PRSS53 (serine protease 53) - Rat Genome Database

Name: PRSS53
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: PRSS53 (serine protease 53) Pan paniscus

Analyze

Symbol:

PRSS53

Name:

serine protease 53

RGD ID:

11993442

Description:

ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); genetic disease (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protease, serine 53

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRSS53 (serine protease 53)	NCBI	Ortholog
Mus musculus (house mouse):	Prss53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Prss53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prss53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRSS53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prss53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRSS53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRSS53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prss53 (serine protease 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	34,290,947 - 34,298,383 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	39,092,350 - 39,099,786 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	23,876,533 - 23,883,969 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	31,452,183 - 31,459,549 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	31,452,183 - 31,459,549 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

branched-chain keto acid dehydrogenase kinase deficiency (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (IEA)

Molecular Function

protein binding (ISO)

serine-type endopeptidase activity (IEA)

serine-type peptidase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PRSS53
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	34,290,947 - 34,298,383 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	39,092,350 - 39,099,786 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	23,876,533 - 23,883,969 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	31,452,183 - 31,459,549 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	31,452,183 - 31,459,549 (-)	Ensembl	panpan1.1		panPan2

PRSS53
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	31,083,437 - 31,088,943 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	31,083,437 - 31,089,628 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	31,094,758 - 31,100,264 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	31,002,246 - 31,007,631 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	29,197,373 - 29,202,758 (+)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	28,656,444 - 28,661,829 (-)	NCBI		HuRef
CHM1_1	16	32,412,046 - 32,417,431 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	31,470,865 - 31,476,371 (-)	NCBI		T2T-CHM13v2.0

Prss53
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	127,484,616 - 127,490,594 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	127,485,013 - 127,490,142 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	127,885,444 - 127,892,965 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,885,841 - 127,890,970 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	135,028,958 - 135,034,484 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	127,676,592 - 127,682,118 (-)	NCBI		MGSCv36	mm8
Celera	7	127,720,640 - 127,726,169 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	69.81	NCBI

Prss53
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	191,923,398 - 191,931,292 (-)	NCBI		GRCr8
mRatBN7.2	1	182,494,944 - 182,501,607 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	182,494,955 - 182,500,115 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	190,846,034 - 190,850,698 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	198,032,128 - 198,036,792 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	190,702,532 - 190,707,202 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	199,331,108 - 199,337,129 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	199,331,787 - 199,336,451 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	206,353,540 - 206,359,553 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	187,169,747 - 187,174,411 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	180,146,294 - 180,150,958 (-)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

Prss53
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	7,921,408 - 7,925,708 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	7,921,335 - 7,927,233 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRSS53
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	17,144,099 - 17,148,767 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	17,144,154 - 17,148,673 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	18,718,820 - 18,724,360 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,274,344 - 17,279,885 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	17,275,035 - 17,279,900 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	17,074,745 - 17,080,285 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	16,993,605 - 16,999,145 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,305,990 - 17,311,530 (+)	NCBI		UU_Cfam_GSD_1.0

Prss53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	125,354,227 - 125,360,148 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	13,452,456 - 13,457,629 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	13,452,418 - 13,457,948 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRSS53
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	17,391,219 - 17,396,885 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	17,390,801 - 17,396,885 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	17,721,343 - 17,727,571 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRSS53
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,771,033 - 27,778,544 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,771,384 - 27,776,516 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	1,690,087 - 1,696,864 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prss53
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	14,134,420 - 14,140,077 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	14,134,968 - 14,140,693 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003807492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008959633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008959634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063597568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063597569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000062007 ⟹ ENSPPAP00000039098

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	16	31,452,183 - 31,458,366 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000062009 ⟹ ENSPPAP00000039100

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	16	31,452,253 - 31,459,549 (-)	Ensembl

RefSeq Acc Id:

XM_003807492 ⟹ XP_003807540

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	34,291,158 - 34,297,389 (-)	NCBI
NHGRI_mPanPan1	16	39,092,350 - 39,099,601 (-)	NCBI
Mhudiblu_PPA_v0	16	23,877,710 - 23,883,969 (+)	NCBI
PanPan1.1	16	31,452,183 - 31,458,366 (-)	NCBI

