PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1 like 1)

Gene: PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1 like 1) Pan paniscus

Analyze

Symbol:

PRPS1L1

Name:

phosphoribosyl pyrophosphate synthetase 1 like 1

RGD ID:

12048621

Description:

INVOLVED IN male gonad development (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

phosphoribosyl pyrophosphate synthetase 1-like 1; ribose-phosphate pyrophosphokinase 3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	22,859,141 - 22,860,249 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	71,183,865 - 71,184,973 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	18,680,579 - 18,681,655 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	18,006,809 - 18,007,885 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

male gonad development (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PRPS1L1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	22,859,141 - 22,860,249 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	71,183,865 - 71,184,973 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	18,680,579 - 18,681,655 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	18,006,809 - 18,007,885 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

PRPS1L1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	18,026,770 - 18,027,846 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	18,026,770 - 18,027,846 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	18,066,393 - 18,067,469 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	18,032,922 - 18,034,011 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	18,046,381 - 18,047,465 (-)	NCBI		Celera
Cytogenetic Map	7	p21.1	NCBI
HuRef	7	17,951,884 - 17,952,968 (-)	NCBI		HuRef
CHM1_1	7	18,067,488 - 18,068,577 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	18,156,457 - 18,157,533 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	18,119,717 - 18,120,801 (-)	NCBI

Prps1l1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	35,034,760 - 35,036,435 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	35,034,760 - 35,036,435 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	34,984,761 - 34,986,436 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	34,984,761 - 34,986,436 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	35,669,433 - 35,671,108 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	35,569,833 - 35,571,508 (+)	NCBI		MGSCv36	mm8
Celera	12	36,410,649 - 36,412,324 (+)	NCBI		Celera
Cytogenetic Map	12	A3	NCBI
cM Map	12	15.64	NCBI

Prps1l1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	57,412,331 - 57,414,021 (+)	NCBI		GRCr8
mRatBN7.2	6	51,684,960 - 51,686,650 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	51,684,948 - 51,687,291 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	51,969,122 - 51,970,812 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	52,284,060 - 52,285,750 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	51,740,499 - 51,742,189 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	54,417,903 - 54,419,593 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	54,417,903 - 54,419,593 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	64,038,717 - 64,040,407 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	53,652,048 - 53,653,738 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	53,655,288 - 53,656,268 (+)	NCBI
Celera	6	50,843,329 - 50,845,019 (+)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

Prps1l1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955410	20,987,289 - 20,988,852 (-)	NCBI	ChiLan1.0	ChiLan1.0

Prps1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	76,657,634 - 76,658,744 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936546	4,332,773 - 4,333,738 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRPS1L1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	87,163,252 - 87,164,208 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	87,161,863 - 87,164,314 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	96,258,718 - 96,259,873 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRPS1L1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	40,120,251 - 40,121,975 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	40,120,963 - 40,121,919 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	64,405,873 - 64,407,128 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prps1l1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624739	12,406,278 - 12,407,234 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624739	12,406,148 - 12,407,861 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003825025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_003825025 ⟹ XP_003825073

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	22,859,141 - 22,860,249 (-)	NCBI
NHGRI_mPanPan1	7	71,183,865 - 71,184,973 (-)	NCBI
Mhudiblu_PPA_v0	7	18,680,579 - 18,681,655 (-)	NCBI
PanPan1.1	7	18,006,809 - 18,007,885 (-)	NCBI

Sequence:

show sequence

GTCTGTGCTTCACTTCCGTTCCAGCCTCAGCGGCAGCTGGATCGCTCGACGGAGTGCCTCTGGT
AGTTGGCCAAGATGCCGAATATCAAAATCTTCAGCGGCAGCTCCCACCAGGACTTATCCCAGAA
AATTGCTGACCGCCTGGGCCTGGAGCTAGGCAAGGTGGTGACTAAGAAATTCAGCAACCAGGAG
ACCTGCGTGGAAATTGATGAGAGTGTGCGTGGAGAGGATGTCTACATCGTTCAGAGTGGTTGTG
GCGAAATCAACGACAGTCTAATGGAGCTTTTGATCATGATTAATGCCTGCAAGATTGCTTCAGC
TAGCCGAGTTACTGCAGTCATCCCATGCTTCCCTTATGCCCGACAGGATAAGAAGGATAAGAGC
CGGGCCCCAATCTCTGCCAAGCTTGTTGCAAATATGCTCTCTATAGCAGGTGCGGATCATATCA
TCACCATGGACCTACATGCTTCTCAAATTCAGGGCTTTTTTGATATCCCAGTAGACAACTTGTA
TGCAGAGCCCACTGTCCTGAGGTGGATAAGGGAGAATATCTCTGAGTGGAAGAACTGCATTATT
GTCTCGCCAGATGCTGGTGGAGCTAAAAGAGTGACCTCCATTGCAGACCAGTTGAATGTGGACT
TTGCTTTGATTCATAAAGAACAGAAGAAGGCCAATGAAGTGGACTGCATGGTGCTAGTGGGAGA
TGTGAATGATCGTGTGGCTATCCTTGTAGATGACATGGCAGACACTTGTGGTACAATCTGCCTC
GCAGCTGACAAACTTCTCTCAGCTGGAGCAACCAGAGTTTATGCTATTTTGACTCATGGAATCT
TTTCTGGCCCAGCCATTTCTCGCATCAACACTGCATGCTTTGAAGCAGTGGTAGTCACCAATAC
CATACCTCAAGATGATAACATGAAGCATTGCTCCAAAATACGAGTAATTGACATCTCCATGATC
CTTGCAGAAGCCATAAGGAGAACTCATAATGGGGAATCTGTTTCCTACCTGTTCAGCCATGTTC
CTTTATAACAGAATAACTTCTAGGTTATGCTATTTTAAAATAAAATAAGATTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003825073	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_003825073 ⟸ XM_003825025

- Sequence:

show sequence

MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEIN
DSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSIAGADHIITMD
LHASQIQGFFDIPVDNLYAEPTVLRWIRENISEWKNCIIVSPDAGGAKRVTSIADQLNVDFALI
HKEQKKANEVDCMVLVGDVNDRVAILVDDMADTCGTICLAADKLLSAGATRVYAILTHGIFSGP
AISRINTACFEAVVVTNTIPQDDNMKHCSKIRVIDISMILAEAIRRTHNGESVSYLFSHVPL

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000000060	ENTREZGENE
NCBI Gene	PRPS1L1	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-02-26	PRPS1L1	phosphoribosyl pyrophosphate synthetase 1 like 1		phosphoribosyl pyrophosphate synthetase 1-like 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - SMPDB