FXYD7 (FXYD domain containing ion transport regulator 7)

Gene: FXYD7 (FXYD domain containing ion transport regulator 7) Pan paniscus

Analyze

Symbol:

FXYD7

Name:

FXYD domain containing ion transport regulator 7

RGD ID:

12011426

Description:

ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN regulation of monoatomic ion transport (ortholog); ASSOCIATED WITH Brugada syndrome 5 (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

FXYD domain-containing ion transport regulator 7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	41,155,278 - 41,166,543 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	43,138,646 - 43,149,891 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	32,089,090 - 32,100,331 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	40,827,468 - 40,838,549 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	40,827,468 - 40,838,549 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brugada syndrome 5 (ISO)

dystonia (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 75 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoatomic ion transport (IEA)

regulation of monoatomic ion transport (IEA,ISO)

Cellular Component

membrane (IEA)

plasma membrane (ISO)

Molecular Function

ATPase binding (ISO)

ion channel regulator activity (IEA)

protein binding (ISO)

sodium channel regulator activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FXYD7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	41,155,278 - 41,166,543 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	43,138,646 - 43,149,891 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	32,089,090 - 32,100,331 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	40,827,468 - 40,838,549 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	40,827,468 - 40,838,549 (+)	Ensembl	panpan1.1		panPan2

FXYD7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	35,143,255 - 35,154,302 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	35,143,250 - 35,154,302 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	35,634,159 - 35,645,205 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	40,325,994 - 40,337,045 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	40,325,993 - 40,337,045	NCBI
Celera	19	32,347,590 - 32,358,642 (+)	NCBI		Celera
Cytogenetic Map	19	q13.12	NCBI
HuRef	19	32,142,138 - 32,153,582 (+)	NCBI		HuRef
CHM1_1	19	35,636,092 - 35,647,092 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	37,687,602 - 37,698,927 (+)	NCBI		T2T-CHM13v2.0

Fxyd7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	30,741,940 - 30,750,879 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	30,741,938 - 30,750,892 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	31,042,515 - 31,051,454 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	31,042,513 - 31,051,467 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	31,827,534 - 31,836,473 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	30,751,275 - 30,760,214 (-)	NCBI		MGSCv36	mm8
Celera	7	25,610,035 - 25,618,974 (-)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	19.29	NCBI

Fxyd7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	95,405,071 - 95,414,407 (-)	NCBI		GRCr8
mRatBN7.2	1	86,277,678 - 86,286,954 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	86,277,678 - 86,286,954 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	91,698,075 - 91,707,340 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	100,164,220 - 100,173,485 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	93,456,352 - 93,465,618 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	89,474,601 - 89,484,069 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	89,474,601 - 89,483,988 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	90,630,083 - 90,639,163 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	86,086,024 - 86,095,045 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	86,164,134 - 86,173,156 (-)	NCBI
Celera	1	80,646,722 - 80,655,737 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Fxyd7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	4,460,899 - 4,469,936 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	4,460,899 - 4,469,936 (+)	NCBI	ChiLan1.0	ChiLan1.0

FXYD7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	117,431,620 - 117,432,877 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	116,827,739 - 116,836,769 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	118,024,670 - 118,033,704 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	118,024,676 - 118,033,686 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	117,587,291 - 117,596,413 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	117,212,620 - 117,221,642 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	118,269,089 - 118,278,125 (-)	NCBI		UU_Cfam_GSD_1.0

FXYD7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	30,076,144 - 30,087,176 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	30,076,294 - 30,086,786 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	7,849,379 - 7,860,533 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fxyd7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	8,359,477 - 8,368,349 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	8,359,477 - 8,368,419 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003816157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008969211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034944686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000032739 ⟹ ENSPPAP00000010092

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	40,827,468 - 40,838,549 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000032743 ⟹ ENSPPAP00000010096

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	40,827,505 - 40,838,549 (+)	Ensembl

RefSeq Acc Id:

XM_003816157 ⟹ XP_003816205

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	41,155,477 - 41,166,543 (+)	NCBI
NHGRI_mPanPan1	19	43,138,813 - 43,149,891 (+)	NCBI
Mhudiblu_PPA_v0	19	32,089,282 - 32,100,331 (+)	NCBI
PanPan1.1	19	40,827,468 - 40,838,549 (+)	NCBI

Sequence:

show sequence

GGGTGGCCTGCACGGGGGCGGGCTCCCCGGGCCCCATTTGGCTGCAGGCCCCCCCACGCCAGGG
CTCCCCCCAGCTCCCCCCACATCGGTCCGTCCTGCTTCCAGCTGCTGCAGCGCGCCTTCGCCGC
CAAAGCATCCAGCAGCCCCCTGCTCCGGCCCAGCATGGCGACCCCGACCCAGACCCCCACAAAG
GCTCCTGAGGAACCTGACCCATTTTACTATGACTACAACACGGTGCAGACTGTGGGCATGACTC
TGGCAACCATCTTGTTCCTGCTGGGTATCCTCATCGTCATCAGCAAGAAGGTGAAGTGCAGGAA
GGCGGACTCCAGGTCTGAGAGCCCAACCTGCAAATCCTGTAAGTCTGAGCTTCCCTCTTCAGCC
CCTGGTGGCGGCGGCGTGTAACACCTTCCCGAAGAAACTCCGCTGCCGACCCTGCCTGAGCGCG
GGAGCCTGAGGACCGGGTGGAGGCGGTGGGGACCCAGCCGCGCGCCGGGAGCGCTCCCCGGAAT
GAGCCGCCCCACCCACCCCAAGGCTGGAGCCGCTGCACCCTGCTGTCCCTCCCCAGGCCTTGGC
AATGACGATCCCCCAAAGAGCCCGTCTGCACCCCAGACCCAGGGCCTTAGGCCTCCAGCTCCTG
GGATCCGGGAGTTCATCCCGGCCCAGCACCCCCAGCATCCCCGTGTATGGCCCCCCTGCACCTC
CTTGTCTCATCCCCGAAGATCCGTCCCCCTGGCCCCTCAGTGTCCATGTCTTGAGCTTAATAAA
TGTGCATTTGGTTTTTTCCCCTG

