SPEM2 (SPEM family member 2) - Rat Genome Database

Name: SPEM2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: SPEM2 (SPEM family member 2) Pan paniscus

Analyze

Symbol:

SPEM2

Name:

SPEM family member 2

RGD ID:

11994845

Description:

ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome 2A (ortholog); dyskeratosis congenita (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC100980823; uncharacterized protein C17orf74; uncharacterized protein LOC100980823; uncharacterized protein SPEM2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SPEM2 (SPEM family member 2)	NCBI	Ortholog
Mus musculus (house mouse):	Spem2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Spem2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Spem2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SPEM2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Spem2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SPEM2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SPEM2 (SPEM family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	15,019,413 - 15,024,166 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	16,985,222 - 16,989,970 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	7,458,605 - 7,461,545 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	7,445,958 - 7,447,907 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,449,092 - 7,453,041 (+)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	17	7,445,958 - 7,447,907 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

common variable immunodeficiency (ISO)

congenital myasthenic syndrome 2A (ISO)

dyskeratosis congenita (ISO)

intellectual disability (ISO)

Li-Fraumeni syndrome (ISO)

very long chain acyl-CoA dehydrogenase deficiency (ISO)

Weissenbacher-Zweymuller syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

References

Genomics

Comparative Map Data

SPEM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	15,019,413 - 15,024,166 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	16,985,222 - 16,989,970 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	7,458,605 - 7,461,545 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	7,445,958 - 7,447,907 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,449,092 - 7,453,041 (+)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	17	7,445,958 - 7,447,907 (+)	Ensembl	panpan1.1		panPan2

SPEM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	7,425,616 - 7,427,568 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	7,425,616 - 7,427,568 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	7,328,935 - 7,330,887 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,269,659 - 7,271,611 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	7,354,821 - 7,356,773 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,222,961 - 7,224,913 (+)	NCBI		HuRef
CHM1_1	17	7,338,027 - 7,339,979 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	7,329,669 - 7,331,621 (+)	NCBI		T2T-CHM13v2.0

Spem2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,707,386 - 69,709,313 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	69,707,392 - 69,709,291 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	69,816,560 - 69,818,487 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,816,566 - 69,818,465 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,630,068 - 69,631,942 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	69,632,761 - 69,634,635 (-)	NCBI		MGSCv36	mm8
Celera	11	77,377,527 - 77,379,401 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.89	NCBI

Spem2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	55,035,892 - 55,037,790 (-)	NCBI		GRCr8
mRatBN7.2	10	54,537,168 - 54,539,026 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	54,537,174 - 54,539,058 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	59,199,677 - 59,201,528 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,688,243 - 58,690,094 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	54,195,894 - 54,197,745 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	56,424,164 - 56,426,012 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	56,424,164 - 56,426,012 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	56,169,247 - 56,171,081 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,638,639 - 56,640,472 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	53,691,427 - 53,693,278 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Spem2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	9,498,541 - 9,500,466 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	9,493,708 - 9,500,466 (-)	NCBI	ChiLan1.0	ChiLan1.0

SPEM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,357,302 - 32,359,197 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,357,336 - 32,359,129 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,495,333 - 32,497,293 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,462,905 - 32,464,865 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,462,999 - 32,464,797 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,428,139 - 32,430,099 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,386,871 - 32,388,831 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,564,139 - 32,566,099 (+)	NCBI		UU_Cfam_GSD_1.0

Spem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	47,232,222 - 47,236,485 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	708,799 - 710,604 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	708,694 - 710,810 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPEM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,728,826 - 52,730,822 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,729,001 - 52,731,131 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,021,617 - 55,023,538 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPEM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	6,800,970 - 6,803,726 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	6,801,835 - 6,803,655 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	14,604,873 - 14,607,257 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003810087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055102306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000037112 ⟹ ENSPPAP00000014428

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	7,449,092 - 7,453,041 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000056458 ⟹ ENSPPAP00000033582

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	7,445,958 - 7,447,907 (+)	Ensembl

RefSeq Acc Id:

XM_003810087 ⟹ XP_003810135

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	15,021,422 - 15,024,166 (+)	NCBI
NHGRI_mPanPan1	17	16,987,202 - 16,989,970 (+)	NCBI
Mhudiblu_PPA_v0	17	7,458,605 - 7,461,366 (+)	NCBI
PanPan1.1	17	7,445,958 - 7,447,907 (+)	NCBI

Sequence:

