PRMT6 (protein arginine methyltransferase 6) - Rat Genome Database

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Gene: PRMT6 (protein arginine methyltransferase 6) Pan paniscus
Analyze
Symbol: PRMT6
Name: protein arginine methyltransferase 6
RGD ID: 11982209
Description: ENCODES a protein that exhibits histone H3 methyltransferase activity (ortholog); INVOLVED IN cellular senescence (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of signal transduction by p53 class mediator (ortholog); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Cocaine-Related Disorders (ortholog); genetic disease (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21120,092,339 - 120,101,205 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11119,254,648 - 119,262,030 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01109,582,715 - 109,586,744 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11108,698,959 - 108,701,675 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1108,699,098 - 108,700,225 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRMT6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21120,092,339 - 120,101,205 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11119,254,648 - 119,262,030 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01109,582,715 - 109,586,744 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11108,698,959 - 108,701,675 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1108,699,098 - 108,700,225 (+)Ensemblpanpan1.1panPan2
PRMT6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381107,056,674 - 107,059,294 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1107,056,674 - 107,067,636 (+)EnsemblGRCh38hg38GRCh38
GRCh371107,599,296 - 107,601,916 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361107,400,932 - 107,403,437 (+)NCBINCBI36Build 36hg18NCBI36
Build 341107,311,450 - 107,313,956NCBI
Celera1105,773,915 - 105,776,564 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1105,545,085 - 105,547,734 (+)NCBIHuRef
CHM1_11107,714,159 - 107,716,808 (+)NCBICHM1_1
T2T-CHM13v2.01107,094,127 - 107,096,747 (+)NCBIT2T-CHM13v2.0
Prmt6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393110,153,420 - 110,158,315 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3110,153,425 - 110,158,314 (-)EnsemblGRCm39 Ensembl
GRCm383110,246,104 - 110,250,999 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3110,246,109 - 110,250,998 (-)EnsemblGRCm38mm10GRCm38
MGSCv373110,049,027 - 110,053,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363110,374,165 - 110,379,032 (-)NCBIMGSCv36mm8
Celera3112,566,108 - 112,570,997 (-)NCBICelera
Cytogenetic Map3F3NCBI
cM Map348.52NCBI
Prmt6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82200,615,780 - 200,620,790 (-)NCBIGRCr8
mRatBN7.22197,927,750 - 197,932,760 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2197,927,220 - 197,933,648 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2205,562,575 - 205,567,585 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02203,446,769 - 203,451,779 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02198,263,856 - 198,268,866 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02213,173,403 - 213,180,721 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2213,173,403 - 213,178,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2213,420,314 - 213,421,811 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02232,884,952 - 232,891,997 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42205,909,919 - 205,915,148 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2190,562,721 - 190,567,950 (-)NCBICelera
Cytogenetic Map2q41NCBI
Prmt6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543510,816,831 - 10,817,961 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543510,816,787 - 10,818,047 (+)NCBIChiLan1.0ChiLan1.0
PRMT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1644,475,829 - 44,478,215 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl644,477,030 - 44,478,160 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha647,259,804 - 47,262,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0644,760,879 - 44,763,512 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl644,762,342 - 44,763,472 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1644,493,521 - 44,496,159 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0644,456,290 - 44,458,926 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0644,890,485 - 44,893,116 (-)NCBIUU_Cfam_GSD_1.0
Prmt6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058116,310,340 - 116,320,458 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367311,266,738 - 1,267,865 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367311,262,335 - 1,268,200 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRMT6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4112,701,088 - 112,703,581 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14112,698,865 - 112,710,305 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24123,465,576 - 123,467,796 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRMT6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12026,547,305 - 26,551,327 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2026,550,130 - 26,551,257 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603831,689,660 - 31,693,631 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prmt6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247723,071,844 - 3,075,601 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247723,071,601 - 3,075,866 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003822230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000014814   ⟹   ENSPPAP00000003199
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1108,699,098 - 108,700,225 (+)Ensembl
RefSeq Acc Id: XM_003822230   ⟹   XP_003822278
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21120,092,339 - 120,101,205 (-)NCBI
NHGRI_mPanPan11119,254,648 - 119,262,030 (-)NCBI
Mhudiblu_PPA_v01109,582,715 - 109,586,744 (+)NCBI
PanPan1.11108,698,959 - 108,701,675 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003822278 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003199
  ENSPPAP00000003199.1
Reference Protein Sequences
RefSeq Acc Id: XP_003822278   ⟸   XM_003822230
- UniProtKB: A0A2R8ZHG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000003199   ⟸   ENSPPAT00000014814
Protein Domains
Methyltransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000013532 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000014814.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  Hnrnp arginine n-methyltransferase1 UniProtKB/TrEMBL
InterPro Arg_MeTrfase UniProtKB/TrEMBL
  Methyltransf_25 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report pps:100988055 UniProtKB/TrEMBL
NCBI Gene PRMT6 ENTREZGENE
PANTHER PROTEIN ARGININE N-METHYLTRANSFERASE 6 UniProtKB/TrEMBL
  PTHR11006 UniProtKB/TrEMBL
Pfam Methyltransf_25 UniProtKB/TrEMBL
PROSITE SAM_MT_PRMT UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A2R8ZHG6 ENTREZGENE, UniProtKB/TrEMBL