KHK (ketohexokinase) - Rat Genome Database

Name: KHK
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: KHK (ketohexokinase) Pan paniscus

Analyze

Symbol:

KHK

Name:

ketohexokinase

RGD ID:

12029311

Description:

ENCODES a protein that exhibits ketohexokinase activity (ortholog); INVOLVED IN fructose catabolic process (ortholog); fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate (ortholog); fructose metabolic process (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); essential fructosuria (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KHK (ketohexokinase)	NCBI	Ortholog
Mus musculus (house mouse):	Khk (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Khk (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Khk (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KHK (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Khk (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KHK (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KHK (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Khk (ketohexokinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	99,415,724 - 99,428,805 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	99,419,692 - 99,432,773 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	27,085,758 - 27,099,768 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	27,174,896 - 27,189,308 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	27,174,896 - 27,189,308 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

carbohydrate metabolic disorder (ISO)

essential fructosuria (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

hereditary fructose intolerance syndrome (ISO)

Tatton-Brown-Rahman syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate phosphorylation (IEA)

fructose catabolic process (ISO)

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate (ISO)

fructose metabolic process (IEA,ISO)

phosphate-containing compound metabolic process (IEA)

regulation of glycogen metabolic process (ISO)

response to fructose (ISO)

response to glucose (ISO)

response to insulin (ISO)

response to sucrose (ISO)

response to zinc ion (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (ISO)

nucleus (ISO)

Molecular Function

ketohexokinase activity (IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

fructose and mannose metabolic pathway (ISO)

fructosuria pathway (ISO)

hereditary fructose intolerance syndrome pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

KHK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	99,415,724 - 99,428,805 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	99,419,692 - 99,432,773 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	27,085,758 - 27,099,768 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	27,174,896 - 27,189,308 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	27,174,896 - 27,189,308 (+)	Ensembl	panpan1.1		panPan2

KHK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	27,086,772 - 27,100,762 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	27,086,772 - 27,100,762 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	27,309,640 - 27,323,630 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	27,163,115 - 27,177,123 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	27,221,770 - 27,235,252	NCBI
Celera	2	27,155,955 - 27,169,965 (+)	NCBI		Celera
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	27,051,765 - 27,065,924 (+)	NCBI		HuRef
CHM1_1	2	27,239,525 - 27,253,535 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	27,128,445 - 27,142,438 (+)	NCBI		T2T-CHM13v2.0

Khk
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	31,078,780 - 31,088,592 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	31,078,775 - 31,088,592 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	30,921,436 - 30,931,248 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	30,921,431 - 30,931,248 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	31,224,268 - 31,233,619 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	31,198,476 - 31,207,827 (+)	NCBI		MGSCv36	mm8
Celera	5	28,401,689 - 28,411,041 (+)	NCBI		Celera
Cytogenetic Map	5	B1	NCBI
cM Map	5	16.9	NCBI

Khk
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	31,165,246 - 31,175,779 (-)	NCBI		GRCr8
mRatBN7.2	6	25,445,298 - 25,455,834 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,445,300 - 25,455,717 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	25,745,610 - 25,755,833 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	26,061,474 - 26,071,697 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	25,540,659 - 25,550,901 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	26,810,577 - 26,821,013 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	26,810,579 - 26,820,959 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	36,626,192 - 36,636,617 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	25,428,263 - 25,438,497 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	25,431,217 - 25,441,313 (-)	NCBI
Celera	6	24,935,944 - 24,946,180 (-)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

Khk
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	9,058,095 - 9,071,091 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	9,058,095 - 9,071,091 (+)	NCBI	ChiLan1.0	ChiLan1.0

KHK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	21,079,907 - 21,092,510 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	21,079,907 - 21,092,510 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	20,971,570 - 20,984,321 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	21,399,371 - 21,413,177 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	21,399,398 - 21,413,176 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	21,086,630 - 21,099,927 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	21,097,714 - 21,111,029 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	21,144,127 - 21,157,862 (+)	NCBI		UU_Cfam_GSD_1.0

Khk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	65,384,457 - 65,395,298 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	5,441,165 - 5,455,176 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	5,444,284 - 5,455,100 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KHK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	112,021,108 - 112,031,620 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	112,021,163 - 112,031,615 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	119,019,718 - 119,030,168 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KHK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	80,518,049 - 80,531,643 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	80,514,825 - 80,531,653 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	31,608,128 - 31,621,763 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Khk
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	9,189,320 - 9,202,053 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	9,189,343 - 9,205,209 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003827079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003827080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008952447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008952448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008952449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008952450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055108136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000056598 ⟹ ENSPPAP00000033721

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	27,174,896 - 27,189,308 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000056604 ⟹ ENSPPAP00000033727

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	27,174,897 - 27,189,308 (+)	Ensembl

RefSeq Acc Id:

XM_003827079 ⟹ XP_003827127

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	99,415,724 - 99,428,804 (-)	NCBI
NHGRI_mPanPan1	2A	99,419,692 - 99,432,773 (-)	NCBI
Mhudiblu_PPA_v0	2A	27,085,758 - 27,099,768 (+)	NCBI
PanPan1.1	2A	27,174,897 - 27,189,308 (+)	NCBI

Sequence:

show sequence

GGGCGGGGCCGCCTCGACCGCGGGCTTCAGGCAGGGCTGCAGATGCGAGGCCCAGCTGTACCTC
GCGGGTCCAGGGTCGGGAGTCGGAGACGCAGGTGCAGGAGAGGGCGGGGCAAGTAGCGCATTTT
CTCTTTGCATTCTCGAGATCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCAT
CTGACAAGCGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGGCAACC
TGCTACGGAAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCAGCTCGGGTCTTCG
GGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGCTGCAGGTGGCTCC
CTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAGCGGGGACACCATCCTCC
TGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCGGGCAGGAAGCTCTGGGAGCAG
CCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGATGGCAGCGCGGAGGCA
ACGCGTCCAACTCCTGCACCGTTCTCTCCCTGCTCGGAGCCCCCTGTGCCTTCATGGGCTCAAT
GGCTCCTGGCCATGTTGCTGATTTTGTCCTGGATGACCTCCGCCGCTATTCTGTGGACCTACGC
TACACAGTCTTTCAGACCACAGGCTCCGTCCCCATCGCCACGGTCATCATCAACGAGGCCAGTG
GTAGCCGCACCATCCTATACTATGACAGGAGCCTGCCAGATGTGTCTGCTACGGACTTTGAGAA
GGTTGATCTGACCCAGTTCAAGTGGATCCACATTGAGGGCCGGAACGCATCGGAGCAGGTGAAG
ATGCTGCAGCGGATAGACGCACACAACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTGTCCG
TGGAGGTGGAGAAGCCACGAGAGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGTTTGT
CAGCAAAGATGTGGCCAAGCACTTGGGGTTCCAGTCAGCAGAGGAAGCCTTGAGGGGCTTGTAT
GGTCGTGTGAGGAAAGGGGCTGTGCTTGTCTGTGCCTGGGCTGAGGAGGGTGCCGACGCCCTGG
GCCCTGATGGCAAATTGCTCCACTCGGATGCTTTCCCGCCACCCCGCGTGGTGGATACACTGGG
AGCTGGAGACACCTTCAATGCCTCTGTCATCTTCAGCCTCTCCCAGGGGAGGAGCATGCAGGAA
GCACTGAGATTCGGGTGCCAGGTGGCCGGCAAGAAGTGTGGCCTGCAGGGCTTTGATGGCATCG
TGTGAGAGCAGGTGCCGGCTCCCCACACACCATGGAGACTACCATTGCGGCTGCATCGCCTTCT
CCCCTCCATCCAGCCTGGCGTCCAGGTTGCCCTGTTCAGGGGACAGATGCAAGCTGTGGGGAGG
ACTCTGCCTGTGTCCTGTGTTCCCCACACGCCTCTCCCTGCAGAGCCTCAGAGCAAATAAATCT
TCCTCAGAGCCAGCTTCTCCTGGCAGCTTCTGTCCTCAATGTCTGAACTGCTCTGGCTGGGCAT
TCCTGAGGCTCTGACTCTTTGATCCTCCCTGTGGCCATTCCCCAAATTAACCTCTCCGCCCAGG
CCCAGAGGAGGGGCTGCCTGGGCTAGAGCAGCGAGAAGTGCCCTGGGCTTGCCACCAGCTCTGC
CCTGGCCGGGGAGGACACTCAGTGCCCCACACCCAGTGAACCTGCCAAAGAAGCCGTGAGAGCT
CTGCGGGGCCCTGCGTTGTGCAGACTCTATTCCCACAGCTCAGAAGCTGGGAGTCCACACCGCT
GAGCTGAACTGACAGGCGAGTGGGGGGCAGGGGTGCGCCTCCTCTGCCCTGCCCACCAGCCTGT
GATTTGATGGGGTCTTCGTTGTCCAGAAATACCTCCTCCCGCTGACTGCCCCAGAGCCTGAAAG
TCTCACCCTTGGAGCCCACCTTGGAATTAAGGGCGTGCCTCAGCCACAAATGTGACCCAGGATA
CAGAGTGTTGCTGTCCTCAGGGAGGTCCGATCTGGAACACATATTGGAATTGGGGCCAACTCCA
ATATAGGGTGGGTAAGGCCTTATAATGTAAAGAACATATAATGTAAAGGGCTTTAGAGTCAGAC
AGACCTGGATTCAAATCTGCCATTTAATTAGCTGCATATCACCTTAGGGTACAGCACTTAACGC
AATCTGCCTCAATTTCTTCATCTGTCAAATGGAACCAATTCTGCTTGGCTACAGAATTATTGTG
AGGATAAAATCATATATAAAATGCCCAGCATGATG

