17,785,466 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM165
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl854,751,572 - 54,787,886 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1854,751,570 - 54,796,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2858,762,005 - 58,769,745 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM165
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1713,136,414 - 13,167,521 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl713,135,845 - 13,167,499 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606613,893,044 - 13,924,787 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem165
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476114,038,758 - 14,066,894 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476114,039,698 - 14,066,750 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM165
319 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 16 6 6 12 8 10 6
Low 6 6 6 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000003310   ⟹   ENSCAFP00000003073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1347,658,330 - 47,682,866 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000075364   ⟹   ENSCAFP00000066567
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1347,658,330 - 47,678,655 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000084466   ⟹   ENSCAFP00000045212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1347,658,693 - 47,682,866 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021876   ⟹   ENSCAFP00845017207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1348,269,177 - 48,293,716 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021921   ⟹   ENSCAFP00845017237
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1348,269,540 - 48,293,716 (+)Ensembl
RefSeq Acc Id: XM_038492842   ⟹   XP_038348770
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11347,944,501 - 47,969,326 (+)NCBI
RefSeq Acc Id: XM_038555079   ⟹   XP_038411007
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01348,421,927 - 48,446,757 (+)NCBI
RefSeq Acc Id: XM_038618957   ⟹   XP_038474885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01347,472,885 - 47,498,052 (+)NCBI
RefSeq Acc Id: XM_038684560   ⟹   XP_038540488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01348,269,540 - 48,294,369 (+)NCBI
RefSeq Acc Id: XM_532375   ⟹   XP_532375
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11347,658,408 - 47,683,519 (+)NCBI
Dog10K_Boxer_Tasha1347,615,826 - 47,640,649 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_532375   ⟸   XM_532375
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JGC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000045212   ⟸   ENSCAFT00000084466
RefSeq Acc Id: ENSCAFP00000003073   ⟸   ENSCAFT00000003310
RefSeq Acc Id: ENSCAFP00000066567   ⟸   ENSCAFT00000075364
RefSeq Acc Id: XP_038348770   ⟸   XM_038492842
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474885   ⟸   XM_038618957
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038540488   ⟸   XM_038684560
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038411007   ⟸   XM_038555079
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JGC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845017207   ⟸   ENSCAFT00845021876
RefSeq Acc Id: ENSCAFP00845017237   ⟸   ENSCAFT00845021921

Promoters
RGD ID:13685657
Promoter ID:EPDNEW_C3724
Type:multiple initiation site
Name:TMEM165_1
Description:transmembrane protein 165
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11347,658,472 - 47,658,532EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002094 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040016139 UniProtKB/TrEMBL
  ENSCAFG00845012298 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003310.5 UniProtKB/TrEMBL
  ENSCAFT00000084466.2 UniProtKB/TrEMBL
  ENSCAFT00040029732.1 UniProtKB/TrEMBL
  ENSCAFT00040029775.1 UniProtKB/TrEMBL
  ENSCAFT00845021876.1 UniProtKB/TrEMBL
  ENSCAFT00845021921.1 UniProtKB/TrEMBL
InterPro Gdt1 UniProtKB/TrEMBL
  GDT1-like_CS UniProtKB/TrEMBL
NCBI Gene TMEM165 ENTREZGENE
PANTHER PTHR12608 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 165 UniProtKB/TrEMBL
Pfam UPF0016 UniProtKB/TrEMBL
PROSITE UPF0016 UniProtKB/TrEMBL
UniProt A0A8C0JGC8 ENTREZGENE
  A0A8C0SUY2_CANLF UniProtKB/TrEMBL
  A0A8C0SV17_CANLF UniProtKB/TrEMBL
  A0A8I3NM24_CANLF UniProtKB/TrEMBL
  A0A8I3RX06_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0N568 UniProtKB/TrEMBL
  A0A8P0NVK8 UniProtKB/TrEMBL
VGNC ID VGNC:47492 ENTREZGENE