LYRM4 (LYR motif containing 4) - Rat Genome Database

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Gene: LYRM4 (LYR motif containing 4) Pan paniscus
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Symbol: LYRM4
Name: LYR motif containing 4
RGD ID: 12019724
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN [2Fe-2S] cluster assembly (ortholog); [4Fe-4S] cluster assembly (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH combined oxidative phosphorylation deficiency 14 (ortholog); combined oxidative phosphorylation deficiency 19 (ortholog); hereditary spastic paraplegia 77 (ortholog); FOUND IN mitochondrial [2Fe-2S] assembly complex (ortholog); nuclear body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC106634842; LYR motif-containing protein 4; uncharacterized LOC106634842
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2519,660,550 - 19,890,104 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1615,684,672 - 15,894,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v064,887,010 - 5,096,384 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.165,126,916 - 5,279,037 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl65,127,918 - 5,279,038 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LYRM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2519,660,550 - 19,890,104 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1615,684,672 - 15,894,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v064,887,010 - 5,096,384 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.165,126,916 - 5,279,037 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl65,127,918 - 5,279,038 (-)Ensemblpanpan1.1panPan2
LYRM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3865,031,753 - 5,260,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl65,103,629 - 5,260,950 (-)EnsemblGRCh38hg38GRCh38
GRCh3765,068,561 - 5,261,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3665,053,652 - 5,206,167 (-)NCBINCBI36Build 36hg18NCBI36
Build 3465,053,652 - 5,206,167NCBI
Celera66,335,563 - 6,487,960 (-)NCBICelera
Cytogenetic Map6p25.1NCBI
HuRef64,983,042 - 5,135,587 (-)NCBIHuRef
CHM1_165,110,792 - 5,263,814 (-)NCBICHM1_1
T2T-CHM13v2.064,900,453 - 5,130,157 (-)NCBIT2T-CHM13v2.0
Lyrm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391336,162,778 - 36,301,543 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1336,162,378 - 36,301,509 (-)EnsemblGRCm39 Ensembl
GRCm381335,978,797 - 36,117,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1335,978,395 - 36,117,526 (-)EnsemblGRCm38mm10GRCm38
MGSCv371336,070,666 - 36,209,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361335,986,262 - 36,124,795 (-)NCBIMGSCv36mm8
Celera1337,094,464 - 37,232,801 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.44NCBI
Lyrm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81728,951,912 - 29,067,300 (+)NCBIGRCr8
mRatBN7.21728,746,457 - 28,861,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1728,746,469 - 28,861,750 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1728,606,677 - 28,722,099 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01730,210,222 - 30,325,648 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01728,582,619 - 28,697,699 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01729,439,042 - 29,552,773 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1729,438,980 - 29,552,790 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01731,335,552 - 31,449,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1728,351,102 - 28,464,094 (+)NCBICelera
Cytogenetic Map17p12NCBI
Lyrm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554658,346,012 - 8,470,251 (+)NCBIChiLan1.0ChiLan1.0
LYRM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,229,851 - 5,373,965 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,235,415 - 5,394,097 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,299,018 - 5,458,444 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1355,165,491 - 5,324,206 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,190,998 - 5,349,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0356,523,175 - 6,682,769 (-)NCBIUU_Cfam_GSD_1.0
Lyrm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494618,936,119 - 19,081,120 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365347,205,614 - 7,350,525 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365347,205,538 - 7,350,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYRM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl73,070,470 - 3,192,922 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.173,034,846 - 3,193,123 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.273,095,387 - 3,261,184 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LYRM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11766,921,386 - 67,077,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1766,921,596 - 67,076,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660445,050,918 - 5,208,300 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lyrm4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475620,017,066 - 20,152,201 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475620,016,773 - 20,152,201 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003806715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014345209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024929038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034961394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034961395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034961396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034961397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055113158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055113159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063605132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063605133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000034080   ⟹   ENSPPAP00000011424
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl65,127,918 - 5,278,826 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034085   ⟹   ENSPPAP00000011429
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl65,155,230 - 5,278,826 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034088   ⟹   ENSPPAP00000011432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl65,160,663 - 5,279,037 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034091   ⟹   ENSPPAP00000011435
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl65,205,370 - 5,279,038 (-)Ensembl
RefSeq Acc Id: XM_003806715   ⟹   XP_003806763
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,735,079 - 19,889,644 (-)NCBI
NHGRI_mPanPan1615,739,683 - 15,893,467 (-)NCBI
Mhudiblu_PPA_v064,941,351 - 5,096,152 (-)NCBI
PanPan1.165,126,916 - 5,279,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014345209   ⟹   XP_014200695
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,816,924 - 19,889,601 (-)NCBI
NHGRI_mPanPan1615,848,940 - 15,893,467 (-)NCBI
Mhudiblu_PPA_v065,051,198 - 5,096,160 (-)NCBI
PanPan1.165,234,754 - 5,279,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034961394   ⟹   XP_034817285
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,845,644 - 19,890,104 (-)NCBI
NHGRI_mPanPan1615,849,671 - 15,894,094 (-)NCBI
Mhudiblu_PPA_v065,051,997 - 5,096,384 (-)NCBI
RefSeq Acc Id: XM_034961395   ⟹   XP_034817286
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,735,079 - 19,890,104 (-)NCBI
NHGRI_mPanPan1615,739,683 - 15,893,972 (-)NCBI
Mhudiblu_PPA_v064,941,351 - 5,096,226 (-)NCBI
RefSeq Acc Id: XM_034961397   ⟹   XP_034817288
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,736,016 - 19,889,644 (-)NCBI
NHGRI_mPanPan1615,739,683 - 15,893,467 (-)NCBI
Mhudiblu_PPA_v064,942,289 - 5,096,160 (-)NCBI
RefSeq Acc Id: XM_055113158   ⟹   XP_054969133
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,758,247 - 19,763,703 (-)NCBI
NHGRI_mPanPan1615,763,755 - 15,767,687 (-)NCBI
RefSeq Acc Id: XM_055113159   ⟹   XP_054969134
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,696,209 - 19,889,644 (-)NCBI
NHGRI_mPanPan1615,700,571 - 15,893,467 (-)NCBI
RefSeq Acc Id: XM_063605132   ⟹   XP_063461202
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,692,162 - 19,889,601 (-)NCBI
RefSeq Acc Id: XM_063605133   ⟹   XP_063461203
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,758,247 - 19,889,601 (-)NCBI
RefSeq Acc Id: XR_010112373
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,674,963 - 19,889,601 (-)NCBI
RefSeq Acc Id: XR_010112374
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,673,196 - 19,889,601 (-)NCBI
RefSeq Acc Id: XR_010112375
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,660,550 - 19,889,601 (-)NCBI
RefSeq Acc Id: XR_010112376
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2519,660,550 - 19,889,601 (-)NCBI
RefSeq Acc Id: XP_003806763   ⟸   XM_003806715
- Peptide Label: isoform X5
- UniProtKB: A0A2R9A3H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014200695   ⟸   XM_014345209
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_034817286   ⟸   XM_034961395
- Peptide Label: isoform X7
RefSeq Acc Id: XP_034817288   ⟸   XM_034961397
- Peptide Label: isoform X8
- UniProtKB: A0A2R9A3H7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817285   ⟸   XM_034961394
- Peptide Label: isoform X4
Ensembl Acc Id: ENSPPAP00000011435   ⟸   ENSPPAT00000034091
Ensembl Acc Id: ENSPPAP00000011432   ⟸   ENSPPAT00000034088
Ensembl Acc Id: ENSPPAP00000011429   ⟸   ENSPPAT00000034085
Ensembl Acc Id: ENSPPAP00000011424   ⟸   ENSPPAT00000034080
RefSeq Acc Id: XP_054969134   ⟸   XM_055113159
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054969133   ⟸   XM_055113158
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063461202   ⟸   XM_063605132
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063461203   ⟸   XM_063605133
- Peptide Label: isoform X8
- UniProtKB: A0A2R9A3H7 (UniProtKB/TrEMBL)
Protein Domains
Complex 1 LYR protein


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028919 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034080.1 UniProtKB/TrEMBL
  ENSPPAT00000034085.1 UniProtKB/TrEMBL
  ENSPPAT00000034088.1 UniProtKB/TrEMBL
  ENSPPAT00000034091.1 UniProtKB/TrEMBL
InterPro Complex1_LYR UniProtKB/TrEMBL
  Complex1_LYR_LYRM4 UniProtKB/TrEMBL
  ISC_assembly_LYR UniProtKB/TrEMBL
KEGG Report pps:100978722 UniProtKB/TrEMBL
NCBI Gene LYRM4 ENTREZGENE
PANTHER LYR MOTIF-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  PROTEIN C6ORF149 UniProtKB/TrEMBL
Pfam Complex1_LYR UniProtKB/TrEMBL
UniProt A0A2R9A2C0_PANPA UniProtKB/TrEMBL
  A0A2R9A3H3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A3H7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A6W7_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 LYRM4  LYR motif containing 4  LOC106634842  uncharacterized LOC106634842  Data merged from RGD:11786253 737654 PROVISIONAL