RDH5 (retinol dehydrogenase 5) - Rat Genome Database

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Gene: RDH5 (retinol dehydrogenase 5) Pan paniscus
Analyze
Symbol: RDH5
Name: retinol dehydrogenase 5
RGD ID: 12010355
Description: ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); androstan-3-alpha,17-beta-diol dehydrogenase activity (inferred); androsterone dehydrogenase activity (inferred); INVOLVED IN endosomal transport (inferred); retinoid metabolic process (inferred); steroid metabolic process (inferred); PARTICIPATES IN retinoid cycle metabolic pathway; ASSOCIATED WITH Congenital Abnormalities (ortholog); congenital stationary night blindness (ortholog); fundus albipunctatus (ortholog); FOUND IN cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 11-cis retinol dehydrogenase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,603,587 - 38,608,452 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,600,356 - 38,605,222 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01233,186,871 - 33,191,539 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,911,309 - 33,916,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,911,309 - 33,920,506 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RDH5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,603,587 - 38,608,452 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,600,356 - 38,605,222 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01233,186,871 - 33,191,539 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,911,309 - 33,916,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,911,309 - 33,920,506 (-)Ensemblpanpan1.1panPan2
RDH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,720,393 - 55,724,705 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,720,367 - 55,724,705 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,114,177 - 56,118,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,400,488 - 54,404,756 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,400,487 - 54,404,754NCBI
Celera1255,766,620 - 55,770,996 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,152,966 - 53,157,341 (+)NCBIHuRef
CHM1_11256,080,940 - 56,085,314 (+)NCBICHM1_1
T2T-CHM13v2.01255,687,027 - 55,691,339 (+)NCBIT2T-CHM13v2.0
Rdh5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,749,457 - 128,755,906 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,749,462 - 128,758,757 (-)EnsemblGRCm39 Ensembl
GRCm3810128,913,588 - 128,920,037 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,913,593 - 128,922,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,350,646 - 128,356,353 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,316,537 - 128,322,222 (-)NCBIMGSCv36mm8
Celera10131,306,272 - 131,311,979 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.19NCBI
Rdh5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,912,120 - 1,931,836 (-)NCBIGRCr8
mRatBN7.271,341,172 - 1,346,863 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,340,934 - 1,351,558 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx74,105,451 - 4,111,129 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,981,111 - 5,986,789 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.076,282,399 - 6,288,308 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.073,335,681 - 3,342,573 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,335,742 - 3,342,491 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,305,900 - 3,311,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,212,121 - 2,217,394 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.172,215,941 - 2,216,641 (-)NCBI
Celera71,211,351 - 1,216,834 (-)NCBICelera
Cytogenetic Map7q11NCBI
Rdh5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,352,012 - 3,365,080 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,356,324 - 3,361,701 (+)NCBIChiLan1.0ChiLan1.0
RDH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110120,386 - 125,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10120,057 - 125,197 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10182,788 - 187,948 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010127,659 - 132,829 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10124,738 - 132,464 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110105,355 - 110,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010348,472 - 353,628 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010472,362 - 477,524 (+)NCBIUU_Cfam_GSD_1.0
Rdh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,674,990 - 58,678,776 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646191,128 - 199,777 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646191,136 - 195,279 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RDH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,166,510 - 21,170,897 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,166,869 - 21,170,913 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2522,646,730 - 22,650,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RDH5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,667,461 - 51,672,386 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,668,803 - 51,672,192 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037194,322,273 - 194,327,136 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rdh5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480212,290,688 - 12,304,712 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480212,293,578 - 12,299,981 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000015493   ⟹   ENSPPAP00000003369
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,911,309 - 33,916,301 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000015539   ⟹   ENSPPAP00000003379
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,914,402 - 33,919,974 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000015546   ⟹   ENSPPAP00000003380
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,916,401 - 33,920,082 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000015557   ⟹   ENSPPAP00000003382
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,916,497 - 33,920,506 (-)Ensembl
RefSeq Acc Id: XM_063593043   ⟹   XP_063449113
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,603,587 - 38,608,452 (-)NCBI
RefSeq Acc Id: XM_063593044   ⟹   XP_063449114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21038,603,587 - 38,608,452 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063449113 (Get FASTA)   NCBI Sequence Viewer  
  XP_063449114 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003369.1
  ENSPPAP00000003379.1
  ENSPPAP00000003382.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000003369   ⟸   ENSPPAT00000015493
RefSeq Acc Id: ENSPPAP00000003382   ⟸   ENSPPAT00000015557
RefSeq Acc Id: ENSPPAP00000003380   ⟸   ENSPPAT00000015546
RefSeq Acc Id: ENSPPAP00000003379   ⟸   ENSPPAT00000015539
RefSeq Acc Id: XP_063449113   ⟸   XM_063593043
- UniProtKB: A0A2R8ZEU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449114   ⟸   XM_063593044
- UniProtKB: A0A2R8ZEU3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014135 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015493.1 UniProtKB/TrEMBL
  ENSPPAT00000015539.1 UniProtKB/TrEMBL
  ENSPPAT00000015557.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro BLOC1S1 UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
KEGG Report pps:100988391 UniProtKB/TrEMBL
NCBI Gene RDH5 ENTREZGENE
PANTHER BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 UniProtKB/TrEMBL
  PTHR13073 UniProtKB/TrEMBL
  RETINOL DEHYDROGENASE 5 UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  GCN5L1 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A2R8ZED7_PANPA UniProtKB/TrEMBL
  A0A2R8ZEU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZEV2_PANPA UniProtKB/TrEMBL