PHYH (phytanoyl-CoA 2-hydroxylase) - Rat Genome Database

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Gene: PHYH (phytanoyl-CoA 2-hydroxylase) Pan paniscus
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Symbol: PHYH
Name: phytanoyl-CoA 2-hydroxylase
RGD ID: 12038570
Description: ENCODES a protein that exhibits phytanoyl-CoA dioxygenase activity (ortholog); INVOLVED IN 2-oxobutyrate catabolic process (ortholog); fatty acid alpha-oxidation (ortholog); PARTICIPATES IN phytanic acid degradation pathway; Refsum disease pathway; ASSOCIATED WITH Adult Refsum Disease, 1 (ortholog); Familial Hypophosphatemic Rickets (ortholog); fundus dystrophy (ortholog); FOUND IN peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100981160; phytanoyl-CoA dioxygenase, peroxisomal; uncharacterized LOC100981160
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,798,371 - 25,822,011 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,803,696 - 25,826,001 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,277,804 - 13,300,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,250,722 - 13,634,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,251,223 - 13,636,018 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PHYH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,798,371 - 25,822,011 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,803,696 - 25,826,001 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,277,804 - 13,300,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,250,722 - 13,634,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,251,223 - 13,636,018 (-)Ensemblpanpan1.1panPan2
PHYH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,277,799 - 13,300,064 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,277,796 - 13,302,412 (-)EnsemblGRCh38hg38GRCh38
GRCh371013,319,799 - 13,342,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,359,802 - 13,382,136 (-)NCBINCBI36Build 36hg18NCBI36
Build 341013,359,805 - 13,382,107NCBI
Celera1013,246,935 - 13,269,237 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,232,668 - 13,254,996 (-)NCBIHuRef
CHM1_11013,319,709 - 13,342,691 (-)NCBICHM1_1
T2T-CHM13v2.01013,290,862 - 13,313,116 (-)NCBIT2T-CHM13v2.0
Phyh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,923,807 - 4,943,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,923,830 - 4,943,541 (+)EnsemblGRCm39 Ensembl
GRCm3824,918,996 - 4,938,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,919,019 - 4,938,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv3724,840,042 - 4,859,789 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3624,836,303 - 4,855,996 (+)NCBIMGSCv36mm8
Celera24,874,084 - 4,893,837 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map23.06NCBI
Phyh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,238,747 - 78,255,645 (-)NCBIGRCr8
mRatBN7.21773,329,461 - 73,346,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,329,082 - 73,346,409 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1776,834,020 - 76,851,123 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,658,833 - 80,675,645 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,709,804 - 74,727,044 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,287,580 - 77,304,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,287,188 - 77,304,530 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01778,953,400 - 78,970,299 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,418,173 - 84,435,073 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,429,005 - 84,445,906 (-)NCBI
Celera1772,770,062 - 72,786,946 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Phyh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,238,622 - 1,250,736 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554621,238,622 - 1,250,731 (-)NCBIChiLan1.0ChiLan1.0
LOC478000
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1223,185,901 - 23,206,719 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,185,782 - 23,253,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha220,243,502 - 20,263,391 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0223,491,323 - 23,512,130 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl223,491,168 - 23,619,903 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0221,525,646 - 21,546,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,153,837 - 22,174,674 (+)NCBIUU_Cfam_GSD_1.0
PHYH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,404,293 - 48,423,973 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,404,298 - 48,423,978 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PHYH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,309,059 - 13,331,606 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,308,951 - 13,331,504 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605118,841,615 - 18,862,691 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phyh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248055,801,392 - 5,813,696 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000061701   ⟹   ENSPPAP00000038793
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1013,251,223 - 13,636,018 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000061706   ⟹   ENSPPAP00000038797
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1013,251,223 - 13,634,056 (-)Ensembl
RefSeq Acc Id: XM_003806764   ⟹   XP_003806812
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2825,798,371 - 25,820,657 (-)NCBI
NHGRI_mPanPan11025,803,696 - 25,826,001 (-)NCBI
Mhudiblu_PPA_v01013,277,804 - 13,300,115 (-)NCBI
PanPan1.11013,250,722 - 13,634,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024930484   ⟹   XP_024786252
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2825,798,371 - 25,820,353 (-)NCBI
NHGRI_mPanPan11025,803,696 - 25,825,835 (-)NCBI
Mhudiblu_PPA_v01013,277,804 - 13,299,940 (-)NCBI
PanPan1.11013,250,722 - 13,633,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063607262   ⟹   XP_063463332
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2825,798,371 - 25,822,011 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003806812 (Get FASTA)   NCBI Sequence Viewer  
  XP_024786252 (Get FASTA)   NCBI Sequence Viewer  
  XP_063463332 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADI44278 (Get FASTA)   NCBI Sequence Viewer  
  ADI44288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038793.1
  ENSPPAP00000038797
  ENSPPAP00000038797.1
RefSeq Acc Id: XP_003806812   ⟸   XM_003806764
- Peptide Label: isoform X1
- UniProtKB: D7SD73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024786252   ⟸   XM_024930484
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000038797   ⟸   ENSPPAT00000061706
RefSeq Acc Id: ENSPPAP00000038793   ⟸   ENSPPAT00000061701
RefSeq Acc Id: XP_063463332   ⟸   XM_063607262
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042110 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061701.1 UniProtKB/TrEMBL
  ENSPPAT00000061706.1 UniProtKB/TrEMBL
Gene3D-CATH q2cbj1_9rhob like domain UniProtKB/TrEMBL
InterPro PhyH UniProtKB/TrEMBL
  Phytyl_CoA_dOase UniProtKB/TrEMBL
NCBI Gene PHYH ENTREZGENE
PANTHER PHYTANOYL-COA ALPHA-HYDROXYLASE UniProtKB/TrEMBL
  PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL UniProtKB/TrEMBL
Pfam PhyH UniProtKB/TrEMBL
Superfamily-SCOP Clavaminate synthase-like UniProtKB/TrEMBL
UniProt A0A2R9CCR1_PANPA UniProtKB/TrEMBL
  A0A2R9CKW2_PANPA UniProtKB/TrEMBL
  D7SD72_PANPA UniProtKB/TrEMBL
  D7SD73 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 PHYH  phytanoyl-CoA 2-hydroxylase  LOC100981160  uncharacterized LOC100981160  Data merged from RGD:11928608 737654 PROVISIONAL