CA2 (carbonic anhydrase 2) - Rat Genome Database

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Gene: CA2 (carbonic anhydrase 2) Canis lupus familiaris
Analyze
Symbol: CA2
Name: carbonic anhydrase 2
RGD ID: 12051818
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN carbon dioxide transport (ortholog); cellular response to fluid shear stress (ortholog); kidney development (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); autism spectrum disorder (ortholog); FOUND IN apical part of cell (ortholog); axon (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: INFERRED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,959,225 - 31,975,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2932,190,440 - 32,197,007 (+)NCBI
ROS_Cfam_1.02932,108,070 - 32,124,176 (+)NCBI
UMICH_Zoey_3.12932,159,433 - 32,175,512 (+)NCBI
UNSW_CanFamBas_1.02932,180,668 - 32,196,793 (+)NCBI
UU_Cfam_GSD_1.02932,567,770 - 32,583,867 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:19874279   PMID:19959906  


Genomics

Comparative Map Data
CA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,959,225 - 31,975,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2932,190,440 - 32,197,007 (+)NCBI
ROS_Cfam_1.02932,108,070 - 32,124,176 (+)NCBI
UMICH_Zoey_3.12932,159,433 - 32,175,512 (+)NCBI
UNSW_CanFamBas_1.02932,180,668 - 32,196,793 (+)NCBI
UU_Cfam_GSD_1.02932,567,770 - 32,583,867 (+)NCBI
CA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl885,463,968 - 85,481,493 (+)EnsemblGRCh38hg38GRCh38
GRCh38885,464,007 - 85,481,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37886,376,236 - 86,393,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,563,383 - 86,580,973 (+)NCBINCBI36hg18NCBI36
Build 34886,563,497 - 86,580,973NCBI
Celera882,381,194 - 82,398,781 (+)NCBI
Cytogenetic Map8q21.2NCBI
HuRef881,870,322 - 81,887,902 (+)NCBIHuRef
CHM1_1886,427,817 - 86,445,411 (+)NCBICHM1_1
Car2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,951,329 - 14,965,830 (+)NCBIGRCm39mm39
GRCm39 Ensembl314,951,333 - 14,965,830 (+)Ensembl
GRCm38314,886,269 - 14,900,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,886,273 - 14,900,770 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,886,426 - 14,900,770 (+)NCBIGRCm37mm9NCBIm37
MGSCv36314,863,469 - 14,877,513 (+)NCBImm8
Celera314,899,001 - 14,912,886 (+)NCBICelera
Cytogenetic Map3A1NCBI
cM Map33.23NCBI
Car2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2286,741,625 - 86,756,766 (-)NCBI
Rnor_6.0 Ensembl288,097,720 - 88,113,029 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0288,097,740 - 88,112,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02107,871,654 - 107,886,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,077,095 - 88,092,223 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1288,022,060 - 88,037,185 (-)NCBI
Celera282,339,410 - 82,354,537 (-)NCBICelera
Cytogenetic Map2q23NCBI
Ca2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,386,087 - 3,402,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,388,110 - 3,402,798 (+)NCBIChiLan1.0ChiLan1.0
CA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1883,601,163 - 83,618,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl883,597,440 - 83,632,580 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0881,991,037 - 82,009,010 (+)NCBIMhudiblu_PPA_v0panPan3
Ca2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,413,843 - 47,429,881 (-)NCBI
SpeTri2.0NW_004936544362,591 - 379,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,193,755 - 51,211,259 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,194,686 - 51,211,436 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,157,606 - 56,174,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,830,963 - 80,848,245 (+)NCBI
ChlSab1.1 Ensembl880,830,939 - 80,848,707 (+)Ensembl
Ca2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247446,168,030 - 6,183,407 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000013785   ⟹   ENSCAFP00000012748
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2931,935,192 - 31,945,585 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000013799   ⟹   ENSCAFP00000012762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2931,959,177 - 31,975,309 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080967   ⟹   ENSCAFP00000045502
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2931,959,225 - 31,975,309 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000082253   ⟹   ENSCAFP00000053489
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2931,959,177 - 31,980,579 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000082360   ⟹   ENSCAFP00000043886
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2931,935,172 - 31,975,309 (+)Ensembl
RefSeq Acc Id: NM_001145170   ⟹   NP_001138642
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12931,959,225 - 31,975,309 (+)NCBI
Dog10K_Boxer_Tasha2932,190,440 - 32,197,007 (+)NCBI
ROS_Cfam_1.02932,108,070 - 32,124,176 (+)NCBI
UMICH_Zoey_3.12932,159,433 - 32,175,512 (+)NCBI
UNSW_CanFamBas_1.02932,180,668 - 32,196,793 (+)NCBI
UU_Cfam_GSD_1.02932,567,770 - 32,583,867 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001138642 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001138642   ⟸   NM_001145170
- UniProtKB: F1PDY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000012748   ⟸   ENSCAFT00000013785
RefSeq Acc Id: ENSCAFP00000012762   ⟸   ENSCAFT00000013799
RefSeq Acc Id: ENSCAFP00000053489   ⟸   ENSCAFT00000082253
RefSeq Acc Id: ENSCAFP00000043886   ⟸   ENSCAFT00000082360
RefSeq Acc Id: ENSCAFP00000045502   ⟸   ENSCAFT00000080967
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:13688444
Promoter ID:EPDNEW_C6514
Type:multiple initiation site
Name:CA2_1
Description:carbonic anhydrase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12931,959,204 - 31,959,264EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025202 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000012762 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000043886 UniProtKB/TrEMBL
  ENSCAFP00000045502 UniProtKB/TrEMBL
  ENSCAFP00000053489 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013799 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFT00000080967 UniProtKB/TrEMBL
  ENSCAFT00000082253 UniProtKB/TrEMBL
  ENSCAFT00000082360 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_CA3 UniProtKB/TrEMBL
NCBI Gene CA2 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF127 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A5F4BSH6_CANLF UniProtKB/TrEMBL
  A0A5F4BUI1_CANLF UniProtKB/TrEMBL
  A0A5F4CJB2_CANLF UniProtKB/TrEMBL
  F1PDY8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38610 ENTREZGENE