DHX30 (DExH-box helicase 30) - Rat Genome Database

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Gene: DHX30 (DExH-box helicase 30) Pan paniscus
Analyze
Symbol: DHX30
Name: DExH-box helicase 30
RGD ID: 12013353
Description: ENCODES a protein that exhibits ATP binding (inferred); chromatin binding (inferred); double-stranded RNA binding (inferred); INVOLVED IN central nervous system development (inferred); mitochondrial large ribosomal subunit assembly (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial nucleoid (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DHX30; DEAH (Asp-Glu-Ala-His) box polypeptide 30; DEAH-box helicase 30; LOC100982992; LOC106634571; putative ATP-dependent RNA helicase DHX30; uncharacterized LOC100982992
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,775,971 - 47,823,434 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,715,275 - 47,762,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,833,785 - 48,858,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,819,125 - 48,857,964 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DHX30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,775,971 - 47,823,434 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,715,275 - 47,762,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,833,785 - 48,858,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,819,125 - 48,857,964 (+)Ensemblpanpan1.1panPan2
DHX30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,803,138 - 47,850,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,802,909 - 47,850,195 (+)EnsemblGRCh38hg38GRCh38
GRCh37347,844,628 - 47,891,683 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,819,655 - 47,866,687 (+)NCBINCBI36Build 36hg18NCBI36
Build 34347,819,654 - 47,866,686NCBI
Celera347,794,449 - 47,841,545 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,899,640 - 47,947,043 (+)NCBIHuRef
CHM1_1347,795,669 - 47,842,932 (+)NCBICHM1_1
T2T-CHM13v2.0347,830,461 - 47,877,524 (+)NCBIT2T-CHM13v2.0
Dhx30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,913,387 - 109,946,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,913,388 - 109,946,898 (-)EnsemblGRCm39 Ensembl
GRCm389110,084,319 - 110,117,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,084,320 - 110,117,830 (-)EnsemblGRCm38mm10GRCm38
MGSCv379109,986,824 - 110,018,086 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369109,929,496 - 109,960,758 (-)NCBIMGSCv36mm8
Celera9109,812,519 - 109,843,847 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.86NCBI
Dhx30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,943,186 - 118,975,319 (-)NCBIGRCr8
mRatBN7.28110,064,751 - 110,096,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,680,523 - 115,712,489 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,879,711 - 113,911,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,722,475 - 111,754,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,160,315 - 118,194,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,160,299 - 118,187,791 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,515,769 - 117,547,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,438,389 - 114,470,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,457,844 - 114,489,805 (-)NCBI
Celera8109,352,489 - 109,384,567 (-)NCBICelera
Cytogenetic Map8q32NCBI
Dhx30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,537,608 - 24,561,293 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,537,608 - 24,549,771 (-)NCBIChiLan1.0ChiLan1.0
DHX30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,102,064 - 41,131,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,102,080 - 41,129,429 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,019,046 - 41,048,443 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,585,579 - 41,614,984 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,585,582 - 41,614,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,827,709 - 40,857,125 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,229,130 - 41,258,515 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,508,803 - 41,538,213 (-)NCBIUU_Cfam_GSD_1.0
Dhx30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,870,062 - 201,905,658 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,421,094 - 1,455,356 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,419,165 - 1,454,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,617,376 - 30,632,497 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,602,008 - 30,632,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,878,421 - 33,908,846 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DHX30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1229,191,527 - 9,239,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl229,206,175 - 9,239,372 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,866,168 - 157,919,224 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx30
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,656,361 - 73,681,999 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473073,656,378 - 73,685,863 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045376   ⟹   ENSPPAP00000022565
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,819,125 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045382   ⟹   ENSPPAP00000022571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,828,125 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045456   ⟹   ENSPPAP00000022645
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,833,856 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045460   ⟹   ENSPPAP00000022649
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,833,856 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045467   ⟹   ENSPPAP00000022656