show sequence

GAGTGCAGTGTGGGTTGGGGCCGGGGGTGGGGGCAGAGGGGGGTGGCCCAGGTGGCCCTAGGAC
CCCCCCTCCATGGAAAACCAGCTATGGCATAACACCGTGAGATGTTGCAATCAATACCAAGAAA
GCCCCCACGATGCCGAGGACATCTTACTCCTGCTGCTGGGCCTCATCGTTCTTGTCAACATTGG
CATCAACGTGGCAACTATGATGTGGCATGGACTCCAGAACGCCTTAGACAAGATGATTGATTGG
GCTACTCAGAAAAATGAAATTCAGGCCAGTGAAAGTCCCCCAAGTGGTCCCCCAGACAAGGCTC
AGGATGTCCACATCCACTGCATCCTGGACCCTGTGCAGGTGAAGATGTCCCGACCCACGCAGTA
CTCCTCTTTCTCCTGCCACCATTTCTCCAACCATCACAGTAGCAGTCTTCTTCGCTGTGTTCGT
CGCCACCGCCGCCACCGCCGTTGTCGCCGTCGCTGCTGCAACCACCAGCAGCGGCCGCAGAACT
ACAGACAAATCCCCCATAGCCGCTCAGTCTTCCGTAACCCACATCGCAGCCAAAAGATGTCACA
ACTACACCGAGTGCCTTTCTTTGATCAGGAGGACCTGGATTCCTACCTGGAGGAGGAGGACAAC
CTGCCCTTCCCGTATCCCAAGTACCCACGTCGCGGCTGGGGTGGGTTTTATCAGAGAGCGGGCC
TGCCCTCCAATGTGGGGCTGTGGGGCCACCAGGGTGGTATCCTGGCCAGTCTGCCACCACCCTC
TCTCTACCTGTCACCTGAGCTGCGCTGCATGCCCAAGCGTGTAGAGGCCAAGTCCGAGCTGAGG
CTGCAGTCCTGTGGGCGCCACGGTTCCCAGTCCCGACTGTGGGGCAATGTGGAGGCTGAGCAGT
GGGCCTCGTCTCCACCACCTCCCCACCGGCTGCCCCCTAACCCCTCTTGGGTCCCCGTGGGGCA
CAGCCCTTACCCCTCAGTGGGCTGGATGCTGTATGACTCCTGGGATCAGCGGCGTCGTGGCATG
GAGGGCTTTGAGCGCCCCCCTGCCTTGGTGTCCCGGAACGCCCGGCCTGAGGTCCAGGGCTGCC
GGGAGCACCACTCCCTACAGTCCCACCGGCAGAGCCTGCTTGGTCACGCCTATGGCCAGTCCCA
CCGCAGTCCCCACCCATCCACGGAACCCTTGGGCTACAGCTCCCGGGACCCCCATGAGGTGCGG
CGTCGGGCAGCTGACTGGGCTGAGGCTCTGCCCGCCTGGCGTCCTCTGACTACCTCTGCCTCCC
TCACGGTGTTGGACGAGGCCTCCCACCAACGGACCCCAGCTCCAAGCTCAGTGCTGGTCCCCCA
TTCCTCCCAGCCCTGGCCCAAAGTCCAGGCTGCGGATCCCGCCCCTCCCCCGACCATGTTCGTC
CCACTCAGCCGGAATCCAGGGGGCAATGCCAACTACCAGGTGTATGACAGCCTGGAGCTGAAGC
GGCAGGTGCAGAAGAGCAGAGCCAGGTCCAGCTCACTGCCACCGGCTTCCACCTCCACCTTGAG
GCCCTCTCTGCACAGGAGCCAGACCGAGAAACTCAACTGACCAGCAGGCGGATGTGGGGTGTGG
GGCAGGGCATGGAGGGAGAGGAATAAAGAGAAACAGAGTCCAGGAAA

hide sequence

RefSeq Acc Id:

XM_055102306 ⟹ XP_054958281

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	15,019,413 - 15,024,166 (+)	NCBI
NHGRI_mPanPan1	17	16,985,222 - 16,989,970 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003810135	(Get FASTA)	NCBI Sequence Viewer
	XP_054958281	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000033582
	ENSPPAP00000033582.1

RefSeq Acc Id:	XP_003810135 ⟸ XM_003810087
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BV75 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENQLWHNTVRCCNQYQESPHDAEDILLLLLGLIVLVNIGINVATMMWHGLQNALDKMIDWATQ KNEIQASESPPSGPPDKAQDVHIHCILDPVQVKMSRPTQYSSFSCHHFSNHHSSSLLRCVRRHR RHRRCRRRCCNHQQRPQNYRQIPHSRSVFRNPHRSQKMSQLHRVPFFDQEDLDSYLEEEDNLPF PYPKYPRRGWGGFYQRAGLPSNVGLWGHQGGILASLPPPSLYLSPELRCMPKRVEAKSELRLQS CGRHGSQSRLWGNVEAEQWASSPPPPHRLPPNPSWVPVGHSPYPSVGWMLYDSWDQRRRGMEGF ERPPALVSRNARPEVQGCREHHSLQSHRQSLLGHAYGQSHRSPHPSTEPLGYSSRDPHEVRRRA ADWAEALPAWRPLTTSASLTVLDEASHQRTPAPSSVLVPHSSQPWPKVQAADPAPPPTMFVPLS RNPGGNANYQVYDSLELKRQVQKSRARSSSLPPASTSTLRPSLHRSQTEKLN hide sequence

RefSeq Acc Id:

ENSPPAP00000033582 ⟸ ENSPPAT00000056458

RefSeq Acc Id:

ENSPPAP00000014428 ⟸ ENSPPAT00000037112

RefSeq Acc Id:	XP_054958281 ⟸ XM_055102306
- Peptide Label:	isoform X2

Protein Domains

Spermatid maturation protein 1 N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000030365	Ensembl
	ENSPPAG00000039663	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000056458.1	UniProtKB/TrEMBL
InterPro	SPEM1_N	UniProtKB/TrEMBL
KEGG Report	pps:100980823	UniProtKB/TrEMBL
NCBI Gene	LOC100980823	ENTREZGENE
PANTHER	SPEM FAMILY MEMBER 2	UniProtKB/TrEMBL
	SPERMATID MATURATION PROTEIN 1	UniProtKB/TrEMBL
Pfam	Spem1	UniProtKB/TrEMBL
UniProt	A0A2R9BV75	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-08	SPEM2	SPEM family member 2	LOC100980823	uncharacterized protein C17orf74	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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