MTTP (microsomal triglyceride transfer protein) - Rat Genome Database

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Gene: MTTP (microsomal triglyceride transfer protein) Pan paniscus
Analyze
Symbol: MTTP
Name: microsomal triglyceride transfer protein
RGD ID: 11992948
Description: ENCODES a protein that exhibits apolipoprotein binding (ortholog); lipid transporter activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); establishment of localization in cell (ortholog); lipid metabolic process (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); abetalipoproteinemia (ortholog); Abetalipoproteinemia Neuropathy (ortholog); FOUND IN basolateral plasma membrane (ortholog); brush border membrane (ortholog); microvillus membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microsomal triglyceride transfer protein large subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,646,193 - 97,705,596 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,929,920 - 97,989,327 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,987,756 - 92,047,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,648,793 - 102,708,107 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,648,793 - 102,708,107 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MTTP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,646,193 - 97,705,596 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,929,920 - 97,989,327 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,987,756 - 92,047,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,648,793 - 102,708,107 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,648,793 - 102,708,107 (+)Ensemblpanpan1.1panPan2
MTTP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,564,130 - 99,623,997 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,564,081 - 99,623,997 (+)EnsemblGRCh38hg38GRCh38
GRCh374100,485,287 - 100,545,154 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,704,263 - 100,764,177 (+)NCBINCBI36Build 36hg18NCBI36
Build 344100,853,158 - 100,901,804NCBI
Celera497,782,659 - 97,842,577 (+)NCBICelera
Cytogenetic Map4q23NCBI
HuRef496,223,283 - 96,283,485 (+)NCBIHuRef
CHM1_14100,461,713 - 100,521,565 (+)NCBICHM1_1
T2T-CHM13v2.04102,878,899 - 102,939,426 (+)NCBIT2T-CHM13v2.0
Mttp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,795,616 - 137,849,179 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,795,615 - 137,850,729 (-)EnsemblGRCm39 Ensembl
GRCm383138,089,855 - 138,143,418 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,089,854 - 138,144,968 (-)EnsemblGRCm38mm10GRCm38
MGSCv373137,752,819 - 137,806,352 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,028,273 - 138,068,711 (-)NCBIMGSCv36mm8
Celera3144,502,913 - 144,554,347 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.06NCBI
Mttp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,286,501 - 229,327,650 (-)NCBIGRCr8
mRatBN7.22226,613,090 - 226,654,239 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,613,090 - 226,654,239 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,352,193 - 234,393,386 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,251,937 - 232,293,127 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,116,603 - 227,157,800 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,366,181 - 243,407,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,366,181 - 243,407,608 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,907,825 - 261,948,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,613,710 - 235,654,848 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,600,461 - 235,641,567 (-)NCBI
Celera2218,769,332 - 218,810,411 (-)NCBICelera
Cytogenetic Map2q43NCBI
Mttp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554967,963,262 - 8,009,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554967,963,323 - 8,022,393 (-)NCBIChiLan1.0ChiLan1.0
MTTP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,582,368 - 21,626,806 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3221,570,801 - 21,628,624 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3220,269,932 - 20,326,464 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03221,791,316 - 21,847,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3221,803,303 - 21,847,792 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13221,768,037 - 21,824,593 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,555,521 - 21,612,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,256,944 - 18,313,535 (-)NCBIUU_Cfam_GSD_1.0
Mttp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530119,994,708 - 20,057,294 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365203,338,881 - 3,381,627 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365203,337,726 - 3,417,818 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTTP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8120,820,656 - 120,879,388 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18120,820,660 - 120,871,468 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28130,036,478 - 130,087,445 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTTP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,706,591 - 47,765,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,717,089 - 47,765,149 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603726,182,236 - 26,230,115 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mttp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248307,464,686 - 7,506,129 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248307,463,671 - 7,505,607 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000053934   ⟹   ENSPPAP00000031070
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4102,648,793 - 102,708,107 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000053938   ⟹   ENSPPAP00000031074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4102,648,809 - 102,706,961 (+)Ensembl
RefSeq Acc Id: XM_034958944   ⟹   XP_034814835
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2397,646,193 - 97,705,596 (+)NCBI
NHGRI_mPanPan1497,929,920 - 97,989,327 (+)NCBI
Mhudiblu_PPA_v0491,987,756 - 92,047,127 (+)NCBI
RefSeq Acc Id: XM_055111660   ⟹   XP_054967635
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2397,652,620 - 97,705,596 (+)NCBI
NHGRI_mPanPan1497,936,351 - 97,989,327 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034814835 (Get FASTA)   NCBI Sequence Viewer  
  XP_054967635 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031070.1
  ENSPPAP00000031074.1
RefSeq Acc Id: XP_034814835   ⟸   XM_034958944
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BNW1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000031070   ⟸   ENSPPAT00000053934
Ensembl Acc Id: ENSPPAP00000031074   ⟸   ENSPPAT00000053938
RefSeq Acc Id: XP_054967635   ⟸   XM_055111660
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BN24 (UniProtKB/TrEMBL)
Protein Domains
Vitellogenin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038475 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053934.1 UniProtKB/TrEMBL
  ENSPPAT00000053938.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.20 UniProtKB/TrEMBL
InterPro Lipid_transp_b-sht_shell UniProtKB/TrEMBL
  Lipid_transpt_N UniProtKB/TrEMBL
  Lipovitellin_superhlx_dom UniProtKB/TrEMBL
  MTP_lip_bd UniProtKB/TrEMBL
  MTTP UniProtKB/TrEMBL
  Vitellinogen_b-sht_N UniProtKB/TrEMBL
NCBI Gene MTTP ENTREZGENE
PANTHER MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT UniProtKB/TrEMBL
  PTHR13024 UniProtKB/TrEMBL
Pfam MTP_lip_bd UniProtKB/TrEMBL
  Vitellogenin_N UniProtKB/TrEMBL
PROSITE VITELLOGENIN UniProtKB/TrEMBL
SMART LPD_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48431 UniProtKB/TrEMBL
UniProt A0A2R9BN24 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BNW1 ENTREZGENE, UniProtKB/TrEMBL