RIMKLB (ribosomal modification protein rimK like family member B) - Rat Genome Database

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Gene: RIMKLB (ribosomal modification protein rimK like family member B) Pan paniscus
Analyze
Symbol: RIMKLB
Name: ribosomal modification protein rimK like family member B
RGD ID: 12007123
Description: ENCODES a protein that exhibits citrate-L-glutamate ligase activity (ortholog); INVOLVED IN protein modification process (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 21 (ortholog); genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-citrylglutamate synthase B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,207,022 - 14,310,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,182,783 - 14,310,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,752,509 - 8,869,226 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,980,325 - 9,083,140 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,999,423 - 9,077,179 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RIMKLB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,207,022 - 14,310,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,182,783 - 14,310,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,752,509 - 8,869,226 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,980,325 - 9,083,140 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,999,423 - 9,077,179 (+)Ensemblpanpan1.1panPan2
RIMKLB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,668,638 - 8,783,091 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,681,600 - 8,783,095 (+)EnsemblGRCh38hg38GRCh38
GRCh37128,834,196 - 8,935,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,741,785 - 8,821,054 (+)NCBINCBI36Build 36hg18NCBI36
Celera1210,388,117 - 10,467,384 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,632,397 - 8,711,651 (+)NCBIHuRef
CHM1_1128,819,474 - 8,898,746 (+)NCBICHM1_1
T2T-CHM13v2.0128,647,354 - 8,766,437 (+)NCBIT2T-CHM13v2.0
Rimklb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,424,255 - 122,464,021 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,424,255 - 122,475,720 (-)EnsemblGRCm39 Ensembl
GRCm386122,447,296 - 122,487,062 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,447,296 - 122,498,761 (-)EnsemblGRCm38mm10GRCm38
MGSCv376122,403,627 - 122,436,323 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,419,882 - 122,461,454 (-)NCBIMGSCv36mm8
Celera6124,249,271 - 124,268,350 (-)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.55NCBI
Rimklb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,336,950 - 157,396,970 (-)NCBIGRCr8
mRatBN7.24155,664,392 - 155,706,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,664,375 - 155,706,711 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04155,258,241 - 155,292,809 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,260,103 - 155,275,161 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,283,614 - 222,318,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,904,485 - 158,950,642 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4144,485,390 - 144,527,333 (-)NCBICelera
Cytogenetic Map4q42NCBI
Rimklb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554136,306,414 - 6,346,278 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554136,298,833 - 6,362,812 (-)NCBIChiLan1.0ChiLan1.0
RIMKLB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,924,323 - 37,092,351 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,931,987 - 36,993,355 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,521,882 - 9,691,711 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,284,276 - 37,342,572 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,274,242 - 37,342,643 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,154,586 - 37,324,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,189,538 - 37,359,893 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,008,449 - 9,179,531 (+)NCBIUU_Cfam_GSD_1.0
Rimklb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494598,595,524 - 98,678,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493687093,012 - 164,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493687093,084 - 175,154 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIMKLB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,676,225 - 62,715,067 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1562,676,220 - 62,715,273 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,508,345 - 65,623,232 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIMKLB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,521,612 - 8,608,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,524,187 - 8,602,622 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089592,545 - 696,961 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rimklb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248604,811,449 - 4,844,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248604,811,449 - 4,861,470 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008960737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024931281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034935316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055095360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063592995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000035908   ⟹   ENSPPAP00000013238
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl128,999,423 - 9,076,708 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000035917   ⟹   ENSPPAP00000013247
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl129,013,044 - 9,077,179 (+)Ensembl
RefSeq Acc Id: XM_024931281   ⟹   XP_024787049
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,207,022 - 14,310,950 (+)NCBI
NHGRI_mPanPan11214,203,825 - 14,301,255 (+)NCBI
Mhudiblu_PPA_v0128,765,475 - 8,869,222 (+)NCBI
PanPan1.1128,980,325 - 9,083,140 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034935311   ⟹   XP_034791202
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,227,353 - 14,310,950 (+)NCBI
NHGRI_mPanPan11214,224,683 - 14,301,255 (+)NCBI
Mhudiblu_PPA_v0128,783,628 - 8,869,222 (+)NCBI
RefSeq Acc Id: XM_055095360   ⟹   XP_054951335
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,227,192 - 14,310,950 (+)NCBI
NHGRI_mPanPan11214,223,954 - 14,301,255 (+)NCBI
RefSeq Acc Id: XM_063592979   ⟹   XP_063449049
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592980   ⟹   XP_063449050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592981   ⟹   XP_063449051
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592982   ⟹   XP_063449052
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592983   ⟹   XP_063449053
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592984   ⟹   XP_063449054
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592985   ⟹   XP_063449055
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,225,374 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592986   ⟹   XP_063449056
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,225,000 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592987   ⟹   XP_063449057
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,227,353 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592988   ⟹   XP_063449058
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,653 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592989   ⟹   XP_063449059
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592990   ⟹   XP_063449060
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592991   ⟹   XP_063449061
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592992   ⟹   XP_063449062
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,224,960 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592993   ⟹   XP_063449063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,225,000 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592994   ⟹   XP_063449064
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,225,364 - 14,310,950 (+)NCBI
RefSeq Acc Id: XM_063592995   ⟹   XP_063449065
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,225,000 - 14,310,950 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_024787049   ⟸   XM_024931281
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL),   A0A2R9BJ99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034791202   ⟸   XM_034935311
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL),   A0A2R9BJ99 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000013247   ⟸   ENSPPAT00000035917
RefSeq Acc Id: ENSPPAP00000013238   ⟸   ENSPPAT00000035908
RefSeq Acc Id: XP_054951335   ⟸   XM_055095360
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449058   ⟸   XM_063592988
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449050   ⟸   XM_063592980
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449053   ⟸   XM_063592983
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449051   ⟸   XM_063592981
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449054   ⟸   XM_063592984
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449049   ⟸   XM_063592979
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449052   ⟸   XM_063592982
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063449060   ⟸   XM_063592990
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449062   ⟸   XM_063592992
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449059   ⟸   XM_063592989
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449061   ⟸   XM_063592991
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449056   ⟸   XM_063592986
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449065   ⟸   XM_063592995
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ACP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449063   ⟸   XM_063592993
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ACP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449064   ⟸   XM_063592994
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ACP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449055   ⟸   XM_063592985
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449057   ⟸   XM_063592987
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A7I7 (UniProtKB/TrEMBL)
Protein Domains
ATP-grasp


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029802 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAG00000037894 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035908.1 UniProtKB/TrEMBL
  ENSPPAT00000035917.1 UniProtKB/TrEMBL
  ENSPPAT00000052590.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.20 UniProtKB/TrEMBL
  3.40.50.20 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro ATP-grasp UniProtKB/TrEMBL
  ATP-grasp_RimK-type UniProtKB/TrEMBL
  ATP_grasp_subdomain_1 UniProtKB/TrEMBL
  RpS6_RimK/Lys_biosynth_LsyX UniProtKB/TrEMBL
KEGG Report pps:100974820 UniProtKB/TrEMBL
NCBI Gene RIMKLB ENTREZGENE
PANTHER BETA-CITRYLGLUTAMATE SYNTHASE B UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN UniProtKB/TrEMBL
Pfam RimK UniProtKB/TrEMBL
PROSITE ATP_GRASP UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A2R9A7I7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ACP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BJ99 ENTREZGENE, UniProtKB/TrEMBL