Sequence:

show sequence

TGCTGGGATTACAGGCGTGAGCCACCATGCCCGGCCAGCATCTATAATATATGCTAAACCTTAC
CCACAGCTGCCTCTGTCTTGGGGTCAGGGTTCTTGAATGGTCTGGGCCAGCCTGAGTTAGGAGT
GGGAAGAGGAAGAGGAGGCACGTGCCAAAGTGTTCTTCCCGCCTGACCGAGTCCTCTGCGCCTG
TGAGGAAGGTGGGCACCACTGTCACCCTGTTTCCCGGGAAGCCAGCAGGCCCAGGGAGATACTG
GGATTTGCCAAAGGCTCACAGCGAGCAAGCAGCAATGGGTGCTGGCCCCTCACCACTCAGCCTG
GCACACACTGTCTCTGAGCAGACCTGGGAGAAGGCATGTGAAACCCACCTAGCCCTGGATGGAA
GAGAAGTGGGGGAGTGGAAATGAAAAGTGGGGACTGGGAGGAGCTGCCCACGTGCCCTCCATGG
TTCCAGGATGGCACTTTCATGCTGGGAGTGAGCTTGCCCTGTGCCAGGCTGTCATTGAGGCGTT
TTCCATTCAACAACTGTTTCTCAGACAAGGCACAGGCAGGTTAGCTCTCCCAGGCCACTCAAGT
AGTAAGGAAACAGATTTAAACCCAGACAGTTTGGCTCCACGGCTAAGGCCCAGAGAGGGGTGGT
GACAAGCCTAGGGTCACACAGCCACAGCCCCAGAGCTAGGAACTGCTGGCTAGGGCAAGCAGAC
AGCTGACTCCTAGCCAACTGGAGGTGGAGCAGAGGTGGAGCCAGGGAGACCCAGGTGGCCTCTC
TGAGAGTGGAGCACAGGTGGCAGAGTGGCCCGGGGCAGCATGAAGTGGTGCTGGGGCCCAGTGC
TGCTCATCGCGGGTGCCACGGTCCTCATGGAGGGTCTTCAAGCCGCTCAGCGTGCCTGTGGACA
GCGTGGCCCCGGCCCCCCCAAGCCTCAGGAGGGCAACACAGTCTCTGGCGAGTGGCCCTGGCAG
GCCAGTGTGAGGAGGCAAGGAGCCCACATCTGCAGCGGCTCCCTGGTGGCAGACACCTGGGTCC
TCACTGCTGCCCACTGCTTTGAAAAGGCAGCAGCAACAGAACTGAACTCCTGGTCAGTGGTCCT
GGGTTCTCTGCAGCGTGAGGGACTCAGCCCTGGGGCCGAAGAGGTGGGGGTGGCTGCCCTGCAG
TTGCCCAGGGCCTATAACCACTACAGCCAGGGCTCAGACCTGGCCCTGCTGCAGCTCGCCCACC
CCACGACCCACACACCCCTCTGCCTGCCCCAGCCTGTCCATCGCTTCCCCTTTGGAGCCTCCTG
CTGGGCCACTGGCTGGGATCAGGACACCAGTGATGCTCCTGGGACCCTACGCAATCTGCGCCTG
CGTCTCATCAGTCGCCCCACATGTAACTGTATCTACAACCAGCTGCACCAGCGACACCTGTCCA
