SLC39A8 (solute carrier family 39 member 8) - Rat Genome Database

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Gene: SLC39A8 (solute carrier family 39 member 8) Pan paniscus
Analyze
Symbol: SLC39A8
Name: solute carrier family 39 member 8
RGD ID: 12012090
Description: ENCODES a protein that exhibits metal ion transmembrane transporter activity (inferred); monoatomic cation:bicarbonate symporter activity (inferred); zinc ion transmembrane transporter activity (inferred); INVOLVED IN arginine metabolic process (ortholog); cadmium ion transmembrane transport (ortholog); cartilage homeostasis (ortholog); PARTICIPATES IN iron uptake pathway; ASSOCIATED WITH beta-mannosidosis (ortholog); congenital disorder of glycosylation type IIn (ortholog); Crohn's disease (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lysosomal membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metal cation symporter ZIP8; zinc transporter ZIP8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23100,339,570 - 100,430,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14100,626,388 - 100,716,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0494,675,458 - 94,770,380 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14105,339,488 - 105,433,813 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4105,339,488 - 105,433,568 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC39A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23100,339,570 - 100,430,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14100,626,388 - 100,716,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0494,675,458 - 94,770,380 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14105,339,488 - 105,433,813 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4105,339,488 - 105,433,568 (-)Ensemblpanpan1.1panPan2
SLC39A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384102,251,041 - 102,345,482 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4102,251,080 - 102,431,258 (-)EnsemblGRCh38hg38GRCh38
GRCh374103,172,198 - 103,266,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364103,401,844 - 103,485,371 (-)NCBINCBI36Build 36hg18NCBI36
Build 344103,539,998 - 103,623,526NCBI
Celera4100,470,678 - 100,565,146 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef498,909,550 - 99,003,934 (-)NCBIHuRef
CHM1_14103,148,714 - 103,243,025 (-)NCBICHM1_1
T2T-CHM13v2.04105,565,252 - 105,659,701 (-)NCBIT2T-CHM13v2.0
Slc39a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393135,522,644 - 135,594,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3135,531,040 - 135,594,333 (+)EnsemblGRCm39 Ensembl
GRCm383135,816,882 - 135,888,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3135,825,279 - 135,888,572 (+)EnsemblGRCm38mm10GRCm38
MGSCv373135,488,455 - 135,551,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363135,763,475 - 135,825,778 (+)NCBIMGSCv36mm8
Celera3142,245,991 - 142,312,950 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.04NCBI
Slc39a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82226,845,686 - 226,992,668 (+)NCBIGRCr8
mRatBN7.22224,171,787 - 224,319,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2224,256,654 - 224,319,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2231,982,580 - 232,044,754 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02229,882,319 - 229,944,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02224,746,913 - 224,809,087 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02241,028,851 - 241,092,584 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2241,029,693 - 241,092,582 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02259,584,747 - 259,648,098 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42233,340,397 - 233,403,461 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12233,327,136 - 233,390,197 (+)NCBI
Celera2216,458,405 - 216,522,357 (+)NCBICelera
Cytogenetic Map2q43NCBI
Slc39a8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554966,040,029 - 6,109,907 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554966,016,727 - 6,106,965 (+)NCBIChiLan1.0ChiLan1.0
SLC39A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13223,727,920 - 23,801,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3223,729,476 - 23,800,941 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3218,223,143 - 18,296,028 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03223,949,019 - 24,021,586 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3223,949,029 - 24,022,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13223,928,002 - 24,000,562 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03223,708,061 - 23,781,012 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03216,083,043 - 16,156,566 (+)NCBIUU_Cfam_GSD_1.0
Slc39a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530117,620,065 - 17,693,363 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936520962,756 - 1,037,274 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936520961,376 - 1,036,801 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC39A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8118,605,402 - 118,678,107 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18118,604,852 - 118,678,115 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28127,753,647 - 127,825,292 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC39A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1750,355,756 - 50,451,253 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl750,367,436 - 50,451,510 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603728,867,139 - 28,956,324 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc39a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248305,514,780 - 5,574,894 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248305,514,595 - 5,573,250 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000048703   ⟹   ENSPPAP00000025873
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4105,339,488 - 105,433,568 (-)Ensembl
RefSeq Acc Id: XM_055111663   ⟹   XP_054967638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23100,345,481 - 100,430,481 (-)NCBI
NHGRI_mPanPan14100,632,327 - 100,716,146 (-)NCBI
RefSeq Acc Id: XM_055111664   ⟹   XP_054967639
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23100,339,570 - 100,429,660 (-)NCBI
NHGRI_mPanPan14100,626,388 - 100,716,146 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054967638 (Get FASTA)   NCBI Sequence Viewer  
  XP_054967639 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025873.1
Ensembl Acc Id: ENSPPAP00000025873   ⟸   ENSPPAT00000048703
RefSeq Acc Id: XP_054967639   ⟸   XM_055111664
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B8F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054967638   ⟸   XM_055111663
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B8F3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036056 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048703.1 UniProtKB/TrEMBL
InterPro ZIP UniProtKB/TrEMBL
  ZIP_Transporter UniProtKB/TrEMBL
NCBI Gene SLC39A8 ENTREZGENE
PANTHER METAL CATION SYMPORTER ZIP8 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 39 UniProtKB/TrEMBL
Pfam Zip UniProtKB/TrEMBL
UniProt A0A2R9B8F3 ENTREZGENE, UniProtKB/TrEMBL