hide sequence

RefSeq Acc Id:

XM_008969211 ⟹ XP_008967459

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	41,155,448 - 41,166,543 (+)	NCBI
NHGRI_mPanPan1	19	43,138,777 - 43,149,891 (+)	NCBI
Mhudiblu_PPA_v0	19	32,089,282 - 32,100,330 (+)	NCBI
PanPan1.1	19	40,827,505 - 40,838,549 (+)	NCBI

Sequence:

show sequence

TTGGCTGCAGGCCCCCCCACGCCAGGGCTCCCCCCAGCTCCCCCCACATCGGTCCGTCCTGCTT
CCAGCTGCTGCAGCGCGCCTTCGCCGCCAAAGCATCCAGCAGCCCCCTGCTCCGGCCCAGCATG
GCGACCCCGACCCAGACCCCCACAAAGGCTCCTGAGGAACCTGACCCATTTTACTATGACTACA
ACACGGTGCAGACTGTGGGCATGACTCTGGCAACCATCTTGTTCCTGCTGGGTATCCTCATCGT
CATCAGCAAGAAGGTGAAGTGCAGGAAGGCGGACTCCAGCCCAACCTGCAAATCCTGTAAGTCT
GAGCTTCCCTCTTCAGCCCCTGGTGGCGGCGGCGTGTAACACCTTCCCGAAGAAACTCCGCTGC
CGACCCTGCCTGAGCGCGGGAGCCTGAGGACCGGGTGGAGGCGGTGGGGACCCAGCCGCGCGCC
GGGAGCGCTCCCCGGAATGAGCCGCCCCACCCACCCCAAGGCTGGAGCCGCTGCACCCTGCTGT
CCCTCCCCAGGCCTTGGCAATGACGATCCCCCAAAGAGCCCGTCTGCACCCCAGACCCAGGGCC
TTAGGCCTCCAGCTCCTGGGATCCGGGAGTTCATCCCGGCCCAGCACCCCCAGCATCCCCGTGT
ATGGCCCCCCTGCACCTCCTTGTCTCATCCCCGAAGATCCGTCCCCCTGGCCCCTCAGTGTCCA
TGTCTTGAGCTTAATAAATGTGCATTTGGTTTTTTCCCCTG

hide sequence

RefSeq Acc Id:

XM_034944686 ⟹ XP_034800577

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	41,155,278 - 41,166,543 (+)	NCBI
NHGRI_mPanPan1	19	43,138,646 - 43,149,891 (+)	NCBI
Mhudiblu_PPA_v0	19	32,089,090 - 32,100,330 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003816205	(Get FASTA)	NCBI Sequence Viewer
	XP_008967459	(Get FASTA)	NCBI Sequence Viewer
	XP_034800577	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000010092
	ENSPPAP00000010092.1
	ENSPPAP00000010096.1

RefSeq Acc Id:	XP_003816205 ⟸ XM_003816157
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZYP9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSRSESPTCK SCKSELPSSAPGGGGV hide sequence

RefSeq Acc Id:	XP_008967459 ⟸ XM_008969211
- Peptide Label:	isoform X2
- Sequence:	show sequence MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSSPTCKSCK SELPSSAPGGGGV hide sequence

RefSeq Acc Id:	XP_034800577 ⟸ XM_034944686
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZYP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSPPAP00000010096 ⟸ ENSPPAT00000032743

RefSeq Acc Id:

ENSPPAP00000010092 ⟸ ENSPPAT00000032739

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000028283	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000032739.1	UniProtKB/TrEMBL
	ENSPPAT00000032743.1	UniProtKB/TrEMBL
Gene3D-CATH	Single helix bin	UniProtKB/TrEMBL
InterPro	FXYD7	UniProtKB/TrEMBL
	FXYD_motif	UniProtKB/TrEMBL
	Ion-transport_regulator_FXYD	UniProtKB/TrEMBL
KEGG Report	pps:100971458	UniProtKB/TrEMBL
NCBI Gene	FXYD7	ENTREZGENE
PANTHER	FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 7	UniProtKB/TrEMBL
	SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA	UniProtKB/TrEMBL
Pfam	ATP1G1_PLM_MAT8	UniProtKB/TrEMBL
PROSITE	FXYD	UniProtKB/TrEMBL
UniProt	A0A2R8ZYN6_PANPA	UniProtKB/TrEMBL
	A0A2R8ZYP9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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