RNASE12 (ribonuclease A family member 12 (inactive)) - Rat Genome Database

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Gene: RNASE12 (ribonuclease A family member 12 (inactive)) Pan paniscus
Analyze
Symbol: RNASE12
Name: ribonuclease A family member 12 (inactive)
RGD ID: 12006610
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); RNA nuclease activity (inferred); INVOLVED IN defense response to Gram-positive bacterium (inferred); ASSOCIATED WITH purine nucleoside phosphorylase deficiency (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable inactive ribonuclease-like protein 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,090,010 - 22,091,224 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,306,497 - 21,307,711 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,455,095 - 1,455,777 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,512,240 - 19,512,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,512,434 - 19,512,877 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNASE12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,090,010 - 22,091,224 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,306,497 - 21,307,711 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,455,095 - 1,455,777 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,512,240 - 19,512,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,512,434 - 19,512,877 (-)Ensemblpanpan1.1panPan2
RNASE12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,590,073 - 20,591,376 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,590,073 - 20,591,376 (-)EnsemblGRCh38hg38GRCh38
GRCh371421,058,232 - 21,059,535 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,128,279 - 20,128,722 (-)NCBINCBI36Build 36hg18NCBI36
Celera14919,115 - 919,858 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,179,194 - 1,179,937 (-)NCBIHuRef
CHM1_11421,060,260 - 21,061,003 (-)NCBICHM1_1
T2T-CHM13v2.01414,787,199 - 14,788,502 (-)NCBIT2T-CHM13v2.0
Rnase12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,294,155 - 51,294,699 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,294,155 - 51,295,118 (-)EnsemblGRCm39 Ensembl
GRCm381451,056,698 - 51,057,242 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,056,698 - 51,057,661 (-)EnsemblGRCm38mm10GRCm38
MGSCv371451,676,458 - 51,676,895 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,978,734 - 49,979,171 (-)NCBIMGSCv36mm8
Celera1447,334,352 - 47,334,789 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.36NCBI
Rnase12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,749,291 - 26,761,261 (-)NCBIGRCr8
mRatBN7.21524,275,767 - 24,286,843 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,275,774 - 24,276,702 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,046,933 - 27,047,968 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,006,347 - 28,007,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,255,488 - 26,256,523 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,981,044 - 27,993,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,981,226 - 27,981,663 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,813,813 - 31,814,848 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,035,657 - 27,036,094 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,051,357 - 27,051,794 (-)NCBI
Celera1524,595,824 - 24,596,261 (-)NCBICelera
Cytogenetic Map15p14NCBI
Rnase12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,399,335 - 1,400,310 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,399,335 - 1,400,310 (-)NCBIChiLan1.0ChiLan1.0
RNASE12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,903,824 - 17,906,219 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,903,983 - 17,906,201 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,386,238 - 18,388,665 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,160,555 - 18,162,983 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,160,721 - 18,162,934 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,842,557 - 17,844,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,898,192 - 17,900,629 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,026,824 - 18,029,255 (-)NCBIUU_Cfam_GSD_1.0
RNASE12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,340,268 - 78,340,705 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,333,025 - 78,340,906 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,359,308 - 83,367,908 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNASE12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,112,741 - 21,131,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,112,948 - 21,113,391 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,316,253 - 25,317,185 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnase12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248254,584,782 - 4,585,219 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248254,584,114 - 4,585,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008964118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000042287   ⟹   ENSPPAP00000019519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1419,512,434 - 19,512,877 (-)Ensembl
RefSeq Acc Id: XM_008964118   ⟹   XP_008962366
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21522,090,010 - 22,091,224 (-)NCBI
NHGRI_mPanPan11421,306,497 - 21,307,711 (-)NCBI
Mhudiblu_PPA_v0141,455,095 - 1,455,777 (-)NCBI
PanPan1.11419,512,240 - 19,512,971 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008962366 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000019519.1
RefSeq Acc Id: XP_008962366   ⟸   XM_008964118
- Sequence:
Ensembl Acc Id: ENSPPAP00000019519   ⟸   ENSPPAT00000042287
Protein Domains
Ribonuclease A-domain


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032974 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042287.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.130.10 UniProtKB/TrEMBL
InterPro RNaseA UniProtKB/TrEMBL
  RNaseA-like_dom_sf UniProtKB/TrEMBL
  RNaseA_domain UniProtKB/TrEMBL
KEGG Report pps:103785005 UniProtKB/TrEMBL
NCBI Gene RNASE12 ENTREZGENE
PANTHER PTHR11437 UniProtKB/TrEMBL
  PTHR11437:SF20 UniProtKB/TrEMBL
Pfam RnaseA UniProtKB/TrEMBL
PRINTS RIBONUCLEASE UniProtKB/TrEMBL
SMART RNAse_Pc UniProtKB/TrEMBL
Superfamily-SCOP SSF54076 UniProtKB/TrEMBL
UniProt A0A2R9AWY8_PANPA UniProtKB/TrEMBL