ACCCGGCCCGGCCTGGGATGCTATGTGGGGGCCCCCAGCCTGGGGTGCAGGGCCCCTGTCAGGG
AGATTCCGGGGGCCCTGTGCTGTGCCTCGAGCCTGACGGACACTGGGTTCAGGCTGGCATCATC
AGCTTTGCATCAAGCTGTGCCCAGGAGGACGCTCCTGTGCTGCTGACCAACACAGCTGCTCACA
GTTCCTGGCTGCAGGCTCGAGTTCAGGGGGCAGCTTTCCTGGCCCAGAGCCCAGAGACCCCGGA
GATGAGTGATGAGGACAGCTGTGTAGCCTGTGGATCCTTGAGGACAGCAGGTCCCCAGGCAGGA
GCACCCTCCCCATGGCCCTGGGATGCCAGGCTGATGCACCAGGGACAGCTGGCCTGTGGCGGAG
CCCTGGTGTCAGAGGAGGCGGTGCTAACTGCTGCCCACTGCTTCATTGGGCGCCAGGCCCCAGA
GGAATGGAGCGTAGGGCTGGGGACCAGACCGGAGGAGTGGGGCCTGAAGCAGCTCATCCTGCAT
GGAGCCTACACCCACCCTGAGGGGGGCTACGACGTGGCCCTCCTGCTGCTGGCCCAGCCTGTGA
CACTGGGAGCCAGCCTGCGGCCCCTCTGCCTGCCCTATGCTGACCACCACCTGCCTGATGGGGA
GCGCGGCTGGGTTCTGGGACGGGCCCGCCCAGGAGCAGGCATCAGCTCCCTCCAGACAGTGCCC
GTGACCCTCCTGGGGCCTAGGGCCTGCAGCCGGCTGCATGCAGCTCCTGGGGGTGACGGCAGCC
CTATTCTGCCAGGGATGGTGTGTACCAGTGCTGTGGGTGAGCTGCCCAGCTGTGAGGGCCTGTC
TGGGGCACCACTGGTGCATGAGGTGAGGGGCACATGGTTCCTGGCCGGGCTGCACAGCTTCGGA
GATGCTTGCCAAGGCCCCGCCAGGCCGGCGGTCTTCACCGCGCTCCCTGCCTATGAGGACTGGG
TCAGCAGTTTGGACTGGCAGGTCTACTTCGCCGAGGAACCAGAGCCCGAGGCTGAGCCTGGAAG
CTGCCTGGCCAACATAAGCCAACCAACCAGCTGCTGACAGGGGACCTGGCCATTCTCAGGACAA
GAGAATGCAGGCAGGCAAATGGCATTACTGCCCCTGTCCTCCCCACCCTGTCATGTGTGATTCC
AGGCACCAGGGCAGGCCCAGAAGCCCAGCAGCTGTGGGAAGGAACCTGCCTGGGGCCACAGGTG
CCCACTCCCCACCCTGCAGGACAGGGGTGTTTGTGGACATTCCCACACCCAACTCTGCTACCAA
GCAGGTGTCCCAGCTTTCCTCCTCCTTTACCCTTTCAGATACAATCACGCCAGCCACGTTGTTT
TGAAAATTTCTTTTTTTGGGGGGCAGCAGTTTTCCTTTTTTAAACTTAAATAAATTGTTACAAA
ATAGACTTTA

