FRMD6 (FERM domain containing 6) - Rat Genome Database

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Gene: FRMD6 (FERM domain containing 6) Pan paniscus
Analyze
Symbol: FRMD6
Name: FERM domain containing 6
RGD ID: 11986172
Description: INVOLVED IN apical constriction (ortholog); protein localization (ortholog); regulation of actin filament-based process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN apical junction complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM domain-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21552,502,344 - 52,868,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11451,806,969 - 52,085,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01432,093,017 - 32,334,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11450,540,191 - 50,620,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1450,540,193 - 50,620,955 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FRMD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21552,502,344 - 52,868,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11451,806,969 - 52,085,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01432,093,017 - 32,334,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11450,540,191 - 50,620,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1450,540,193 - 50,620,955 (+)Ensemblpanpan1.1panPan2
FRMD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381451,396,431 - 51,730,727 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1451,489,100 - 51,730,727 (+)EnsemblGRCh38hg38GRCh38
GRCh371451,955,846 - 52,197,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,025,605 - 51,267,195 (+)NCBINCBI36Build 36hg18NCBI36
Build 341451,188,377 - 51,266,922NCBI
Celera1431,822,811 - 32,064,436 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1432,116,250 - 32,357,991 (+)NCBIHuRef
CHM1_11451,894,360 - 52,135,960 (+)NCBICHM1_1
T2T-CHM13v2.01445,603,294 - 45,937,636 (+)NCBIT2T-CHM13v2.0
Frmd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391270,872,235 - 70,949,009 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1270,872,288 - 70,949,008 (+)EnsemblGRCm39 Ensembl
GRCm381270,825,456 - 70,902,234 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,825,514 - 70,902,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv371271,926,501 - 72,003,221 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361271,744,119 - 71,820,839 (+)NCBIMGSCv36mm8
Celera1271,929,406 - 72,006,218 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.37NCBI
Frmd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,081,958 - 95,155,561 (+)NCBIGRCr8
mRatBN7.2689,345,983 - 89,419,579 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,346,035 - 89,419,579 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,730,030 - 89,803,595 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,029,493 - 90,103,062 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,469,004 - 89,542,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,281,382 - 93,358,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,281,408 - 93,358,840 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,731,955 - 102,804,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,953,340 - 93,027,451 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1692,994,730 - 93,018,418 (+)NCBI
Celera687,828,524 - 87,901,645 (+)NCBICelera
Cytogenetic Map6q24NCBI
Frmd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540911,262,204 - 11,302,146 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540911,262,456 - 11,420,892 (-)NCBIChiLan1.0ChiLan1.0
FRMD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1827,757,320 - 27,989,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl827,952,398 - 27,987,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha827,509,615 - 27,742,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0827,934,649 - 28,166,956 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl828,092,880 - 28,166,956 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1827,604,816 - 27,836,513 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0827,664,576 - 27,897,009 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0828,012,258 - 28,244,423 (+)NCBIUU_Cfam_GSD_1.0
Frmd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864060,130,802 - 60,221,267 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649513,970,408 - 14,061,010 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649513,969,753 - 14,060,946 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1181,338,525 - 181,416,840 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11181,338,404 - 181,416,813 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21201,656,066 - 201,698,230 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FRMD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,768,362 - 28,849,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2428,808,551 - 28,849,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605316,905,156 - 17,153,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473117,282,088 - 17,359,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473117,284,024 - 17,380,406 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058318   ⟹   ENSPPAP00000035430
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1450,540,193 - 50,620,955 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000058321   ⟹   ENSPPAP00000035433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1450,541,755 - 50,620,955 (+)Ensembl
RefSeq Acc Id: XM_003831718   ⟹   XP_003831766
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,593 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,097 - 52,085,426 (+)NCBI
Mhudiblu_PPA_v01432,255,379 - 32,334,665 (+)NCBI
PanPan1.11450,541,755 - 50,620,955 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003831719   ⟹   XP_003831767
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,598 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,102 - 52,085,426 (+)NCBI
Mhudiblu_PPA_v01432,255,388 - 32,334,665 (+)NCBI
PanPan1.11450,541,755 - 50,620,955 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957074   ⟹   XP_008955322
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,734 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,315 - 52,085,426 (+)NCBI
Mhudiblu_PPA_v01432,255,715 - 32,334,665 (+)NCBI
PanPan1.11450,541,970 - 50,620,955 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034937550   ⟹   XP_034793441
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,790,405 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,526 - 52,085,426 (+)NCBI
Mhudiblu_PPA_v01432,256,291 - 32,334,665 (+)NCBI
RefSeq Acc Id: XM_055097577   ⟹   XP_054953552
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,605 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,109 - 52,085,426 (+)NCBI
RefSeq Acc Id: XM_055097578   ⟹   XP_054953553
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,590,647 - 52,868,917 (+)NCBI
NHGRI_mPanPan11451,806,969 - 52,085,426 (+)NCBI
RefSeq Acc Id: XM_055097580   ⟹   XP_054953555
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,600 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,104 - 52,085,426 (+)NCBI
RefSeq Acc Id: XM_055097581   ⟹   XP_054953556
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,790,132 - 52,868,917 (+)NCBI
NHGRI_mPanPan11452,006,527 - 52,085,426 (+)NCBI
RefSeq Acc Id: XM_063596208   ⟹   XP_063452278
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,502,344 - 52,868,917 (+)NCBI
RefSeq Acc Id: XM_063596209   ⟹   XP_063452279
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21552,789,734 - 52,868,917 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003831767   ⟸   XM_003831719
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003831766   ⟸   XM_003831718
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C0H5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008955322   ⟸   XM_008957074
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034793441   ⟸   XM_034937550
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000035430   ⟸   ENSPPAT00000058318
RefSeq Acc Id: ENSPPAP00000035433   ⟸   ENSPPAT00000058321
RefSeq Acc Id: XP_054953553   ⟸   XM_055097578
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953555   ⟸   XM_055097580
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C0H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953552   ⟸   XM_055097577
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953556   ⟸   XM_055097581
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C0H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452278   ⟸   XM_063596208
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C3L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452279   ⟸   XM_063596209
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C0H5 (UniProtKB/TrEMBL)
Protein Domains
FERM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040522 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058318.1 UniProtKB/TrEMBL
  ENSPPAT00000058321.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  FRMD6-FERM_C UniProtKB/TrEMBL
  FRMD6-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report pps:100971681 UniProtKB/TrEMBL
NCBI Gene FRMD6 ENTREZGENE
PANTHER FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY UniProtKB/TrEMBL
  FERM DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
Pfam FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A2R9C0H5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C3L7 ENTREZGENE, UniProtKB/TrEMBL