PEAK3 (PEAK family member 3) - Rat Genome Database

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Gene: PEAK3 (PEAK family member 3) Canis lupus familiaris
Analyze
Symbol: PEAK3
Name: PEAK family member 3
RGD ID: 12056258
Description: ENCODES a protein that exhibits obsolete protein self-association (inferred); protein kinase activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of cell shape (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); progressive myoclonus epilepsy 9 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C20H19orf35; chromosome 20 open reading frame, human C19orf35; putative uncharacterized protein C19orf35 homolog
RGD Orthologs
Human
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,763,966 - 56,768,210 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,762,791 - 56,767,223 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,559,083 - 56,563,401 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02057,496,875 - 57,501,193 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,496,775 - 57,501,207 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12056,548,934 - 56,553,251 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,034,134 - 57,038,431 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,234,519 - 57,238,837 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PEAK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,763,966 - 56,768,210 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,762,791 - 56,767,223 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,559,083 - 56,563,401 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02057,496,875 - 57,501,193 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,496,775 - 57,501,207 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12056,548,934 - 56,553,251 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,034,134 - 57,038,431 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,234,519 - 57,238,837 (+)NCBIUU_Cfam_GSD_1.0
PEAK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,274,631 - 2,282,175 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,274,631 - 2,282,175 (-)EnsemblGRCh38hg38GRCh38
GRCh37192,274,630 - 2,282,174 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,225,631 - 2,233,175 (-)NCBINCBI36Build 36hg18NCBI36
Build 34192,225,630 - 2,233,175NCBI
Celera192,208,806 - 2,216,106 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,045,610 - 2,053,398 (-)NCBIHuRef
CHM1_1192,274,231 - 2,281,769 (-)NCBICHM1_1
T2T-CHM13v2.0192,248,275 - 2,255,818 (-)NCBIT2T-CHM13v2.0
Peak3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554955,866,204 - 5,869,808 (+)NCBIChiLan1.0ChiLan1.0
PEAK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2206,656,370 - 6,665,668 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,885,717 - 5,895,014 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,284,060 - 1,292,131 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,256,726 - 2,262,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,256,726 - 2,262,586 (-)Ensemblpanpan1.1panPan2
Peak3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,466,877 - 216,472,781 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365881,362,009 - 1,367,391 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEAK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,285,882 - 76,291,290 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,285,163 - 76,291,295 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,847,052 - 76,853,089 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEAK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,066,731 - 2,074,189 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl62,067,476 - 2,072,727 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660816,637,374 - 6,643,994 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Peak3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248286,612,201 - 6,615,888 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PEAK3
90 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 4 2 6 2 6 7 5
Below cutoff 4 4 17 4 4 4 8 7 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038429225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038429226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038429227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_849910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000045252   ⟹   ENSCAFP00000039834
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2056,762,791 - 56,767,223 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021940   ⟹   ENSCAFP00845017252
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2057,496,775 - 57,501,207 (+)Ensembl
RefSeq Acc Id: XM_038429225   ⟹   XP_038285153
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02057,496,875 - 57,501,193 (+)NCBI
RefSeq Acc Id: XM_038429226   ⟹   XP_038285154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02057,496,896 - 57,501,193 (+)NCBI
RefSeq Acc Id: XM_038429227   ⟹   XP_038285155
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02057,496,920 - 57,501,193 (+)NCBI
RefSeq Acc Id: XM_038455748   ⟹   XP_038311676
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2056,559,083 - 56,563,401 (+)NCBI
RefSeq Acc Id: XM_038455749   ⟹   XP_038311677
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2056,559,104 - 56,563,401 (+)NCBI
RefSeq Acc Id: XM_038455750   ⟹   XP_038311678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2056,559,128 - 56,563,401 (+)NCBI
RefSeq Acc Id: XM_038504758   ⟹   XP_038360686
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12056,548,934 - 56,553,251 (+)NCBI
RefSeq Acc Id: XM_038504759   ⟹   XP_038360687
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12056,548,955 - 56,553,251 (+)NCBI
RefSeq Acc Id: XM_038504760   ⟹   XP_038360688
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12056,548,979 - 56,553,251 (+)NCBI
RefSeq Acc Id: XM_038567898   ⟹   XP_038423826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02057,234,519 - 57,238,837 (+)NCBI
RefSeq Acc Id: XM_038567899   ⟹   XP_038423827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02057,234,540 - 57,238,837 (+)NCBI
RefSeq Acc Id: XM_038567900   ⟹   XP_038423828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02057,234,564 - 57,238,837 (+)NCBI
RefSeq Acc Id: XM_038632021   ⟹   XP_038487949
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02057,034,134 - 57,038,431 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000039834   ⟸   ENSCAFT00000045252
RefSeq Acc Id: XP_038360686   ⟸   XM_038504758
RefSeq Acc Id: XP_038360687   ⟸   XM_038504759
RefSeq Acc Id: XP_038360688   ⟸   XM_038504760
RefSeq Acc Id: XP_038487949   ⟸   XM_038632021
RefSeq Acc Id: XP_038285153   ⟸   XM_038429225
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038285154   ⟸   XM_038429226
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038285155   ⟸   XM_038429227
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311676   ⟸   XM_038455748
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311677   ⟸   XM_038455749
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311678   ⟸   XM_038455750
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423826   ⟸   XM_038567898
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423827   ⟸   XM_038567899
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423828   ⟸   XM_038567900
- UniProtKB: A0A8C0SB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845017252   ⟸   ENSCAFT00845021940


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000024487 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040011735 UniProtKB/TrEMBL
  ENSCAFG00845012346 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000045252.4 UniProtKB/TrEMBL
  ENSCAFT00040021637.1 UniProtKB/TrEMBL
  ENSCAFT00845021940.1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
NCBI Gene C20H19orf35 ENTREZGENE
PANTHER PROTEIN PEAK3 UniProtKB/TrEMBL
  SERINE/THREONINE PROTEIN KINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C0SB84 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NKZ4_CANLF UniProtKB/TrEMBL
  A0A8P0NR51_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:81918 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-08 PEAK3  PEAK family member 3  C20H19orf35  chromosome 20 open reading frame, human C19orf35  Symbol and/or name change 5135510 APPROVED