ATP1B2 (ATPase Na+/K+ transporting subunit beta 2) - Rat Genome Database
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Gene: ATP1B2 (ATPase Na+/K+ transporting subunit beta 2) Pan paniscus
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Symbol: ATP1B2
Name: ATPase Na+/K+ transporting subunit beta 2
RGD ID: 12020951
Description: ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); P-type sodium:potassium-exchanging transporter activity (ortholog); INVOLVED IN cell-substrate adhesion (ortholog); cellular potassium ion homeostasis (ortholog); cellular sodium ion homeostasis (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH dyskeratosis congenita (ortholog); esophagus squamous cell carcinoma (ortholog); high grade glioma (ortholog); FOUND IN apical plasma membrane (ortholog); astrocyte end-foot (ortholog); astrocyte projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: sodium/potassium-transporting ATPase subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,669,997 - 7,675,730 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,669,626 - 7,673,834 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,681,831 - 7,688,710 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
ATP1B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,669,997 - 7,675,730 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,669,626 - 7,673,834 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,681,831 - 7,688,710 (+)NCBIMhudiblu_PPA_v0panPan3
ATP1B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,646,627 - 7,657,770 (+)EnsemblGRCh38hg38GRCh38
GRCh38177,646,627 - 7,657,770 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,549,945 - 7,561,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,494,979 - 7,501,814 (+)NCBINCBI36hg18NCBI36
Build 34177,494,978 - 7,501,814NCBI
Celera177,580,634 - 7,587,472 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,448,147 - 7,454,987 (+)NCBIHuRef
CHM1_1177,559,105 - 7,570,244 (+)NCBICHM1_1
Atp1b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,490,554 - 69,496,786 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,490,562 - 69,496,768 (-)Ensembl
GRCm381169,599,728 - 69,605,978 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,599,736 - 69,605,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,413,252 - 69,419,462 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,415,948 - 69,422,024 (-)NCBImm8
Celera1176,563,216 - 76,569,425 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.86NCBI
Atp1b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,318,698 - 54,324,933 (-)NCBI
Rnor_6.0 Ensembl1056,205,625 - 56,211,891 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01056,205,622 - 56,211,879 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,951,260 - 55,957,510 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,418,323 - 56,424,465 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,431,946 - 56,438,088 (-)NCBI
Celera1053,472,960 - 53,479,196 (-)NCBICelera
Cytogenetic Map10q24NCBI
Atp1b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,261,775 - 9,268,743 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,261,775 - 9,268,743 (-)NCBIChiLan1.0ChiLan1.0
ATP1B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl532,549,167 - 32,553,504 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1532,548,591 - 32,553,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Atp1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936595908,019 - 914,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,925,693 - 52,932,637 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,925,697 - 52,932,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,241,662 - 55,248,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP1B2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,030,016 - 7,035,620 (+)NCBI
ChlSab1.1 Ensembl167,030,055 - 7,037,754 (+)Ensembl
Atp1b2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478610,254,979 - 10,261,508 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034941461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000048035   ⟹   ENSPPAP00000025208
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl177,669,626 - 7,673,834 (+)Ensembl
RefSeq Acc Id: XM_034941461   ⟹   XP_034797352
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0177,681,831 - 7,688,710 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034797352 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034797352   ⟸   XM_034941461
RefSeq Acc Id: ENSPPAP00000025208   ⟸   ENSPPAT00000048035


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035739 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000025208 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048035 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1660 UniProtKB/TrEMBL
InterPro Na/K_ATPase_sub_beta UniProtKB/TrEMBL
  Na/K_ATPase_sub_beta_sf UniProtKB/TrEMBL
NCBI Gene ATP1B2 ENTREZGENE
PANTHER PTHR11523 UniProtKB/TrEMBL
Pfam Na_K-ATPase UniProtKB/TrEMBL
PROSITE ATPASE_NA_K_BETA_2 UniProtKB/TrEMBL
TIGRFAMs Na_K_ATPase_bet UniProtKB/TrEMBL
UniProt A0A2R9B6K3_PANPA UniProtKB/TrEMBL