UNC5C (unc-5 netrin receptor C) - Rat Genome Database

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Gene: UNC5C (unc-5 netrin receptor C) Pan paniscus
Analyze
Symbol: UNC5C
Name: unc-5 netrin receptor C
RGD ID: 11994563
Description: ENCODES a protein that exhibits axon guidance receptor activity (inferred); netrin receptor activity (inferred); netrin receptor activity involved in chemorepulsion (inferred); INVOLVED IN anterior/posterior axon guidance (ortholog); apoptotic process (ortholog); axon guidance (ortholog); ASSOCIATED WITH genetic disease (ortholog); renal cell carcinoma (ortholog); FOUND IN axon (inferred); cytoplasm (inferred); dendrite (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: netrin receptor UNC5C; unc-5 homolog C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2393,198,579 - 93,586,730 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1493,477,466 - 93,865,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0487,527,262 - 87,921,351 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1498,198,831 - 98,589,857 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl498,205,554 - 98,587,888 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UNC5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2393,198,579 - 93,586,730 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1493,477,466 - 93,865,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0487,527,262 - 87,921,351 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1498,198,831 - 98,589,857 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl498,205,554 - 98,587,888 (-)Ensemblpanpan1.1panPan2
UNC5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38495,162,504 - 95,548,973 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl495,162,504 - 95,549,206 (-)EnsemblGRCh38hg38GRCh38
GRCh37496,083,655 - 96,470,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36496,308,712 - 96,689,185 (-)NCBINCBI36Build 36hg18NCBI36
Build 34496,446,866 - 96,827,340NCBI
Celera493,380,311 - 93,766,978 (-)NCBICelera
Cytogenetic Map4q22.3NCBI
HuRef491,820,282 - 92,206,879 (-)NCBIHuRef
CHM1_1496,060,693 - 96,447,078 (-)NCBICHM1_1
T2T-CHM13v2.0498,477,165 - 98,864,110 (-)NCBIT2T-CHM13v2.0
Unc5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393141,171,360 - 141,540,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3141,170,977 - 141,540,685 (+)EnsemblGRCm39 Ensembl
GRCm383141,465,564 - 141,834,924 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3141,465,216 - 141,834,924 (+)EnsemblGRCm38mm10GRCm38
MGSCv373141,128,528 - 141,497,886 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363141,402,951 - 141,772,309 (+)NCBIMGSCv36mm8
Celera3147,889,997 - 148,247,699 (+)NCBICelera
Cytogenetic Map3H1NCBI
cM Map365.57NCBI
Unc5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82232,854,352 - 233,208,482 (+)NCBIGRCr8
mRatBN7.22230,180,353 - 230,535,219 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2230,180,951 - 230,535,217 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2237,924,292 - 238,290,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02235,817,330 - 236,183,687 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02230,681,978 - 231,048,343 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02247,045,813 - 247,397,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2247,248,407 - 247,397,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02265,573,406 - 265,926,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42239,365,109 - 239,721,231 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12239,351,848 - 239,707,971 (+)NCBI
Celera2222,239,483 - 222,591,078 (+)NCBICelera
Cytogenetic Map2q44NCBI
Unc5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554055,797,590 - 5,950,544 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554055,791,286 - 6,049,952 (-)NCBIChiLan1.0ChiLan1.0
UNC5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13217,981,286 - 18,333,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3217,987,464 - 18,333,602 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3223,609,404 - 23,959,891 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03218,164,222 - 18,513,849 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3218,167,485 - 18,513,818 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13218,134,124 - 18,485,245 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03217,955,873 - 18,306,960 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03221,584,814 - 21,936,742 (+)NCBIUU_Cfam_GSD_1.0
Unc5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530123,396,564 - 23,746,350 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366872,607,112 - 2,756,094 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366872,600,635 - 2,951,407 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8124,142,030 - 124,530,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18124,149,364 - 124,533,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UNC5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1743,405,666 - 43,786,436 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603721,777,546 - 22,164,042 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475723,151,485 - 23,537,706 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475723,145,200 - 23,537,812 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000060375   ⟹   ENSPPAP00000037475
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,205,554 - 98,587,888 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060385   ⟹   ENSPPAP00000037485
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,205,554 - 98,373,102 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060388   ⟹   ENSPPAP00000037488
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,205,554 - 98,369,698 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060395   ⟹   ENSPPAP00000037495
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,205,554 - 98,336,380 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060398   ⟹   ENSPPAP00000037498
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,205,554 - 98,316,026 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060406   ⟹   ENSPPAP00000037506
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl498,284,141 - 98,587,888 (-)Ensembl
RefSeq Acc Id: XM_003829912   ⟹   XP_003829960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2393,198,579 - 93,586,728 (-)NCBI
NHGRI_mPanPan1493,477,466 - 93,865,725 (-)NCBI
Mhudiblu_PPA_v0487,527,262 - 87,921,350 (-)NCBI
PanPan1.1498,198,831 - 98,589,857 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008955313   ⟹   XP_008953561
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2393,198,579 - 93,586,730 (-)NCBI
NHGRI_mPanPan1493,477,466 - 93,865,726 (-)NCBI
Mhudiblu_PPA_v0487,527,262 - 87,921,351 (-)NCBI
PanPan1.1498,198,831 - 98,589,857 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003829960   ⟸   XM_003829912
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C6D2 (UniProtKB/TrEMBL),   A0A2R9C968 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008953561   ⟸   XM_008955313
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C968 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000037475   ⟸   ENSPPAT00000060375
RefSeq Acc Id: ENSPPAP00000037495   ⟸   ENSPPAT00000060395
RefSeq Acc Id: ENSPPAP00000037498   ⟸   ENSPPAT00000060398
RefSeq Acc Id: ENSPPAP00000037488   ⟸   ENSPPAT00000060388
RefSeq Acc Id: ENSPPAP00000037485   ⟸   ENSPPAT00000060385
RefSeq Acc Id: ENSPPAP00000037506   ⟸   ENSPPAT00000060406
Protein Domains
Ig-like   ZU5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060375.1 UniProtKB/TrEMBL
  ENSPPAT00000060385.1 UniProtKB/TrEMBL
  ENSPPAT00000060388.1 UniProtKB/TrEMBL
  ENSPPAT00000060395.1 UniProtKB/TrEMBL
  ENSPPAT00000060398.1 UniProtKB/TrEMBL
  ENSPPAT00000060406.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  2.60.220.30 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/TrEMBL
  Death_domain UniProtKB/TrEMBL
  Death_UNC5C UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  UNC5 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5_dom UniProtKB/TrEMBL
KEGG Report pps:100993093 UniProtKB/TrEMBL
NCBI Gene UNC5C ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  NETRIN RECEPTOR UNC5C UniProtKB/TrEMBL
  PTHR12582 UniProtKB/TrEMBL
  WRAPPER_REGA-1_KLINGON HOMOLOG UniProtKB/TrEMBL
Pfam Death UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
PRINTS TSP1REPEAT UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
SMART DEATH UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A2R9C6D2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C6E2_PANPA UniProtKB/TrEMBL
  A0A2R9C6F1_PANPA UniProtKB/TrEMBL
  A0A2R9C6G3_PANPA UniProtKB/TrEMBL
  A0A2R9C968 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C979_PANPA UniProtKB/TrEMBL