SLC26A5 (solute carrier family 26 member 5)

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Gene: SLC26A5 (solute carrier family 26 member 5) Pan paniscus

Analyze

Symbol:

SLC26A5

Name:

solute carrier family 26 member 5

RGD ID:

11992157

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); spectrin binding (ortholog); transcription factor binding (ortholog); INVOLVED IN anion transmembrane transport (ortholog); chloride transmembrane transport (ortholog); cochlea development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 61 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN basolateral plasma membrane (ortholog); cytoplasm (ortholog); lateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

prestin; solute carrier family 26, member 5 (prestin)

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	108,088,197 - 108,178,578 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	108,088,197 - 108,178,578 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	95,363,028 - 95,437,527 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive nonsyndromic deafness 61 (ISO)

Deafness (ISO)

Hearing Loss (ISO)

Hearing Loss, Noise-Induced (ISO)

hypothyroidism (ISO)

Nonsyndromic Sensorineural Hearing Loss (ISO)

pleomorphic xanthoastrocytoma (ISO)

Presbycusis (ISO)

sensorineural hearing loss (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anion transmembrane transport (ISO)

chloride transmembrane transport (ISO)

cochlea development (ISO)

fructose transmembrane transport (ISO)

ion transmembrane transport (ISO)

negative regulation of ion transmembrane transport (ISO)

positive regulation of cell motility (ISO)

positive regulation of cell size (ISO)

regulation of membrane potential (ISO)

response to auditory stimulus (ISO)

response to drug (ISO)

response to ischemia (ISO)

response to potassium ion (ISO)

response to salicylic acid (ISO)

response to salt (ISO)

response to thyroid hormone (ISO)

sensory perception of sound (ISO)

Cellular Component

basolateral plasma membrane (ISO)

cytoplasm (ISO)

lateral plasma membrane (ISO)

lateral wall of outer hair cell (ISO)

plasma membrane (ISO)

Molecular Function

identical protein binding (ISO)

protein binding (ISO)

spectrin binding (ISO)

transcription factor binding (ISO)

References

Genomics

Comparative Map Data

SLC26A5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	108,088,197 - 108,178,578 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	108,088,197 - 108,178,578 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	95,363,028 - 95,437,527 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

SLC26A5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	103,352,730 - 103,446,207 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	103,352,598 - 103,446,207 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	102,993,177 - 103,086,654 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	102,780,413 - 102,873,834 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	7	97,800,386 - 97,892,942 (-)	NCBI
Cytogenetic Map	7	q22.1	NCBI
HuRef	7	97,355,533 - 97,447,053 (-)	NCBI		HuRef
CHM1_1	7	102,926,169 - 103,019,937 (-)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	102,353,543 - 102,447,443 (-)	NCBI

Slc26a5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	22,013,999 - 22,070,602 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	22,015,653 - 22,070,602 (-)	Ensembl
GRCm38	5	21,809,001 - 21,865,604 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	21,810,655 - 21,865,604 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	21,316,473 - 21,371,422 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	21,322,479 - 21,377,428 (-)	NCBI			mm8
Celera	5	18,781,281 - 18,837,517 (-)	NCBI		Celera
Cytogenetic Map	5	A3	NCBI
cM Map	5	9.97	NCBI

Slc26a5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	13,210,260 - 13,249,289 (+)	NCBI
Rnor_6.0 Ensembl	4	9,821,541 - 9,860,571 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	9,795,811 - 9,860,904 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	9,822,682 - 9,861,708 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	8,657,314 - 8,697,539 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	8,657,313 - 8,697,539 (+)	NCBI
Celera	4	8,801,513 - 8,840,481 (+)	NCBI		Celera
Cytogenetic Map	4	q11	NCBI

Slc26a5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	8,358,786 - 8,414,145 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	8,358,780 - 8,414,145 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC26A5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	18	16,788,759 - 16,839,940 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	18	16,783,795 - 16,841,946 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Slc26a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936479	20,104,625 - 20,145,392 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC26A5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	103,378,776 - 103,453,730 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	103,382,558 - 103,420,054 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	113,990,590 - 114,062,746 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC26A5
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	72,347,276 - 72,418,311 (-)	NCBI
ChlSab1.1 Ensembl	21	72,347,792 - 72,393,765 (-)	Ensembl