hide sequence

RefSeq Acc Id:

XM_008959633 ⟹ XP_008957881

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	34,290,947 - 34,298,383 (-)	NCBI
NHGRI_mPanPan1	16	39,092,583 - 39,099,786 (-)	NCBI
Mhudiblu_PPA_v0	16	23,876,533 - 23,883,739 (+)	NCBI
PanPan1.1	16	31,452,188 - 31,459,549 (-)	NCBI

Sequence:

show sequence

ACCATGTGTCTGCCATGGACTGTGGTGCTGGGCCTCCCTCGGTGTTGCCTTCTCTGGAGCTGGG
AAGGGTCTTCAAGCCGCTCAGCGTGGTAAGGTCTGGGGACACGGGGCCTAGGTCTTACTTGGGT
CTGGGTTGGGACTGGGGTGAGGTCAGGACAGGTATCTGCTGTCAGTGTGACCAACTCCTTTCCA
CAGCCTGTGGACAGCGTGGCCCCGGCCCCCCCAAGCCTCAGGAGGGCAACACAGTCTCTGGCGA
GTGGCCCTGGCAGGCCAGTGTGAGGAGGCAAGGAGCCCACATCTGCAGCGGCTCCCTGGTGGCA
GACACCTGGGTCCTCACTGCTGCCCACTGCTTTGAAAAGGCAGCAGCAACAGAACTGAACTCCT
GGTCAGTGGTCCTGGGTTCTCTGCAGCGTGAGGGACTCAGCCCTGGGGCCGAAGAGGTGGGGGT
GGCTGCCCTGCAGTTGCCCAGGGCCTATAACCACTACAGCCAGGGCTCAGACCTGGCCCTGCTG
CAGCTCGCCCACCCCACGACCCACACACCCCTCTGCCTGCCCCAGCCTGTCCATCGCTTCCCCT
TTGGAGCCTCCTGCTGGGCCACTGGCTGGGATCAGGACACCAGTGATGGTAAGTGCTGGCCCAG
ACTGAAGCTCGGAGAGGCACTCTGCTTGCCCAGCGTCACAGTCTCAGCTCCCAACTGTCCTGGC
TTCCAGTCTCCCTTGCTTCCCAGATCCCAGACTCCAGCCCTAGCCCCGTCTCTTTCACCAGCTC
CTGGGACCCTACGCAATCTGCGCCTGCGTCTCATCAGTCGCCCCACATGTAACTGTATCTACAA
CCAGCTGCACCAGCGACACCTGTCCAACCCGGCCCGGCCTGGGATGCTATGTGGGGGCCCCCAG
CCTGGGGTGCAGGGCCCCTGTCAGGGAGATTCCGGGGGCCCTGTGCTGTGCCTCGAGCCTGACG
GACACTGGGTTCAGGCTGGCATCATCAGCTTTGCATCAAGCTGTGCCCAGGAGGACGCTCCTGT
GCTGCTGACCAACACAGCTGCTCACAGTTCCTGGCTGCAGGCTCGAGTTCAGGGGGCAGCTTTC
CTGGCCCAGAGCCCAGAGACCCCGGAGATGAGTGATGAGGACAGCTGTGTAGCCTGTGGATCCT
TGAGGACAGCAGGTCCCCAGGCAGGAGCACCCTCCCCATGGCCCTGGGATGCCAGGCTGATGCA
CCAGGGACAGCTGGCCTGTGGCGGAGCCCTGGTGTCAGAGGAGGCGGTGCTAACTGCTGCCCAC
TGCTTCATTGGGCGCCAGGCCCCAGAGGAATGGAGCGTAGGGCTGGGGACCAGACCGGAGGAGT
GGGGCCTGAAGCAGCTCATCCTGCATGGAGCCTACACCCACCCTGAGGGGGGCTACGACGTGGC
CCTCCTGCTGCTGGCCCAGCCTGTGACACTGGGAGCCAGCCTGCGGCCCCTCTGCCTGCCCTAT
GCTGACCACCACCTGCCTGATGGGGAGCGCGGCTGGGTTCTGGGACGGGCCCGCCCAGGAGCAG
GCATCAGCTCCCTCCAGACAGTGCCCGTGACCCTCCTGGGGCCTAGGGCCTGCAGCCGGCTGCA
TGCAGCTCCTGGGGGTGACGGCAGCCCTATTCTGCCAGGGATGGTGTGTACCAGTGCTGTGGGT
GAGCTGCCCAGCTGTGAGGGCCTGTCTGGGGCACCACTGGTGCATGAGGTGAGGGGCACATGGT
TCCTGGCCGGGCTGCACAGCTTCGGAGATGCTTGCCAAGGCCCCGCCAGGCCGGCGGTCTTCAC
CGCGCTCCCTGCCTATGAGGACTGGGTCAGCAGTTTGGACTGGCAGGTCTACTTCGCCGAGGAA
CCAGAGCCCGAGGCTGAGCCTGGAAGCTGCCTGGCCAACATAAGTATGTGGCCCCGGGGCCTCC
TGCCAAACCCTGCCTCTCCAGGACCCTTCTCTCTCCAGTGAGAACGTGCCGTTCTAACCCACTC
CAGCTGCCTTGGGTAGGGTGGAGCAACAGGCAGACCCATTTGATTCAGATTCTGGTTCTTTGTC
ATCGTGTGACTTGGAGCAGGCTGCTCAACAGCTTTGAGCCTCAGTATTCTCATCTGTCATGGCG
GCCAAGACAGACCCTGTTCCTTCGAGGAATGGGGAGGGAGGGAGGGACCAAAGCCGTGAGGATG
AGGACAACTCCACCCTCCTTCCTTCCCCACAGGCCAACCAACCAGCTGCTGACAGGGGACCTGG
CCATTCTCAGGACAAGAGAATGCAGGCAGGCAAATGGCATTACTGCCCCTGTCCTCCCCACCCT
GTCATGTGTGATTCCAGGCACCAGGGCAGGCCCAGAAGCCCAGCAGCTGTGGGAAGGAACCTGC
CTGGGGCCACAGGTGCCCACTCCCCACCCTGCAGGACAGGGGTGTTTGTGGACATTCCCACACC
CAACTCTGCTACCAAGCAGGTGTCCCAGCTTTCCTCCTCCTTTACCCTTTCAGATACAATCACG
CCAGCCACGTTGTTTTGAAAATTTCTTTTTTTGGGGGGCAGCAGTTTTCCTTTTTTAAACTTAA
ATAAATTGTTACAAAATAGA

