PLA2G5 (phospholipase A2 group V) - Rat Genome Database

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Gene: PLA2G5 (phospholipase A2 group V) Pan paniscus
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Symbol: PLA2G5
Name: phospholipase A2 group V
RGD ID: 12014144
Description: ENCODES a protein that exhibits calcium-dependent phospholipase A2 activity (ortholog); heparin binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN arachidonate secretion (ortholog); leukotriene biosynthetic process (ortholog); low-density lipoprotein particle remodeling (ortholog); ASSOCIATED WITH 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ortholog); chromosome 1p36 deletion syndrome (ortholog); congenital disorder of glycosylation Ir (ortholog); FOUND IN cell surface (ortholog); early phagosome (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium-dependent phospholipase A2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,027,174 - 207,048,964 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,144,002 - 206,165,768 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,983,104 - 19,046,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,026,361 - 20,089,840 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,068,110 - 20,089,840 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLA2G5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,027,174 - 207,048,964 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,144,002 - 206,165,768 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,983,104 - 19,046,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,026,361 - 20,089,840 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,068,110 - 20,089,840 (+)Ensemblpanpan1.1panPan2
PLA2G5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38120,028,408 - 20,091,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl120,028,179 - 20,091,911 (+)EnsemblGRCh38hg38GRCh38
GRCh37120,396,687 - 20,418,404 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,269,288 - 20,290,981 (+)NCBINCBI36Build 36hg18NCBI36
Build 34120,142,143 - 20,162,959NCBI
Celera118,719,822 - 18,741,514 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef118,642,531 - 18,664,224 (+)NCBIHuRef
CHM1_1120,506,410 - 20,528,103 (+)NCBICHM1_1
T2T-CHM13v2.0119,852,033 - 19,915,547 (+)NCBIT2T-CHM13v2.0
Pla2g5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,526,558 - 138,590,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,526,555 - 138,590,793 (-)EnsemblGRCm39 Ensembl
GRCm384138,799,247 - 138,863,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,799,244 - 138,863,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,355,162 - 138,419,384 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,071,333 - 138,091,286 (-)NCBIMGSCv36mm8
Celera4140,584,350 - 140,649,745 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
Pla2g5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,324,628 - 156,393,065 (-)NCBIGRCr8
mRatBN7.25151,041,339 - 151,109,433 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,041,340 - 151,062,658 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,738,735 - 153,760,037 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,513,041 - 155,534,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,495,070 - 155,516,077 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,247,601 - 157,268,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,247,781 - 157,268,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,988,968 - 161,030,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,619,703 - 157,640,971 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,629,741 - 157,651,010 (-)NCBI
Celera5149,429,045 - 149,450,195 (-)NCBICelera
Cytogenetic Map5q36NCBI
Pla2g5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452710,271 - 723,142 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955452662,281 - 721,507 (+)NCBIChiLan1.0ChiLan1.0
PLA2G5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,762,851 - 78,781,642 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,762,852 - 78,781,983 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,276,435 - 75,295,216 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,329,011 - 79,347,745 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,329,015 - 79,347,767 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,148,347 - 76,167,055 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,154,883 - 77,173,638 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,225,847 - 78,234,080 (-)NCBIUU_Cfam_GSD_1.0
Pla2g5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,307,140 - 40,326,035 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364746,131,884 - 6,150,819 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364746,131,915 - 6,150,810 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,302,062 - 78,376,220 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,365,697 - 78,376,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2672,541,431 - 72,565,649 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,465,341 - 112,487,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,464,033 - 112,487,089 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,696,670 - 3,719,131 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla2g5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247645,196,215 - 5,207,232 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247645,196,215 - 5,207,138 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000018660   ⟹   ENSPPAP00000004022
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl120,068,110 - 20,089,840 (+)Ensembl
RefSeq Acc Id: XM_003814411   ⟹   XP_003814459
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21207,027,174 - 207,048,802 (-)NCBI
NHGRI_mPanPan11206,144,005 - 206,165,768 (-)NCBI
Mhudiblu_PPA_v0119,025,082 - 19,046,124 (+)NCBI
PanPan1.1120,068,110 - 20,089,840 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034957061   ⟹   XP_034812952
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21207,027,174 - 207,048,959 (-)NCBI
NHGRI_mPanPan11206,144,002 - 206,165,768 (-)NCBI
Mhudiblu_PPA_v0119,025,082 - 19,046,834 (+)NCBI
RefSeq Acc Id: XM_055097315   ⟹   XP_054953290
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21207,029,301 - 207,048,964 (-)NCBI
NHGRI_mPanPan11206,146,120 - 206,165,768 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003814459 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812952 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953290 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004022
  ENSPPAP00000004022.1
RefSeq Acc Id: XP_003814459   ⟸   XM_003814411
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZJJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034812952   ⟸   XM_034957061
- Peptide Label: isoform X1
Ensembl Acc Id: ENSPPAP00000004022   ⟸   ENSPPAT00000018660
RefSeq Acc Id: XP_054953290   ⟸   XM_055097315
- Peptide Label: isoform X3
Protein Domains
Phospholipase A2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000017051 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000018660.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.90.10 UniProtKB/TrEMBL
InterPro PLipase_A2 UniProtKB/TrEMBL
  PLipase_A2_Asp_AS UniProtKB/TrEMBL
  PLipase_A2_dom UniProtKB/TrEMBL
  PLipase_A2_dom_sf UniProtKB/TrEMBL
  PLipase_A2_His_AS UniProtKB/TrEMBL
KEGG Report pps:100975526 UniProtKB/TrEMBL
NCBI Gene PLA2G5 ENTREZGENE
PANTHER PHOSPHOLIPASE A2 GROUP V UniProtKB/TrEMBL
  PTHR11716 UniProtKB/TrEMBL
Pfam Phospholip_A2_1 UniProtKB/TrEMBL
PRINTS PHPHLIPASEA2 UniProtKB/TrEMBL
PROSITE PA2_ASP UniProtKB/TrEMBL
  PA2_HIS UniProtKB/TrEMBL
SMART PA2c UniProtKB/TrEMBL
Superfamily-SCOP SSF48619 UniProtKB/TrEMBL
UniProt A0A2R8ZJJ9 ENTREZGENE, UniProtKB/TrEMBL