THNSL2 (threonine synthase like 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: THNSL2 (threonine synthase like 2) Pan paniscus
Analyze
Symbol: THNSL2
Name: threonine synthase like 2
RGD ID: 12032717
Description: ENCODES a protein that exhibits lyase activity (inferred); pyridoxal phosphate binding (inferred); serine binding (inferred); INVOLVED IN threonine biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: threonine synthase-like 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,116,409 - 39,132,720 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,119,175 - 39,135,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,303,022 - 87,319,494 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,212,380 - 89,228,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,212,442 - 89,228,446 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
THNSL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,116,409 - 39,132,720 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,119,175 - 39,135,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,303,022 - 87,319,494 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,212,380 - 89,228,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,212,442 - 89,228,446 (+)Ensemblpanpan1.1panPan2
THNSL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38288,170,346 - 88,186,627 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl288,170,295 - 88,186,636 (+)EnsemblGRCh38hg38GRCh38
GRCh37288,469,865 - 88,486,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36288,250,950 - 88,267,261 (+)NCBINCBI36Build 36hg18NCBI36
Celera288,299,987 - 88,316,198 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef287,392,048 - 87,408,933 (+)NCBIHuRef
CHM1_1288,399,093 - 88,415,447 (+)NCBICHM1_1
T2T-CHM13v2.0288,181,454 - 88,198,653 (+)NCBIT2T-CHM13v2.0
Thnsl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,105,150 - 71,121,364 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,105,150 - 71,121,423 (-)EnsemblGRCm39 Ensembl
GRCm38671,128,166 - 71,144,380 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,128,166 - 71,144,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv37671,078,392 - 71,094,370 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,057,977 - 71,073,955 (-)NCBIMGSCv36mm8
Celera673,207,460 - 73,223,442 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.14NCBI
Thnsl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84104,671,305 - 104,691,084 (-)NCBIGRCr8
mRatBN7.24103,112,974 - 103,132,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,112,963 - 103,132,017 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4108,503,548 - 108,522,443 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,278,636 - 104,297,531 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04102,882,869 - 102,901,912 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,976,559 - 98,997,187 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,976,550 - 98,995,590 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,753,102 - 163,773,190 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,329,517 - 104,348,465 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14104,573,999 - 104,592,946 (-)NCBI
Celera492,288,587 - 92,307,161 (-)NCBICelera
Cytogenetic Map4q32NCBI
Thnsl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955424526,602 - 543,603 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955424526,967 - 543,603 (-)NCBIChiLan1.0ChiLan1.0
THNSL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,196,605 - 38,212,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1738,191,494 - 38,212,809 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1737,881,890 - 37,898,136 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01738,929,611 - 38,945,863 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1738,929,613 - 38,945,961 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,095,938 - 38,111,839 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,132,346 - 38,148,608 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,480,076 - 38,496,366 (-)NCBIUU_Cfam_GSD_1.0
Thnsl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629280,158,694 - 80,173,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936712681,133 - 699,792 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936712684,711 - 699,714 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THNSL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl357,799,026 - 57,823,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1357,800,976 - 57,821,296 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,654,264 - 60,669,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THNSL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11418,603,376 - 18,619,711 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1418,600,437 - 18,619,762 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660801,156,644 - 1,172,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thnsl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474916,213,785 - 16,226,700 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474916,198,423 - 16,229,952 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058818   ⟹   ENSPPAP00000035929
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,212,442 - 89,228,446 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000058825   ⟹   ENSPPAP00000035936
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,215,312 - 89,227,789 (+)Ensembl
RefSeq Acc Id: XM_003805853   ⟹   XP_003805901
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,478 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,238 (-)NCBI
Mhudiblu_PPA_v02A87,303,267 - 87,319,494 (+)NCBI
PanPan1.12A89,212,401 - 89,228,452 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008975906   ⟹   XP_008974154
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,720 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,471 (-)NCBI
Mhudiblu_PPA_v02A87,303,022 - 87,319,494 (+)NCBI
PanPan1.12A89,212,380 - 89,228,452 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034953512   ⟹   XP_034809403
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,478 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,238 (-)NCBI
Mhudiblu_PPA_v02A87,303,294 - 87,319,494 (+)NCBI
RefSeq Acc Id: XM_055107703   ⟹   XP_054963678
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,478 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,238 (-)NCBI
RefSeq Acc Id: XM_055107704   ⟹   XP_054963679
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,478 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,238 (-)NCBI
RefSeq Acc Id: XM_055107705   ⟹   XP_054963680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,131 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,188 (-)NCBI
RefSeq Acc Id: XM_057301275   ⟹   XP_057157258
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,460 (-)NCBI
NHGRI_mPanPan12A39,119,175 - 39,135,220 (-)NCBI
RefSeq Acc Id: XM_063594581   ⟹   XP_063450651
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,452 (-)NCBI
RefSeq Acc Id: XM_063594582   ⟹   XP_063450652
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,116,409 - 39,132,131 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008974154   ⟸   XM_008975906
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_003805901   ⟸   XM_003805853
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C1Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034809403   ⟸   XM_034953512
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C1Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000035929   ⟸   ENSPPAT00000058818
RefSeq Acc Id: ENSPPAP00000035936   ⟸   ENSPPAT00000058825
RefSeq Acc Id: XP_054963678   ⟸   XM_055107703
- Peptide Label: isoform X3
- UniProtKB: A0A2R9C1Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054963679   ⟸   XM_055107704
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054963680   ⟸   XM_055107705
- Peptide Label: isoform X5
RefSeq Acc Id: XP_057157258   ⟸   XM_057301275
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063450651   ⟸   XM_063594581
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063450652   ⟸   XM_063594582
- Peptide Label: isoform X2
Protein Domains
Threonine synthase N-terminal   Tryptophan synthase beta chain-like PALP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040746 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058818.1 UniProtKB/TrEMBL
  ENSPPAT00000058825.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1100 UniProtKB/TrEMBL
  3.90.1380.10 UniProtKB/TrEMBL
InterPro PLP-dep UniProtKB/TrEMBL
  Thr_synth_N UniProtKB/TrEMBL
  Thr_synth_N_sf UniProtKB/TrEMBL
  Thr_synthase-like UniProtKB/TrEMBL
  Trypto_synt_PLP_dependent UniProtKB/TrEMBL
KEGG Report pps:100982566 UniProtKB/TrEMBL
NCBI Gene THNSL2 ENTREZGENE
PANTHER THREONINE SYNTHASE FAMILY MEMBER UniProtKB/TrEMBL
  THREONINE SYNTHASE-LIKE 2 UniProtKB/TrEMBL
Pfam PALP UniProtKB/TrEMBL
  Thr_synth_N UniProtKB/TrEMBL
Superfamily-SCOP SSF53686 UniProtKB/TrEMBL
UniProt A0A2R9C1Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C4Y5_PANPA UniProtKB/TrEMBL