CNOT1 (CCR4-NOT transcription complex subunit 1) - Rat Genome Database

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Gene: CNOT1 (CCR4-NOT transcription complex subunit 1) Pan paniscus
Analyze
Symbol: CNOT1
Name: CCR4-NOT transcription complex subunit 1
RGD ID: 11987927
Description: ENCODES a protein that exhibits poly(A)-specific ribonuclease activity (ortholog); INVOLVED IN miRNA-mediated post-transcriptional gene silencing (inferred); negative regulation of intracellular estrogen receptor signaling pathway (inferred); negative regulation of retinoic acid receptor signaling pathway (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH alopecia-mental retardation syndrome 4 (ortholog); Bardet-Biedl syndrome (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN CCR4-NOT complex (inferred); CCR4-NOT core complex (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,919,276 - 58,027,472 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,919,283 - 58,027,472 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CNOT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,919,276 - 58,027,472 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,919,283 - 58,027,472 (-)Ensemblpanpan1.1panPan2
CNOT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,519,951 - 58,629,826 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,519,951 - 58,629,885 (-)EnsemblGRCh38hg38GRCh38
GRCh371658,553,855 - 58,663,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361657,111,356 - 57,221,251 (-)NCBINCBI36Build 36hg18NCBI36
Celera1643,052,843 - 43,163,048 (-)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1644,421,846 - 44,532,633 (-)NCBIHuRef
CHM1_11659,961,044 - 60,070,690 (-)NCBICHM1_1
T2T-CHM13v2.01664,315,184 - 64,422,344 (-)NCBIT2T-CHM13v2.0
Cnot1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39896,445,559 - 96,534,741 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl896,446,079 - 96,534,092 (-)EnsemblGRCm39 Ensembl
GRCm38895,718,931 - 95,808,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,719,451 - 95,807,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv37898,243,351 - 98,331,366 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36898,608,580 - 98,696,595 (-)NCBIMGSCv36mm8
Celera8100,030,369 - 100,118,172 (-)NCBICelera
Cytogenetic Map8D1NCBI
cM Map847.18NCBI
Cnot1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,261,290 - 9,352,636 (+)NCBIGRCr8
mRatBN7.2199,255,190 - 9,346,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,255,194 - 9,346,574 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,223,744 - 9,315,039 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,990,569 - 10,081,870 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,276,876 - 9,368,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,668,186 - 9,761,605 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,668,186 - 9,761,605 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,652,472 - 9,746,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,712,024 - 9,803,182 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,788,162 - 9,807,989 (+)NCBI
Celera199,151,859 - 9,241,563 (+)NCBICelera
Cytogenetic Map19p13NCBI
Cnot1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,938,791 - 16,027,545 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,938,791 - 16,027,547 (-)NCBIChiLan1.0ChiLan1.0
CNOT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,038,456 - 58,138,364 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,038,483 - 58,137,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,668,858 - 54,768,748 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0258,576,260 - 58,677,212 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,576,300 - 58,677,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1255,405,764 - 55,506,839 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0256,410,286 - 56,514,088 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,308,231 - 57,409,115 (+)NCBIUU_Cfam_GSD_1.0
Cnot1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,204,138 - 49,286,987 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647510,302,087 - 10,384,957 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647510,302,091 - 10,384,945 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl620,271,596 - 20,372,245 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1620,271,593 - 20,372,300 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2618,405,850 - 18,474,575 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1544,460,025 - 44,567,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl544,455,311 - 44,567,815 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604731,603,098 - 31,711,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474627,676,325 - 27,756,754 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474627,659,424 - 27,757,024 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000025018   ⟹   ENSPPAP00000005504
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1657,919,283 - 58,027,472 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000025076   ⟹   ENSPPAP00000005518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1657,920,276 - 57,998,296 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000025095   ⟹   ENSPPAP00000005526
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1657,920,276 - 57,998,296 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000025105   ⟹   ENSPPAP00000005532
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1657,975,291 - 57,998,296 (-)Ensembl
RefSeq Acc Id: XM_003823702   ⟹   XP_003823750
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,283 - 58,027,472 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008977353   ⟹   XP_008975601
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,276 - 58,027,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008977354   ⟹   XP_008975602
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,276 - 58,027,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008977355   ⟹   XP_008975603
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,276 - 58,027,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008977356   ⟹   XP_008975604
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,283 - 58,027,472 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024925887   ⟹   XP_024781655
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Mhudiblu_PPA_v01638,793,212 - 38,902,686 (-)NCBI
PanPan1.11657,919,276 - 58,027,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055099169   ⟹   XP_054955144
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,987,068 - 68,066,787 (-)NCBI
NHGRI_mPanPan11673,910,683 - 74,021,434 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008975604   ⟸   XM_008977356
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_003823750   ⟸   XM_003823702
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008975603   ⟸   XM_008977355
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008975602   ⟸   XM_008977354
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008975601   ⟸   XM_008977353
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024781655   ⟸   XM_024925887
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000005504   ⟸   ENSPPAT00000025018
RefSeq Acc Id: ENSPPAP00000005518   ⟸   ENSPPAT00000025076
RefSeq Acc Id: ENSPPAP00000005526   ⟸   ENSPPAT00000025095
RefSeq Acc Id: ENSPPAP00000005532   ⟸   ENSPPAT00000025105
RefSeq Acc Id: XP_054955144   ⟸   XM_055099169
- Peptide Label: isoform X7
Protein Domains
CCR4-Not complex component Not1 C-terminal   CCR4-NOT transcription complex subunit   CCR4-NOT transcription complex subunit 1 CAF1-   CCR4-NOT transcription complex subunit 1 HEAT   CCR4-NOT transcription complex subunit 1 TTP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000025018.1 UniProtKB/TrEMBL
  ENSPPAT00000025076.1 UniProtKB/TrEMBL
  ENSPPAT00000025095.1 UniProtKB/TrEMBL
  ENSPPAT00000025105.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.180 UniProtKB/TrEMBL
  1.25.40.790 UniProtKB/TrEMBL
  1.25.40.800 UniProtKB/TrEMBL
  1.25.40.840 UniProtKB/TrEMBL
InterPro CCR4-Not_Not1_C UniProtKB/TrEMBL
  CCR4-Not_Not1su_DUF3819 UniProtKB/TrEMBL
  CNOT1 UniProtKB/TrEMBL
  CNOT1_CAF1_bind UniProtKB/TrEMBL
  CNOT1_HEAT UniProtKB/TrEMBL
  CNOT1_TTP_bind UniProtKB/TrEMBL
  CNOT1_TTP_bind_sf UniProtKB/TrEMBL
KEGG Report pps:100993745 UniProtKB/TrEMBL
NCBI Gene CNOT1 ENTREZGENE
PANTHER CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 UniProtKB/TrEMBL
  PTHR13162 UniProtKB/TrEMBL
Pfam CNOT1_CAF1_bind UniProtKB/TrEMBL
  CNOT1_HEAT UniProtKB/TrEMBL
  CNOT1_TTP_bind UniProtKB/TrEMBL
  DUF3819 UniProtKB/TrEMBL
  Not1 UniProtKB/TrEMBL
UniProt A0A2R8ZKM3_PANPA UniProtKB/TrEMBL
  A0A2R8ZKN8_PANPA UniProtKB/TrEMBL
  A0A2R8ZLN5_PANPA UniProtKB/TrEMBL
  A0A2R8ZRR8_PANPA UniProtKB/TrEMBL