hide sequence

RefSeq Acc Id:

XM_063597568 ⟹ XP_063453638

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	34,290,947 - 34,298,383 (-)	NCBI

RefSeq Acc Id:

XM_063597569 ⟹ XP_063453639

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	34,290,947 - 34,298,383 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003807540	(Get FASTA)	NCBI Sequence Viewer
	XP_008957881	(Get FASTA)	NCBI Sequence Viewer
	XP_063453638	(Get FASTA)	NCBI Sequence Viewer
	XP_063453639	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000039098
	ENSPPAP00000039098.1
	ENSPPAP00000039100.1

RefSeq Acc Id:	XP_003807540 ⟸ XM_003807492
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9CDN2 (UniProtKB/TrEMBL), A0A2R9CAX0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVSGEWPWQASVRRQGAHICSG SLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSD LALLQLAHPTTHTPLCLPQPVHRFPFGASCWATGWDQDTSDAPGTLRNLRLRLISRPTCNCIYN QLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPV LLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWDARLMH QGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDVA LLLLAQPVTLGASLRPLCLPYADHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLH AAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFT ALPAYEDWVSSLDWQVYFAEEPEPEAEPGSCLANISQPTSC hide sequence

RefSeq Acc Id:	XP_008957881 ⟸ XM_008959633
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CAX0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCGAGPPSVLPSLELGRVFKPLSVVRSGDTGPRSYLGLGWDWGEVRTGICCQCDQLLSTACGQ RGPGPPKPQEGNTVSGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVL GSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTPLCLPQPVHRFPFGASC WATGWDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQTPALAPSLSPAPGTLR NLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQ AGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAG PQAGAPSPWPWDARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQ LILHGAYTHPEGGYDVALLLLAQPVTLGASLRPLCLPYADHHLPDGERGWVLGRARPGAGISSL QTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGL HSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEPGSCLANISMWPRGLLPNPA SPGPFSLQ hide sequence

RefSeq Acc Id:

ENSPPAP00000039100 ⟸ ENSPPAT00000062009

RefSeq Acc Id:

ENSPPAP00000039098 ⟸ ENSPPAT00000062007

RefSeq Acc Id:	XP_063453639 ⟸ XM_063597569
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063453638 ⟸ XM_063597568
- Peptide Label:	isoform X1

Protein Domains

Peptidase S1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042266	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000062007.1	UniProtKB/TrEMBL
	ENSPPAT00000062009.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.10.10	UniProtKB/TrEMBL
InterPro	Peptidase_S1_PA	UniProtKB/TrEMBL
	Peptidase_S1_PA_chymotrypsin	UniProtKB/TrEMBL
	Peptidase_S1A	UniProtKB/TrEMBL
	Trypsin_dom	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
KEGG Report	pps:100989061	UniProtKB/TrEMBL
NCBI Gene	PRSS53	ENTREZGENE
PANTHER	POLYSERASE-2	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEASE SERINE	UniProtKB/TrEMBL
Pfam	Trypsin	UniProtKB/TrEMBL
PRINTS	CHYMOTRYPSIN	UniProtKB/TrEMBL
PROSITE	TRYPSIN_DOM	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
SMART	Tryp_SPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50494	UniProtKB/TrEMBL
UniProt	A0A2R9CAX0	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CDN2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-01-23	PRSS53	serine protease 53		protease, serine 53	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar