PPEF1 (protein phosphatase with EF-hand domain 1) - Rat Genome Database

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Gene: PPEF1 (protein phosphatase with EF-hand domain 1) Pan paniscus
Analyze
Symbol: PPEF1
Name: protein phosphatase with EF-hand domain 1
RGD ID: 11991523
Description: ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); iron ion binding (inferred); INVOLVED IN detection of stimulus involved in sensory perception (inferred); ASSOCIATED WITH autistic disorder (ortholog); Coffin-Lowry syndrome (ortholog); developmental and epileptic encephalopathy 2 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein phosphatase with EF-hands 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X20,471,844 - 20,625,418 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X20,475,230 - 20,628,811 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X11,311,905 - 11,448,676 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X18,675,714 - 18,812,412 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX18,675,714 - 18,812,412 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PPEF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X20,471,844 - 20,625,418 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X20,475,230 - 20,628,811 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X11,311,905 - 11,448,676 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X18,675,714 - 18,812,412 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX18,675,714 - 18,812,412 (+)Ensemblpanpan1.1panPan2
PPEF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X18,675,067 - 18,827,917 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX18,675,909 - 18,827,921 (+)EnsemblGRCh38hg38GRCh38
GRCh37X18,693,187 - 18,846,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X18,618,966 - 18,755,956 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX22,829,137 - 22,966,124 (+)NCBICelera
Cytogenetic MapXp22.13NCBI
HuRefX16,462,688 - 16,598,790 (+)NCBIHuRef
CHM1_1X18,740,148 - 18,877,076 (+)NCBICHM1_1
T2T-CHM13v2.0X18,257,672 - 18,410,535 (+)NCBIT2T-CHM13v2.0
Ppef1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X159,404,997 - 159,534,286 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX159,406,090 - 159,518,761 (-)EnsemblGRCm39 Ensembl
GRCm38X160,622,419 - 160,751,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX160,623,094 - 160,735,765 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X157,061,026 - 157,157,904 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X155,967,609 - 156,038,528 (-)NCBIMGSCv36mm8
CeleraX143,864,055 - 143,960,973 (-)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX73.95NCBI
Ppef1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X37,803,204 - 37,960,378 (+)NCBIGRCr8
mRatBN7.2X33,994,503 - 34,151,704 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX34,021,350 - 34,151,701 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX35,194,826 - 35,309,125 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X38,656,656 - 38,770,959 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X36,331,981 - 36,446,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X35,822,687 - 35,947,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX35,869,538 - 35,947,282 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X36,142,176 - 36,270,449 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X55,347,219 - 55,436,212 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX34,715,653 - 34,830,012 (+)NCBICelera
Cytogenetic MapXq14NCBI
Ppef1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955586597,164 - 760,136 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955586597,620 - 761,433 (-)NCBIChiLan1.0ChiLan1.0
PPEF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X14,752,768 - 14,876,297 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX14,760,452 - 14,875,997 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X14,719,061 - 14,842,205 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX14,726,879 - 14,841,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X14,779,855 - 14,902,913 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X14,773,051 - 14,900,714 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X14,836,884 - 14,960,026 (+)NCBIUU_Cfam_GSD_1.0
Ppef1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X7,827,299 - 7,954,506 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936844318,367 - 445,183 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936844316,889 - 444,043 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPEF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX15,138,350 - 15,251,228 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X15,111,230 - 15,251,415 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X16,319,828 - 16,459,831 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPEF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X17,130,694 - 17,265,097 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX17,175,007 - 17,264,701 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605619,024,759 - 19,157,194 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppef1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248293,537,840 - 3,666,725 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248293,520,439 - 3,666,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000031965   ⟹   ENSPPAP00000009324
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX18,675,714 - 18,812,412 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000031972   ⟹   ENSPPAP00000009331
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX18,692,554 - 18,811,978 (+)Ensembl
RefSeq Acc Id: XM_055106111   ⟹   XP_054962086
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,471,937 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,323 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_055106112   ⟹   XP_054962087
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,471,937 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,323 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_055106113   ⟹   XP_054962088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,472,479 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,870 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_055106114   ⟹   XP_054962089
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,472,479 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,870 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_055106115   ⟹   XP_054962090
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,471,844 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,230 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_055106116   ⟹   XP_054962091
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,472,479 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,475,870 - 20,628,811 (+)NCBI
RefSeq Acc Id: XM_057301047   ⟹   XP_057157030
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X20,489,452 - 20,625,418 (+)NCBI
NHGRI_mPanPan1X20,492,848 - 20,628,811 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000009324   ⟸   ENSPPAT00000031965
RefSeq Acc Id: ENSPPAP00000009331   ⟸   ENSPPAT00000031972
RefSeq Acc Id: XP_054962090   ⟸   XM_055106115
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962087   ⟸   XM_055106112
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962086   ⟸   XM_055106111
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962089   ⟸   XM_055106114
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962088   ⟸   XM_055106113
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962091   ⟸   XM_055106116
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157030   ⟸   XM_057301047
- UniProtKB: A0A2R9A238 (UniProtKB/TrEMBL),   A0A2R8ZWI3 (UniProtKB/TrEMBL)
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027881 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031965.1 UniProtKB/TrEMBL
  ENSPPAT00000031972.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.21.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Calcineurin-like_PHP_ApaH UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/TrEMBL
  PPP_dom UniProtKB/TrEMBL
  Ser/Thr-Pase_EF-hand_contain UniProtKB/TrEMBL
  Ser/Thr-sp_prot-phosphatase UniProtKB/TrEMBL
KEGG Report pps:100981095 UniProtKB/TrEMBL
NCBI Gene PPEF1 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  Metallophos UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
  PPP5 UniProtKB/TrEMBL
PIRSF PPEF UniProtKB/TrEMBL
PRINTS STPHPHTASE UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SER_THR_PHOSPHATASE UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  PP2Ac UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF56300 UniProtKB/TrEMBL
UniProt A0A2R8ZWI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A238 ENTREZGENE, UniProtKB/TrEMBL