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,834,924 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045472   ⟹   ENSPPAP00000022661
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,834,976 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045485   ⟹   ENSPPAP00000022674
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,835,387 - 48,857,964 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045501   ⟹   ENSPPAP00000022689
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl348,835,767 - 48,857,964 (+)Ensembl
RefSeq Acc Id: XM_034956336   ⟹   XP_034812227
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,790,281 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,795,049 - 47,823,434 (+)NCBI
Mhudiblu_PPA_v0347,737,265 - 47,762,872 (+)NCBI
RefSeq Acc Id: XM_034956337   ⟹   XP_034812228
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,775,977 - 47,823,434 (+)NCBI
Mhudiblu_PPA_v0347,715,438 - 47,762,872 (+)NCBI
RefSeq Acc Id: XM_034956339   ⟹   XP_034812230
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,771,623 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,776,391 - 47,823,434 (+)NCBI
Mhudiblu_PPA_v0347,716,075 - 47,762,872 (+)NCBI
RefSeq Acc Id: XM_034956340   ⟹   XP_034812231
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,776,002 - 47,823,434 (+)NCBI
Mhudiblu_PPA_v0347,715,438 - 47,762,872 (+)NCBI
RefSeq Acc Id: XM_055109819   ⟹   XP_054965794
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,793,071 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,797,839 - 47,823,434 (+)NCBI
RefSeq Acc Id: XM_055109820   ⟹   XP_054965795
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,775,971 - 47,823,434 (+)NCBI
RefSeq Acc Id: XM_055109821   ⟹   XP_054965796
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,771,623 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,776,391 - 47,823,434 (+)NCBI
RefSeq Acc Id: XM_055109822   ⟹   XP_054965797
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,776,001 - 47,823,434 (+)NCBI
RefSeq Acc Id: XM_055109823   ⟹   XP_054965798
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,778,850 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,783,616 - 47,823,434 (+)NCBI
RefSeq Acc Id: XM_055109825   ⟹   XP_054965800
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2247,778,817 - 47,818,666 (+)NCBI
NHGRI_mPanPan1347,783,585 - 47,823,434 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034812228   ⟸   XM_034956337
- Peptide Label: isoform X6
- UniProtKB: A0A2R9AZA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034812231   ⟸   XM_034956340
- Peptide Label: isoform X7
- UniProtKB: A0A2R9AZD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034812230   ⟸   XM_034956339
- Peptide Label: isoform X6
- UniProtKB: A0A2R9AZA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034812227   ⟸   XM_034956336
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AZJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000022565   ⟸   ENSPPAT00000045376
RefSeq Acc Id: ENSPPAP00000022571   ⟸   ENSPPAT00000045382
RefSeq Acc Id: ENSPPAP00000022645   ⟸   ENSPPAT00000045456
RefSeq Acc Id: ENSPPAP00000022649   ⟸   ENSPPAT00000045460
RefSeq Acc Id: ENSPPAP00000022656   ⟸   ENSPPAT00000045467
RefSeq Acc Id: ENSPPAP00000022661   ⟸   ENSPPAT00000045472
RefSeq Acc Id: ENSPPAP00000022674   ⟸   ENSPPAT00000045485
RefSeq Acc Id: ENSPPAP00000022689   ⟸   ENSPPAT00000045501
RefSeq Acc Id: XP_054965795   ⟸   XM_055109820
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AZA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965797   ⟸   XM_055109822
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AZD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965796   ⟸   XM_055109821
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AZA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965800   ⟸   XM_055109825
- Peptide Label: isoform X8
- UniProtKB: A0A2R9AZD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965798   ⟸   XM_055109823
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AZD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965794   ⟸   XM_055109819
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AZJ2 (UniProtKB/TrEMBL)
Protein Domains
Helicase ATP-binding   Helicase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034330 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045376.1 UniProtKB/TrEMBL
  ENSPPAT00000045382.1 UniProtKB/TrEMBL
  ENSPPAT00000045456.1 UniProtKB/TrEMBL
  ENSPPAT00000045460.1 UniProtKB/TrEMBL
  ENSPPAT00000045467.1 UniProtKB/TrEMBL
  ENSPPAT00000045472.1 UniProtKB/TrEMBL
  ENSPPAT00000045485.1 UniProtKB/TrEMBL
  ENSPPAT00000045501.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1080 UniProtKB/TrEMBL
  3.30.160.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene DHX30 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DHX30 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  HA2_C UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  OB_NTP_bind UniProtKB/TrEMBL
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AZA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZA9_PANPA UniProtKB/TrEMBL
  A0A2R9AZD3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZF4_PANPA UniProtKB/TrEMBL
  A0A2R9AZJ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B565_PANPA UniProtKB/TrEMBL
  A0A2R9B5M0_PANPA UniProtKB/TrEMBL
  A0A2R9B5M8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 DHX30  DExH-box helicase 30  LOC100982992  uncharacterized LOC100982992  Data merged from RGD:12010929 737654 PROVISIONAL
2018-05-08 DHX30  DExH-box helicase 30  LOC106634571  putative ATP-dependent RNA helicase DHX30  Data merged from RGD:11901610 737654 PROVISIONAL