TMEM63A (transmembrane protein 63A) - Rat Genome Database

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Gene: TMEM63A (transmembrane protein 63A) Pan paniscus
Analyze
Symbol: TMEM63A
Name: transmembrane protein 63A
RGD ID: 12005163
Description: ENCODES a protein that exhibits calcium-activated cation channel activity (inferred); mechanosensitive monoatomic ion channel activity (inferred); nucleic acid binding (inferred); INVOLVED IN monoatomic cation transmembrane transport (inferred); monoatomic ion transmembrane transport (inferred); ASSOCIATED WITH Disease Progression (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN early endosome membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CSC1-like protein 1
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2123,652,821 - 23,692,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1123,600,025 - 23,639,447 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01201,306,608 - 201,344,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11206,302,729 - 206,344,760 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1206,307,554 - 206,343,458 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TMEM63A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2123,652,821 - 23,692,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1123,600,025 - 23,639,447 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01201,306,608 - 201,344,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11206,302,729 - 206,344,760 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1206,307,554 - 206,343,458 (-)Ensemblpanpan1.1panPan2
TMEM63A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,840,556 - 225,882,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1225,845,536 - 225,882,380 (-)EnsemblGRCh38hg38GRCh38
GRCh371226,033,237 - 226,070,080 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361224,099,863 - 224,136,671 (-)NCBINCBI36Build 36hg18NCBI36
Celera1199,224,296 - 199,261,462 (-)NCBICelera
Cytogenetic Map1q42.12NCBI
HuRef1196,550,933 - 196,588,105 (-)NCBIHuRef
CHM1_11227,305,554 - 227,342,737 (-)NCBICHM1_1
T2T-CHM13v2.01225,028,653 - 225,070,125 (-)NCBIT2T-CHM13v2.0
Tmem63a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,769,899 - 180,802,671 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1180,769,909 - 180,802,677 (+)EnsemblGRCm39 Ensembl
GRCm381180,942,286 - 180,975,106 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,942,344 - 180,975,112 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,872,649 - 182,905,235 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361182,779,193 - 182,811,779 (+)NCBIMGSCv36mm8
Celera1188,007,992 - 188,040,911 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map184.46NCBI
Tmem63a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81395,194,323 - 95,227,944 (+)NCBIGRCr8
mRatBN7.21392,662,872 - 92,696,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1392,663,968 - 92,696,183 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1395,168,759 - 95,201,496 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01396,568,688 - 96,601,427 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01393,743,385 - 93,776,126 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01399,219,585 - 99,253,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,220,510 - 99,253,316 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,217,467 - 104,250,973 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,671,527 - 96,704,177 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11396,860,142 - 96,893,106 (+)NCBI
Celera1392,206,402 - 92,238,798 (+)NCBICelera
Cytogenetic Map13q26NCBI
TMEM63A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1738,936,989 - 38,964,349 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl738,937,041 - 38,964,345 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha738,421,464 - 38,446,556 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0738,770,941 - 38,798,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl738,771,006 - 38,798,314 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1738,613,007 - 38,638,098 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0738,621,158 - 38,646,233 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0738,890,919 - 38,916,009 (+)NCBIUU_Cfam_GSD_1.0
Tmem63a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934452,056,943 - 52,093,748 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365262,652,111 - 2,690,451 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365262,653,556 - 2,690,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM63A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1013,769,605 - 13,814,020 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11013,771,795 - 13,814,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21015,975,250 - 16,015,708 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM63A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1253,887,535 - 3,924,422 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl253,890,581 - 3,922,944 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660553,893,879 - 3,930,728 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046532   ⟹   ENSPPAP00000023707
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1206,307,554 - 206,343,458 (-)Ensembl
RefSeq Acc Id: XM_008967793   ⟹   XP_008966041
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2123,652,822 - 23,689,289 (+)NCBI
NHGRI_mPanPan1123,600,025 - 23,639,447 (+)NCBI
Mhudiblu_PPA_v01201,306,608 - 201,344,627 (-)NCBI
PanPan1.11206,307,554 - 206,344,760 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034947815   ⟹   XP_034803706
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2123,652,832 - 23,692,349 (+)NCBI
NHGRI_mPanPan1123,600,025 - 23,639,447 (+)NCBI
Mhudiblu_PPA_v01201,306,608 - 201,344,627 (-)NCBI
RefSeq Acc Id: XM_063596536   ⟹   XP_063452606
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2123,656,082 - 23,689,289 (+)NCBI
RefSeq Acc Id: XM_063596551   ⟹   XP_063452621
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2123,652,821 - 23,689,289 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008966041 (Get FASTA)   NCBI Sequence Viewer  
  XP_034803706 (Get FASTA)   NCBI Sequence Viewer  
  XP_063452606 (Get FASTA)   NCBI Sequence Viewer  
  XP_063452621 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023707.1
Reference Protein Sequences
RefSeq Acc Id: XP_008966041   ⟸   XM_008967793
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034803706   ⟸   XM_034947815
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000023707   ⟸   ENSPPAT00000046532
RefSeq Acc Id: XP_063452621   ⟸   XM_063596551
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063452606   ⟸   XM_063596536
- Peptide Label: isoform X1
Protein Domains
CSC1/OSCA1-like 7TM region   CSC1/OSCA1-like cytosolic   CSC1/OSCA1-like N-terminal transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035003 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046532.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Csc1-like UniProtKB/TrEMBL
  Csc1_N UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PHM7_cyt UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RSN1_7TM UniProtKB/TrEMBL
KEGG Report pps:100995512 UniProtKB/TrEMBL
NCBI Gene TMEM63A ENTREZGENE
PANTHER PTHR13018 UniProtKB/TrEMBL
  PTHR13018:SF24 UniProtKB/TrEMBL
Pfam PHM7_cyt UniProtKB/TrEMBL
  RSN1_7TM UniProtKB/TrEMBL
  RSN1_TM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A2R9B2E1 ENTREZGENE, UniProtKB/TrEMBL