RFC2 (replication factor C subunit 2) - Rat Genome Database

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Gene: RFC2 (replication factor C subunit 2) Pan paniscus
Analyze
Symbol: RFC2
Name: replication factor C subunit 2
RGD ID: 12007918
Description: ENCODES a protein that exhibits DNA clamp loader activity (ortholog); single-stranded DNA helicase activity (ortholog); INVOLVED IN DNA duplex unwinding (inferred); DNA repair (inferred); DNA replication (inferred); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); genetic disease (ortholog); FOUND IN DNA replication factor C complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2690,644,647 - 90,667,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17138,909,280 - 138,931,940 (+)NCBINHGRI_mPanPan1
PanPan1.1781,378,937 - 81,401,937 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl781,378,937 - 81,401,937 (-)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RFC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2690,644,647 - 90,667,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17138,909,280 - 138,931,940 (+)NCBINHGRI_mPanPan1
PanPan1.1781,378,937 - 81,401,937 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl781,378,937 - 81,401,937 (-)Ensemblpanpan1.1panPan2
RFC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,231,502 - 74,254,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl774,231,499 - 74,254,458 (-)EnsemblGRCh38hg38GRCh38
GRCh37773,645,832 - 73,668,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,283,768 - 73,306,674 (-)NCBINCBI36Build 36hg18NCBI36
Build 34773,090,484 - 73,113,389NCBI
Celera769,125,398 - 69,148,304 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef769,527,267 - 69,550,345 (-)NCBIHuRef
CHM1_1773,790,894 - 73,813,879 (-)NCBICHM1_1
T2T-CHM13v2.0775,433,796 - 75,456,693 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,978,904 - 73,001,860 (-)NCBI
Rfc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395134,611,544 - 134,627,182 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5134,610,220 - 134,630,659 (+)EnsemblGRCm39 Ensembl
GRCm385134,582,690 - 134,598,328 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,581,366 - 134,601,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,058,560 - 135,074,198 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365134,867,317 - 134,882,955 (+)NCBIMGSCv36mm8
Celera5131,590,738 - 131,606,377 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.68NCBI
Rfc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,756,920 - 27,770,049 (-)NCBIGRCr8
mRatBN7.21222,120,449 - 22,133,576 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,120,010 - 22,133,557 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1223,263,632 - 23,276,828 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,874,713 - 23,887,909 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,941,263 - 22,954,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,130,375 - 25,143,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,130,377 - 25,143,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,130,769 - 27,143,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,185,550 - 23,198,655 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11223,046,380 - 23,053,601 (-)NCBI
Celera1223,884,376 - 23,897,525 (-)NCBICelera
Cytogenetic Map12q12NCBI
Rfc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545613,659,157 - 13,671,181 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545613,659,122 - 13,671,405 (+)NCBIChiLan1.0ChiLan1.0
RFC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,119,203 - 6,159,293 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,119,164 - 6,160,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,819,017 - 7,857,620 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.065,935,190 - 5,973,800 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl65,951,322 - 5,974,387 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.165,926,219 - 5,964,926 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,873,708 - 5,912,408 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,037,183 - 6,075,802 (+)NCBIUU_Cfam_GSD_1.0
Rfc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344130,756,864 - 130,772,906 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365433,263,878 - 3,279,667 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365433,263,661 - 3,273,178 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RFC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl311,373,492 - 11,392,695 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1311,373,489 - 11,392,690 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2311,056,709 - 11,068,698 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RFC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,818,606 - 8,846,929 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl288,818,650 - 8,847,865 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660707,734,642 - 7,758,689 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rfc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474013,737,310 - 13,748,821 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474013,737,225 - 13,748,876 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058723   ⟹   ENSPPAP00000035834
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl781,378,937 - 81,401,937 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000058726   ⟹   ENSPPAP00000035837
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl781,379,379 - 81,397,865 (-)Ensembl
RefSeq Acc Id: XM_003815554   ⟹   XP_003815602
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2690,644,691 - 90,667,307 (+)NCBI
NHGRI_mPanPan17138,909,327 - 138,931,940 (+)NCBI
PanPan1.1781,378,937 - 81,401,937 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034951393   ⟹   XP_034807284
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2690,644,647 - 90,667,307 (+)NCBI
NHGRI_mPanPan17138,909,280 - 138,931,940 (+)NCBI
RefSeq Acc Id: XM_034951396   ⟹   XP_034807287
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2690,644,835 - 90,667,307 (+)NCBI
NHGRI_mPanPan17138,909,425 - 138,931,940 (+)NCBI
RefSeq Acc Id: XM_063605861   ⟹   XP_063461931
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2690,644,690 - 90,665,202 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003815602 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807284 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807287 (Get FASTA)   NCBI Sequence Viewer  
  XP_063461931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035834
  ENSPPAP00000035834.1
  ENSPPAP00000035837.1
Reference Protein Sequences
RefSeq Acc Id: XP_003815602   ⟸   XM_003815554
- Peptide Label: isoform X3
- UniProtKB: A0A2R9C1P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000035837   ⟸   ENSPPAT00000058726
RefSeq Acc Id: ENSPPAP00000035834   ⟸   ENSPPAT00000058723
RefSeq Acc Id: XP_034807284   ⟸   XM_034951393
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034807287   ⟸   XM_034951396
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063461931   ⟸   XM_063605861
- Peptide Label: isoform X2
Protein Domains
Magnesium chelatase ChlI-like catalytic   Replication factor C C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040698 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058723.1 UniProtKB/TrEMBL
  ENSPPAT00000058726.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  1.20.272.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DNA_pol3_clamp-load_cplx_C UniProtKB/TrEMBL
  Mg_chelatse_chII-like_cat_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Rep_factorC_C UniProtKB/TrEMBL
  RFC_lid UniProtKB/TrEMBL
KEGG Report pps:100971331 UniProtKB/TrEMBL
NCBI Gene RFC2 ENTREZGENE
PANTHER REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT UniProtKB/TrEMBL
  REPLICATION FACTOR C SUBUNIT 2 UniProtKB/TrEMBL
Pfam Mg_chelatase UniProtKB/TrEMBL
  Rep_fac_C UniProtKB/TrEMBL
Superfamily-SCOP SSF48019 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9C1P3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C271_PANPA UniProtKB/TrEMBL