CA4 (carbonic anhydrase 4) - Rat Genome Database

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Gene: CA4 (carbonic anhydrase 4) Canis lupus familiaris
Analyze
Symbol: CA4
Name: carbonic anhydrase 4
RGD ID: 12050290
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN animal organ development (ortholog); response to drug (ortholog); response to steroid hormone (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); fundus dystrophy (ortholog); retinitis pigmentosa (ortholog); FOUND IN anchored component of plasma membrane (ortholog); apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,327,919 - 36,337,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,327,969 - 36,337,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha935,555,114 - 35,563,663 (-)NCBI
ROS_Cfam_1.0937,140,849 - 37,149,372 (-)NCBI
UMICH_Zoey_3.1935,919,574 - 35,928,095 (-)NCBI
UNSW_CanFamBas_1.0936,206,744 - 36,215,265 (-)NCBI
UU_Cfam_GSD_1.0936,294,940 - 36,303,505 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:19959906  


Genomics

Comparative Map Data
CA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,327,919 - 36,337,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,327,969 - 36,337,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha935,555,114 - 35,563,663 (-)NCBI
ROS_Cfam_1.0937,140,849 - 37,149,372 (-)NCBI
UMICH_Zoey_3.1935,919,574 - 35,928,095 (-)NCBI
UNSW_CanFamBas_1.0936,206,744 - 36,215,265 (-)NCBI
UU_Cfam_GSD_1.0936,294,940 - 36,303,505 (-)NCBI
CA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1760,149,942 - 60,170,899 (+)EnsemblGRCh38hg38GRCh38
GRCh381760,149,942 - 60,179,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371758,227,334 - 58,256,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,582,131 - 55,591,686 (+)NCBINCBI36hg18NCBI36
Build 341755,582,130 - 55,591,686NCBI
Celera1754,687,198 - 54,696,791 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,598,240 - 53,607,844 (+)NCBIHuRef
CHM1_11758,291,334 - 58,300,936 (+)NCBICHM1_1
Car4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,848,580 - 84,856,880 (+)NCBIGRCm39mm39
GRCm39 Ensembl1184,848,612 - 84,856,870 (+)Ensembl
GRCm381184,957,754 - 84,966,054 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,957,786 - 84,966,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv371184,771,256 - 84,779,556 (+)NCBIGRCm37mm9NCBIm37
MGSCv361184,774,038 - 84,782,239 (+)NCBImm8
Celera1194,577,982 - 94,586,281 (+)NCBICelera
Cytogenetic Map11CNCBI
Ca4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21069,827,945 - 69,836,501 (+)NCBI
Rnor_6.0 Ensembl1072,272,248 - 72,281,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01072,272,286 - 72,281,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01072,173,022 - 72,188,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,229,211 - 73,237,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,243,580 - 73,252,077 (+)NCBI
Celera1068,755,736 - 68,764,294 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ca4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554511,486,010 - 1,494,084 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554511,485,939 - 1,493,249 (+)NCBIChiLan1.0ChiLan1.0
CA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v01754,236,114 - 54,258,638 (+)NCBIMhudiblu_PPA_v0panPan3
Ca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,301,294 - 35,310,173 (-)NCBI
SpeTri2.0NW_0049364901,764,845 - 1,773,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1237,962,943 - 37,972,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11237,962,951 - 37,972,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21239,632,792 - 39,642,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11631,369,238 - 31,379,366 (+)NCBI
Ca4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248713,462,577 - 3,469,978 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 3 1 1 1 3 6 5 6
Low 19 5 5 5 3 6 6 8 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005624763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022423259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038486176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038486177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038486178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038677207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038677208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038677209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_537711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM253749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000028280   ⟹   ENSCAFP00000026299
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl936,327,969 - 36,336,836 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000076651   ⟹   ENSCAFP00000060847
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl936,327,969 - 36,337,088 (-)Ensembl
RefSeq Acc Id: XM_005624763   ⟹   XP_005624820
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1936,327,919 - 36,334,601 (-)NCBI
Dog10K_Boxer_Tasha935,555,114 - 35,561,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022423259   ⟹   XP_022278967
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1936,328,801 - 36,337,103 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038486176   ⟹   XP_038342104
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1935,919,574 - 35,925,918 (-)NCBI
RefSeq Acc Id: XM_038486177   ⟹   XP_038342105
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1935,919,574 - 35,928,095 (-)NCBI
RefSeq Acc Id: XM_038486178   ⟹   XP_038342106
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1935,920,157 - 35,925,934 (-)NCBI
RefSeq Acc Id: XM_038547994   ⟹   XP_038403922
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0936,294,940 - 36,303,503 (-)NCBI
RefSeq Acc Id: XM_038547995   ⟹   XP_038403923
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0936,294,940 - 36,301,314 (-)NCBI
RefSeq Acc Id: XM_038547996   ⟹   XP_038403924
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0936,295,529 - 36,303,505 (-)NCBI
RefSeq Acc Id: XM_038608580   ⟹   XP_038464508
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha935,555,700 - 35,563,663 (-)NCBI
RefSeq Acc Id: XM_038611961   ⟹   XP_038467889
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0936,206,744 - 36,215,263 (-)NCBI
RefSeq Acc Id: XM_038611962   ⟹   XP_038467890
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0936,206,744 - 36,213,087 (-)NCBI
RefSeq Acc Id: XM_038611963   ⟹   XP_038467891
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0936,207,317 - 36,215,265 (-)NCBI
RefSeq Acc Id: XM_038677207   ⟹   XP_038533135
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0937,140,849 - 37,147,189 (-)NCBI
RefSeq Acc Id: XM_038677208   ⟹   XP_038533136
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0937,140,849 - 37,149,372 (-)NCBI
RefSeq Acc Id: XM_038677209   ⟹   XP_038533137
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0937,141,426 - 37,147,204 (-)NCBI
RefSeq Acc Id: XM_537711   ⟹   XP_537711
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1936,327,919 - 36,336,754 (-)NCBI
Dog10K_Boxer_Tasha935,555,114 - 35,563,661 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_537711   ⟸   XM_537711
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005624820   ⟸   XM_005624763
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_022278967   ⟸   XM_022423259
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000026299   ⟸   ENSCAFT00000028280
RefSeq Acc Id: ENSCAFP00000060847   ⟸   ENSCAFT00000076651
RefSeq Acc Id: XP_038342105   ⟸   XM_038486177
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038342104   ⟸   XM_038486176
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342106   ⟸   XM_038486178
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038467889   ⟸   XM_038611961
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038467890   ⟸   XM_038611962
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038467891   ⟸   XM_038611963
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038533136   ⟸   XM_038677208
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038533135   ⟸   XM_038677207
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038533137   ⟸   XM_038677209
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038464508   ⟸   XM_038608580
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038403922   ⟸   XM_038547994
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038403923   ⟸   XM_038547995
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038403924   ⟸   XM_038547996
- Peptide Label: isoform X7
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:13684630
Promoter ID:EPDNEW_C2698
Type:multiple initiation site
Name:CA4_1
Description:carbonic anhydrase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1936,336,729 - 36,336,789EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017829 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000026299 UniProtKB/TrEMBL
  ENSCAFP00000060847 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000028280 UniProtKB/TrEMBL
  ENSCAFT00000076651 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA4/CA15 UniProtKB/TrEMBL
  Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_CA4 UniProtKB/TrEMBL
NCBI Gene CA4 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF95 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A5F4D507_CANLF UniProtKB/TrEMBL
  E1UGY9_CANLF UniProtKB/TrEMBL
  E2RBS1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38612 ENTREZGENE