GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6) - Rat Genome Database

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Gene: GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6) Pan paniscus
Analyze
Symbol: GABRA6
Name: gamma-aminobutyric acid type A receptor subunit alpha6
RGD ID: 12012697
Description: ENCODES a protein that exhibits benzodiazepine receptor activity (ortholog); diazepam binding (ortholog); GABA-A receptor activity (ortholog); INVOLVED IN response to ethanol (ortholog); synaptic transmission, GABAergic (ortholog); ASSOCIATED WITH Binge Drinking (ortholog); childhood absence epilepsy (ortholog); Cushing Syndrome (ortholog); FOUND IN cerebellar Golgi cell to granule cell synapse (ortholog); dendrite (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gamma-aminobutyric acid receptor subunit alpha-6; gamma-aminobutyric acid type A receptor alpha6 subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24156,868,647 - 156,885,816 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15155,008,214 - 155,025,362 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05157,072,915 - 157,089,994 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15163,767,304 - 163,784,334 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5163,767,304 - 163,784,331 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GABRA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24156,868,647 - 156,885,816 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15155,008,214 - 155,025,362 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05157,072,915 - 157,089,994 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15163,767,304 - 163,784,334 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5163,767,304 - 163,784,331 (+)Ensemblpanpan1.1panPan2
GABRA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385161,685,721 - 161,702,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5161,547,063 - 161,702,593 (+)EnsemblGRCh38hg38GRCh38
GRCh375161,112,727 - 161,129,598 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365161,045,236 - 161,062,176 (+)NCBINCBI36Build 36hg18NCBI36
Build 345161,045,547 - 161,061,697NCBI
Celera5157,144,516 - 157,161,456 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5156,205,057 - 156,221,975 (+)NCBIHuRef
CHM1_15160,545,077 - 160,562,018 (+)NCBICHM1_1
T2T-CHM13v2.05162,214,591 - 162,231,464 (+)NCBIT2T-CHM13v2.0
Gabra6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391142,197,264 - 42,211,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1142,197,264 - 42,211,899 (-)EnsemblGRCm39 Ensembl
GRCm381142,306,437 - 42,321,072 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1142,306,437 - 42,321,072 (-)EnsemblGRCm38mm10GRCm38
MGSCv371142,119,939 - 42,134,553 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361142,149,861 - 42,164,431 (-)NCBIMGSCv36mm8
Celera1146,139,046 - 46,153,582 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1125.03NCBI
Gabra6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81027,311,965 - 27,327,337 (-)NCBIGRCr8
mRatBN7.21026,810,411 - 26,825,768 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1026,810,423 - 26,825,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1031,546,343 - 31,560,549 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01031,034,879 - 31,049,081 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01026,521,557 - 26,535,757 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01027,847,447 - 27,862,896 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1027,847,439 - 27,862,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01027,691,630 - 27,706,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41027,474,071 - 27,489,074 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11027,475,119 - 27,490,123 (-)NCBI
Celera1026,323,497 - 26,337,672 (-)NCBICelera
Cytogenetic Map10q21NCBI
Gabra6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540815,464,368 - 15,480,330 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540815,464,426 - 15,479,653 (+)NCBIChiLan1.0ChiLan1.0
GABRA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1449,208,691 - 49,225,754 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl449,208,605 - 49,226,212 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha449,099,501 - 49,116,828 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0449,639,863 - 49,657,617 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl449,640,367 - 49,657,815 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1449,446,978 - 49,464,698 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0449,579,983 - 49,597,659 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0450,103,326 - 50,121,062 (-)NCBIUU_Cfam_GSD_1.0
Gabra6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213103,533,076 - 103,548,851 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365151,980,824 - 1,998,053 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365151,982,415 - 1,997,740 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1661,855,468 - 61,872,279 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11661,855,698 - 61,872,503 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21667,083,554 - 67,100,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12364,020,770 - 64,038,419 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2364,021,842 - 64,039,563 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603413,515,669 - 13,532,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabra6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473327,910,641 - 27,926,376 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473327,910,692 - 27,926,104 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000026990   ⟹   ENSPPAP00000006156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5163,767,304 - 163,784,331 (+)Ensembl
RefSeq Acc Id: XM_003808015   ⟹   XP_003808063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24156,868,668 - 156,885,815 (+)NCBI
NHGRI_mPanPan15155,008,232 - 155,025,361 (+)NCBI
Mhudiblu_PPA_v05157,072,940 - 157,089,491 (+)NCBI
PanPan1.15163,767,304 - 163,783,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960108   ⟹   XP_008958356
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24156,868,647 - 156,885,816 (+)NCBI
NHGRI_mPanPan15155,008,214 - 155,025,362 (+)NCBI
Mhudiblu_PPA_v05157,072,915 - 157,089,994 (+)NCBI
PanPan1.15163,767,304 - 163,784,334 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003808063 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958356 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000006156
  ENSPPAP00000006156.1
Reference Protein Sequences
RefSeq Acc Id: XP_008958356   ⟸   XM_008960108
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003808063   ⟸   XM_003808015
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZQ75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000006156   ⟸   ENSPPAT00000026990
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000024473 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000026990.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/TrEMBL
  GABAAa_rcpt UniProtKB/TrEMBL
  GABBAa6_rcpt UniProtKB/TrEMBL
  Gabra-1-6_TM UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
KEGG Report pps:100976047 UniProtKB/TrEMBL
NCBI Gene GABRA6 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS GABAARALPHA UniProtKB/TrEMBL
  GABAARALPHA6 UniProtKB/TrEMBL
  GABAARECEPTR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A2R8ZQ75 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 GABRA6  gamma-aminobutyric acid type A receptor subunit alpha6  GABRA6  gamma-aminobutyric acid type A receptor alpha6 subunit  Symbol and/or name change 5135510 APPROVED