Slc26a5
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624739	25,925,835 - 25,998,410 (+)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034964701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000064536 ⟹ ENSPPAP00000041610

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,088,197 - 108,178,578 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064538 ⟹ ENSPPAP00000041612

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,088,197 - 108,178,578 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064540 ⟹ ENSPPAP00000041614

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,088,197 - 108,178,578 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064544 ⟹ ENSPPAP00000041618

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,109,627 - 108,178,578 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064550 ⟹ ENSPPAP00000041624

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,109,627 - 108,178,578 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064558 ⟹ ENSPPAP00000041632

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,112,283 - 108,156,932 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064560 ⟹ ENSPPAP00000041634

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	108,124,359 - 108,156,932 (-)	Ensembl

RefSeq Acc Id:

XM_034964701 ⟹ XP_034820592

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
Mhudiblu_PPA_v0	7	95,363,028 - 95,437,527 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_034820592	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_034820592 ⟸ XM_034964701

RefSeq Acc Id:

ENSPPAP00000041612 ⟸ ENSPPAT00000064538

RefSeq Acc Id:

ENSPPAP00000041610 ⟸ ENSPPAT00000064536

RefSeq Acc Id:

ENSPPAP00000041624 ⟸ ENSPPAT00000064550

RefSeq Acc Id:

ENSPPAP00000041632 ⟸ ENSPPAT00000064558

RefSeq Acc Id:

ENSPPAP00000041614 ⟸ ENSPPAT00000064540

RefSeq Acc Id:

ENSPPAP00000041618 ⟸ ENSPPAT00000064544

RefSeq Acc Id:

ENSPPAP00000041634 ⟸ ENSPPAT00000064560

Protein Domains

STAS Sulfate_transp

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000043415	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000041610	UniProtKB/TrEMBL
	ENSPPAP00000041612	UniProtKB/TrEMBL
	ENSPPAP00000041614	UniProtKB/TrEMBL
	ENSPPAP00000041618	UniProtKB/TrEMBL
	ENSPPAP00000041624	UniProtKB/TrEMBL
	ENSPPAP00000041632	UniProtKB/TrEMBL
	ENSPPAP00000041634	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000064536	UniProtKB/TrEMBL
	ENSPPAT00000064538	UniProtKB/TrEMBL
	ENSPPAT00000064540	UniProtKB/TrEMBL
	ENSPPAT00000064544	UniProtKB/TrEMBL
	ENSPPAT00000064550	UniProtKB/TrEMBL
	ENSPPAT00000064558	UniProtKB/TrEMBL
	ENSPPAT00000064560	UniProtKB/TrEMBL
InterPro	Prestin	UniProtKB/TrEMBL
	S04_transporter_CS	UniProtKB/TrEMBL
	SLC26A/SulP_dom	UniProtKB/TrEMBL
	SLC26A/SulP_fam	UniProtKB/TrEMBL
	STAS_dom	UniProtKB/TrEMBL
	STAS_dom_sf	UniProtKB/TrEMBL
KEGG Report	pps:100985828	UniProtKB/TrEMBL
NCBI Gene	SLC26A5	ENTREZGENE
PANTHER	PTHR11814	UniProtKB/TrEMBL
	PTHR11814:SF32	UniProtKB/TrEMBL
Pfam	STAS	UniProtKB/TrEMBL
	Sulfate_transp	UniProtKB/TrEMBL
PROSITE	SLC26A	UniProtKB/TrEMBL
	STAS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52091	UniProtKB/TrEMBL
TIGRFAMs	sulP	UniProtKB/TrEMBL
UniProt	A0A2R9CI47_PANPA	UniProtKB/TrEMBL
	A0A2R9CI49_PANPA	UniProtKB/TrEMBL
	A0A2R9CI58_PANPA	UniProtKB/TrEMBL
	A0A2R9CI68_PANPA	UniProtKB/TrEMBL
	A0A2R9CKT3_PANPA	UniProtKB/TrEMBL
	A0A2R9CRI1_PANPA	UniProtKB/TrEMBL
	A0A2R9CRJ1_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM