ADA (adenosine deaminase) - Rat Genome Database

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Gene: ADA (adenosine deaminase) Pan paniscus
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Symbol: ADA
Name: adenosine deaminase
RGD ID: 12028673
Description: ENCODES a protein that exhibits 2'-deoxyadenosine deaminase activity (ortholog); adenosine deaminase activity (ortholog); purine nucleoside binding (ortholog); INVOLVED IN adenosine catabolic process (ortholog); adenosine metabolic process (ortholog); aging (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH adenosine deaminase deficiency (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12042,044,613 - 42,076,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,044,613 - 42,076,868 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02040,950,238 - 40,982,481 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenosine catabolic process  (ISO)
adenosine metabolic process  (ISO)
aging  (ISO)
allantoin metabolic process  (ISO)
AMP catabolic process  (ISO)
AMP salvage  (ISO)
dAMP catabolic process  (ISO)
dATP catabolic process  (ISO)
deoxyadenosine catabolic process  (ISO)
embryonic digestive tract development  (ISO)
germinal center B cell differentiation  (ISO)
GMP salvage  (ISO)
histamine secretion  (ISO)
hypoxanthine biosynthetic process  (ISO)
in utero embryonic development  (ISO)
inosine biosynthetic process  (ISO)
liver development  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
negative regulation of adenosine receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of circadian sleep/wake cycle, non-REM sleep  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of leukocyte migration  (ISO)
negative regulation of mature B cell apoptotic process  (ISO)
negative regulation of mucus secretion  (ISO)
negative regulation of penile erection  (ISO)
negative regulation of thymocyte apoptotic process  (ISO)
Peyer's patch development  (ISO)
placenta development  (ISO)
positive regulation of alpha-beta T cell differentiation  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of germinal center formation  (ISO)
positive regulation of heart rate  (ISO)
positive regulation of smooth muscle contraction  (ISO)
positive regulation of T cell activation  (ISO)
positive regulation of T cell differentiation  (ISO)
positive regulation of T cell differentiation in thymus  (ISO)
positive regulation of T cell receptor signaling pathway  (ISO)
purine nucleotide salvage  (ISO)
regulation of cell-cell adhesion mediated by integrin  (ISO)
regulation of circadian sleep/wake cycle, sleep  (ISO)
regulation of T cell differentiation  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to inorganic substance  (ISO)
response to morphine  (ISO)
response to vitamin E  (ISO)
response to xenobiotic stimulus  (ISO)
T cell activation  (ISO)
trophectodermal cell differentiation  (ISO)
xanthine biosynthetic process  (ISO)

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
ADA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12042,044,613 - 42,076,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,044,613 - 42,076,868 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02040,950,238 - 40,982,481 (-)NCBIMhudiblu_PPA_v0panPan3
ADA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2044,619,522 - 44,652,233 (-)EnsemblGRCh38hg38GRCh38
GRCh382044,619,522 - 44,651,699 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372043,248,163 - 43,280,340 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362042,681,577 - 42,713,790 (-)NCBINCBI36hg18NCBI36
Build 342042,681,577 - 42,713,790NCBI
Celera2039,956,805 - 39,989,017 (-)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2039,989,704 - 40,021,872 (-)NCBIHuRef
CHM1_12043,151,279 - 43,183,492 (-)NCBICHM1_1
Ada
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,568,491 - 163,592,161 (-)NCBIGRCm39mm39
GRCm39 Ensembl2163,568,504 - 163,592,159 (-)Ensembl
GRCm382163,726,571 - 163,750,239 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2163,726,584 - 163,750,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv372163,552,320 - 163,575,913 (-)NCBIGRCm37mm9NCBIm37
MGSCv362163,418,025 - 163,441,618 (-)NCBImm8
Celera2169,670,309 - 169,693,933 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.44NCBI
Ada
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23152,398,745 - 152,422,854 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3152,398,747 - 152,447,088 (-)Ensembl
Rnor_6.03160,115,840 - 160,139,947 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3160,115,842 - 160,139,947 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03166,306,001 - 166,330,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,636,530 - 154,660,637 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13154,542,567 - 154,566,673 (-)NCBI
Celera3151,051,040 - 151,075,153 (-)NCBICelera
Cytogenetic Map3q42NCBI
Ada
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544512,696,096 - 12,717,488 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544512,696,096 - 12,717,488 (+)NCBIChiLan1.0ChiLan1.0
ADA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,083,786 - 32,119,810 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,083,931 - 32,111,160 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2431,725,150 - 31,756,275 (-)NCBI
ROS_Cfam_1.02432,790,716 - 32,821,895 (-)NCBI
UMICH_Zoey_3.12432,052,411 - 32,083,510 (-)NCBI
UNSW_CanFamBas_1.02432,167,117 - 32,198,181 (-)NCBI
UU_Cfam_GSD_1.02432,708,375 - 32,739,510 (-)NCBI
Ada
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640181,082,150 - 181,103,907 (-)NCBI
SpeTri2.0NW_0049365302,217,713 - 2,224,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,044,495 - 47,072,245 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,044,492 - 47,072,232 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21752,502,115 - 52,544,469 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1219,167,209 - 19,200,233 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605067,836,179 - 67,868,616 (+)NCBIVero_WHO_p1.0
Ada
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247909,809,550 - 9,829,199 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000027452   ⟹   ENSPPAP00000006326
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,044,613 - 42,076,868 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000027456   ⟹   ENSPPAP00000006328
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,044,615 - 42,076,868 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000027466   ⟹   ENSPPAP00000006331
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,045,214 - 42,062,663 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000027469   ⟹   ENSPPAP00000006333
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,046,230 - 42,062,663 (-)Ensembl
RefSeq Acc Id: XM_003825933   ⟹   XP_003825981
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12042,044,613 - 42,076,868 (-)NCBI
Mhudiblu_PPA_v02040,950,238 - 40,982,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951319   ⟹   XP_008949567
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.12042,044,613 - 42,076,868 (-)NCBI
Mhudiblu_PPA_v02040,950,238 - 40,982,475 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034947614   ⟹   XP_034803505
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02040,950,238 - 40,982,451 (-)NCBI
RefSeq Acc Id: XM_034947615   ⟹   XP_034803506
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02040,950,238 - 40,982,451 (-)NCBI
RefSeq Acc Id: XM_034947616   ⟹   XP_034803507
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02040,950,238 - 40,959,880 (-)NCBI
RefSeq Acc Id: XM_034947617   ⟹   XP_034803508
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02040,950,238 - 40,982,481 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_008949567   ⟸   XM_008951319
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_003825981   ⟸   XM_003825933
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034803508   ⟸   XM_034947617
- Peptide Label: isoform X6
RefSeq Acc Id: XP_034803506   ⟸   XM_034947615
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034803505   ⟸   XM_034947614
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034803507   ⟸   XM_034947616
- Peptide Label: isoform X5
RefSeq Acc Id: ENSPPAP00000006333   ⟸   ENSPPAT00000027469
RefSeq Acc Id: ENSPPAP00000006331   ⟸   ENSPPAT00000027466
RefSeq Acc Id: ENSPPAP00000006326   ⟸   ENSPPAT00000027452
RefSeq Acc Id: ENSPPAP00000006328   ⟸   ENSPPAT00000027456


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000024854 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000006326 ENTREZGENE
  ENSPPAP00000006328 ENTREZGENE
NCBI Gene ADA ENTREZGENE