GFM2 (GTP dependent ribosome recycling factor mitochondrial 2) - Rat Genome Database

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Gene: GFM2 (GTP dependent ribosome recycling factor mitochondrial 2) Pan paniscus
Analyze
Symbol: GFM2
Name: GTP dependent ribosome recycling factor mitochondrial 2
RGD ID: 11984422
Description: ENCODES a protein that exhibits translation elongation factor activity (ortholog); INVOLVED IN mitochondrial translational elongation (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 1 (ortholog); combined oxidative phosphorylation deficiency 39 (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G elongation factor mitochondrial 2; ribosome-releasing factor 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,544,985 - 40,590,872 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,698,620 - 38,744,507 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,543,368 - 40,589,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1541,153,714 - 41,199,765 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,153,714 - 41,204,297 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
mitochondrion  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GFM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,544,985 - 40,590,872 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,698,620 - 38,744,507 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,543,368 - 40,589,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1541,153,714 - 41,199,765 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,153,714 - 41,204,297 (+)Ensemblpanpan1.1panPan2
GFM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38574,721,206 - 74,767,117 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl574,721,206 - 74,767,147 (-)EnsemblGRCh38hg38GRCh38
GRCh37574,017,031 - 74,062,942 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,052,787 - 74,098,798 (-)NCBINCBI36Build 36hg18NCBI36
Celera569,911,787 - 69,957,794 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,221,970 - 69,268,174 (-)NCBIHuRef
CHM1_1573,449,890 - 73,496,044 (-)NCBICHM1_1
T2T-CHM13v2.0575,202,108 - 75,248,032 (-)NCBIT2T-CHM13v2.0
Gfm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,274,445 - 97,317,710 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1397,274,445 - 97,317,703 (+)EnsemblGRCm39 Ensembl
GRCm381397,137,933 - 97,181,202 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,137,937 - 97,181,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv371397,907,892 - 97,951,151 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361398,238,739 - 98,277,150 (+)NCBIMGSCv36mm8
Celera13100,771,320 - 100,814,229 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
Gfm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8230,184,063 - 30,222,811 (+)NCBIGRCr8
mRatBN7.2228,449,452 - 28,488,200 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx235,503,371 - 35,538,042 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0233,597,709 - 33,632,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0228,411,454 - 28,446,117 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0227,949,195 - 27,984,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,949,208 - 27,984,256 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0247,060,093 - 47,094,934 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,618,278 - 27,649,505 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1227,538,637 - 27,568,922 (+)NCBI
Celera224,491,429 - 24,526,041 (+)NCBICelera
Cytogenetic Map2q12NCBI
Gfm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,904,020 - 25,942,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,904,020 - 25,942,384 (+)NCBIChiLan1.0ChiLan1.0
GFM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,248,610 - 57,304,148 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,248,610 - 57,304,102 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,228,827 - 54,290,619 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0257,775,262 - 57,837,411 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl257,775,268 - 57,837,358 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1254,839,331 - 54,901,649 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0255,602,440 - 55,664,498 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0256,499,647 - 56,561,816 (-)NCBIUU_Cfam_GSD_1.0
Gfm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,940,289 - 188,985,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365491,873,694 - 1,918,221 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365491,873,700 - 1,918,371 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,779,439 - 83,843,839 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,770,518 - 83,843,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,358,245 - 85,429,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GFM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,065,841 - 69,114,724 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl469,066,293 - 69,114,508 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604917,843,732 - 17,892,518 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624924148,836 - 195,123 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624924142,424 - 195,426 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000049358   ⟹   ENSPPAP00000026525
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl541,153,714 - 41,199,765 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000049376   ⟹   ENSPPAP00000026542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl541,157,246 - 41,204,297 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000049384   ⟹   ENSPPAP00000026550
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl541,157,246 - 41,204,297 (+)Ensembl
RefSeq Acc Id: XM_003810463   ⟹   XP_003810511
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2440,544,985 - 40,590,872 (+)NCBI
NHGRI_mPanPan1538,698,620 - 38,744,507 (+)NCBI
Mhudiblu_PPA_v0540,543,368 - 40,589,478 (+)NCBI
PanPan1.1541,153,714 - 41,199,765 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003810511 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000026525
  ENSPPAP00000026525.1
  ENSPPAP00000026542.1
  ENSPPAP00000026550.1
Reference Protein Sequences
RefSeq Acc Id: XP_003810511   ⟸   XM_003810463
- UniProtKB: A0A2R9BBQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000026542   ⟸   ENSPPAT00000049376
RefSeq Acc Id: ENSPPAP00000026550   ⟸   ENSPPAT00000049384
RefSeq Acc Id: ENSPPAP00000026525   ⟸   ENSPPAT00000049358
Protein Domains
tr-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036359 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049358.1 UniProtKB/TrEMBL
  ENSPPAT00000049376.1 UniProtKB/TrEMBL
  ENSPPAT00000049384.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.230.10 UniProtKB/TrEMBL
  3.30.70.240 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Elongation Factor G (Translational Gtpase), domain 3 UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro EFG2 UniProtKB/TrEMBL
  EFG_II UniProtKB/TrEMBL
  EFG_III UniProtKB/TrEMBL
  EFG_III/V UniProtKB/TrEMBL
  EFG_V UniProtKB/TrEMBL
  EFG_V-like UniProtKB/TrEMBL
  EFTu-like_2 UniProtKB/TrEMBL
  G_TR_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
  Transl_elong_EFG/EF2_IV UniProtKB/TrEMBL
KEGG Report pps:100991789 UniProtKB/TrEMBL
NCBI Gene GFM2 ENTREZGENE
PANTHER RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL UniProtKB/TrEMBL
  TRANSLATION ELONGATION FACTOR G-RELATED UniProtKB/TrEMBL
Pfam EFG_C UniProtKB/TrEMBL
  EFG_III UniProtKB/TrEMBL
  EFG_IV UniProtKB/TrEMBL
  GTP_EFTU UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/TrEMBL
PRINTS ELONGATNFCT UniProtKB/TrEMBL
PROSITE G_TR_1 UniProtKB/TrEMBL
  G_TR_2 UniProtKB/TrEMBL
SMART EFG_C UniProtKB/TrEMBL
  EFG_IV UniProtKB/TrEMBL
Superfamily-SCOP SSF50447 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF54211 UniProtKB/TrEMBL
  SSF54980 UniProtKB/TrEMBL
UniProt A0A2R9BBQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BI30_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-14 GFM2  GTP dependent ribosome recycling factor mitochondrial 2  GFM2  G elongation factor mitochondrial 2  Symbol and/or name change 5135510 APPROVED