hide sequence

RefSeq Acc Id:

XM_008952448 ⟹ XP_008950696

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	99,416,601 - 99,428,805 (-)	NCBI
NHGRI_mPanPan1	2A	99,420,569 - 99,432,773 (-)	NCBI
Mhudiblu_PPA_v0	2A	27,085,758 - 27,097,259 (+)	NCBI
PanPan1.1	2A	27,174,897 - 27,186,655 (+)	NCBI

Sequence:

show sequence

GGGCGGGGCCGCCTCGACCGCGGGCTTCAGGCAGGGCTGCAGATGCGAGGCCCAGCTGTACCTC
GCGGGTCCAGGGTCGGGAGTCGGAGACGCAGGTGCAGGAGAGGGCGGGGCAAGTAGCGCATTTT
CTCTTTGCATTCTCGAGATCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCAT
CTGACAAGCGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGGCAACC
TGCTACGGAAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCAGCTCGGGTCTTCG
GGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGCTGCAGGTGGCTCC
CTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAGCGGGGACACCATCCTCC
TGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCGGGCAGGAAGCTCTGGGAGCAG
CCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGATGGCAGCGCGGAGGCA
ACGCGTCCAACTCCTGCACCGTTCTCTCCCTGCTCGGAGCCCCCTGTGCCTTCATGGGCTCAAT
GGCTCCTGGCCATGTTGCTGATTTTGTCCTGGATGACCTCCGCCGCTATTCTGTGGACCTACGC
TACACAGTCTTTCAGACCACAGGCTCCGTCCCCATCGCCACGGTCATCATCAACGAGGCCAGTG
GTAGCCGCACCATCCTATACTATGACAGGAGCCTGCCAGATGTGTCTGCTACGGACTTTGAGAA
GGTTGATCTGACCCAGTTCAAGTGGATCCACATTGAGGGCCGGAACGCATCGGAGCAGGTGAAG
ATGCTGCAGCGGATAGACGCACACAACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTGTCCG
TGGAGGTGGAGAAGCCACGAGAGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGGGTGC
CCCATTCAGCCTCTCTTTGCCACTTCCAGCTAATTTGGTTCTTAAAGGGAGCCAGAATCCTTTT
ATCCTGCCTACCACAATTGGAATAGTGGTTCCTGGTTTGGTGGTGTTTGAAGATGGGGGATGGG
GGTTAAAGCAAAGAAGTAGACCCCTAGCCTTGGGCTCCAGTGCAGGCCTCAGCAGTGAGCAAGG
AGTAGAATGTCTCCACCCCAGGTGGATGCATAGGTGTAAGAATGCCCAGAGGGCTTGGGTAGGG
CTTAAACAGCCACAGGGCAAGCCTGTGTGGAAGCATCTCCTCTCTGGGGCTCCCCAGTCTTTTC
CTCTGCAGAATGAGGGCACACAACTGTTCTCTGAGGTTTCTTCCAACTCAGGGGTGTCTGGCAG
GTTGTGGGGGCTGCTGGGGTGAGGGAAGGGTGGGAAG

hide sequence

RefSeq Acc Id:

XM_008952449 ⟹ XP_008950697

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	99,416,601 - 99,428,805 (-)	NCBI
NHGRI_mPanPan1	2A	99,420,569 - 99,432,773 (-)	NCBI
Mhudiblu_PPA_v0	2A	27,085,758 - 27,097,259 (+)	NCBI
PanPan1.1	2A	27,174,897 - 27,186,655 (+)	NCBI

Sequence:

show sequence

GGGCGGGGCCGCCTCGACCGCGGGCTTCAGGCAGGGCTGCAGATGCGAGGCCCAGCTGTACCTC
GCGGGTCCAGGGTCGGGAGTCGGAGACGCAGGTGCAGGAGAGGGCGGGGCAAGTAGCGCATTTT
CTCTTTGCATTCTCGAGATCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCAT
CTGACAAGCGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGGCAACC
TGCTACGGAAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCAGCTCGGGTCTTCG
GGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGCTGCAGGTGGCTCC
CTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAGCGGGGACACCATCCTCC
TGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCGGGCAGGAAGCTCTGGGAGCAG
CCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGATGGCAGCGCGGAGGCA
ACGCGTCCAACTCCTGCACCGTTCTCTCCCTGCTCGGAGCCCCCTGTGCCTTCATGGGCTCAAT
GGCTCCTGGCCATGTTGCTGAGAGCCTGCCAGATGTGTCTGCTACGGACTTTGAGAAGGTTGAT
CTGACCCAGTTCAAGTGGATCCACATTGAGGGCCGGAACGCATCGGAGCAGGTGAAGATGCTGC
AGCGGATAGACGCACACAACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTGTCCGTGGAGGT
GGAGAAGCCACGAGAGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGGGTGCCCCATTC
AGCCTCTCTTTGCCACTTCCAGCTAATTTGGTTCTTAAAGGGAGCCAGAATCCTTTTATCCTGC
CTACCACAATTGGAATAGTGGTTCCTGGTTTGGTGGTGTTTGAAGATGGGGGATGGGGGTTAAA
GCAAAGAAGTAGACCCCTAGCCTTGGGCTCCAGTGCAGGCCTCAGCAGTGAGCAAGGAGTAGAA
TGTCTCCACCCCAGGTGGATGCATAGGTGTAAGAATGCCCAGAGGGCTTGGGTAGGGCTTAAAC
AGCCACAGGGCAAGCCTGTGTGGAAGCATCTCCTCTCTGGGGCTCCCCAGTCTTTTCCTCTGCA
GAATGAGGGCACACAACTGTTCTCTGAGGTTTCTTCCAACTCAGGGGTGTCTGGCAGGTTGTGG
GGGCTGCTGGGGTGAGGGAAGGGTGGGAAG

hide sequence

RefSeq Acc Id:

XM_008952450 ⟹ XP_008950698

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	99,416,601 - 99,428,805 (-)	NCBI
NHGRI_mPanPan1	2A	99,420,569 - 99,432,773 (-)	NCBI
Mhudiblu_PPA_v0	2A	27,085,758 - 27,097,259 (+)	NCBI
PanPan1.1	2A	27,174,897 - 27,186,811 (+)	NCBI

Sequence:

show sequence

GGGCGGGGCCGCCTCGACCGCGGGCTTCAGGCAGGGCTGCAGATGCGAGGCCCAGCTGTACCTC
GCGGGTCCAGGGTCGGGAGTCGGAGACGCAGGTGCAGGAGAGGGCGGGGCAAGTAGCGCATTTT
CTCTTTGCATTCTCGAGATCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCAT
CTGACAAGCGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGGCAACC
TGCTACGGAAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCAGCTCGGGTCTTCG
GGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGCTGCAGGTGGCTCC
CTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAGCGGGGACACCATCCTCC
TGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCGGGCAGGAAGCTCTGGGAGCAG
CCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGAGCCTGCCAGATGTGTCTGCTACGGACTTTG
AGAAGGTTGATCTGACCCAGTTCAAGTGGATCCACATTGAGGGCCGGAACGCATCGGAGCAGGT
GAAGATGCTGCAGCGGATAGACGCACACAACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTG
TCCGTGGAGGTGGAGAAGCCACGAGAGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGG
GTGCCCCATTCAGCCTCTCTTTGCCACTTCCAGCTAATTTGGTTCTTAAAGGGAGCCAGAATCC
TTTTATCCTGCCTACCACAATTGGAATAGTGGTTCCTGGTTTGGTGGTGTTTGAAGATGGGGGA
TGGGGGTTAAAGCAAAGAAGTAGACCCCTAGCCTTGGGCTCCAGTGCAGGCCTCAGCAGTGAGC
AAGGAGTAGAATGTCTCCACCCCAGGTGGATGCATAGGTGTAAGAATGCCCAGAGGGCTTGGGT
AGGGCTTAAACAGCCACAGGGCAAGCCTGTGTGGAAGCATCTCCTCTCTGGGGCTCCCCAGTCT
TTTCCTCTGCAGAATGAGGGCACACAACTGTTCTCTGAGGTTTCTTCCAACTCAGGGGTGTCTG
GCAGGTTGTGGGGGCTGCTGGGGTGAGGGAAGGGTGGGAAGGAGACTTGCATGAGTCTCTTTTT
GAAAAGGCTGGATGTAAATGGAATTTGGGAAGTAATCCCAGCATCATAGCAGAAGTTGGTTGGA
GACCATCCAGCCAAGGTCCTCAACCTTGTGACTTGTCCTCAACCTTGGCTGCATATTAAAAAAG
ATGAA

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RefSeq Acc Id:

XM_055108136 ⟹ XP_054964111

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	99,415,724 - 99,428,803 (-)	NCBI
NHGRI_mPanPan1	2A	99,419,692 - 99,432,773 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003827127	(Get FASTA)	NCBI Sequence Viewer
	XP_008950696	(Get FASTA)	NCBI Sequence Viewer
	XP_008950697	(Get FASTA)	NCBI Sequence Viewer
	XP_008950698	(Get FASTA)	NCBI Sequence Viewer
	XP_054964111	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000033721.1
	ENSPPAP00000033727
	ENSPPAP00000033727.1

RefSeq Acc Id:	XP_003827127 ⟸ XM_003827079
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BVM0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA PGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDVSATDFEKV DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVS KDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGA GDTFNASVIFSLSQGRSMQEALRFGCQVAGKKCGLQGFDGIV hide sequence

RefSeq Acc Id:

XP_008950698 ⟸ XM_008952450

- Peptide Label:

isoform X5

- Sequence:

show sequence

MEEKQILCVGLVVLDVISLVDKYPKEDSEIRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVK
MLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVGAPFSLSLPLPANLVLKGSQNPF
ILPTTIGIVVPGLVVFEDGGWGLKQRSRPLALGSSAGLSSEQGVECLHPRWMHRCKNAQRAWVG
LKQPQGKPVWKHLLSGAPQSFPLQNEGTQLFSEVSSNSGVSGRLWGLLG

hide sequence

RefSeq Acc Id:

XP_008950696 ⟸ XM_008952448

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA
PGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDVSATDFEKV
DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVGAP
FSLSLPLPANLVLKGSQNPFILPTTIGIVVPGLVVFEDGGWGLKQRSRPLALGSSAGLSSEQGV
ECLHPRWMHRCKNAQRAWVGLKQPQGKPVWKHLLSGAPQSFPLQNEGTQLFSEVSSNSGVSGRL
WGLLG

hide sequence

RefSeq Acc Id:

XP_008950697 ⟸ XM_008952449

- Peptide Label:

isoform X3

- Sequence:

show sequence

MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA
PGHVAESLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE
KPREELFQLFGYGDVVGAPFSLSLPLPANLVLKGSQNPFILPTTIGIVVPGLVVFEDGGWGLKQ
RSRPLALGSSAGLSSEQGVECLHPRWMHRCKNAQRAWVGLKQPQGKPVWKHLLSGAPQSFPLQN
EGTQLFSEVSSNSGVSGRLWGLLG

hide sequence

RefSeq Acc Id:

ENSPPAP00000033721 ⟸ ENSPPAT00000056598

RefSeq Acc Id:

ENSPPAP00000033727 ⟸ ENSPPAT00000056604

RefSeq Acc Id:	XP_054964111 ⟸ XM_055108136
- Peptide Label:	isoform X4

Protein Domains

Carbohydrate kinase PfkB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000039729	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000056598.1	UniProtKB/TrEMBL
	ENSPPAT00000056604.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1190.20	UniProtKB/TrEMBL
InterPro	KHK	UniProtKB/TrEMBL
	PfkB_dom	UniProtKB/TrEMBL
	Ribokinase-like	UniProtKB/TrEMBL
KEGG Report	pps:100986057	UniProtKB/TrEMBL
NCBI Gene	KHK	ENTREZGENE
PANTHER	PFKB-LIKE CARBOHYDRATE KINASE FAMILY PROTEIN	UniProtKB/TrEMBL
	PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN	UniProtKB/TrEMBL
Pfam	PfkB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53613	UniProtKB/TrEMBL
UniProt	A0A2R9BVM0	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BW88_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB