DYNLL1 (dynein light chain LC8-type 1) - Rat Genome Database

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Gene: DYNLL1 (dynein light chain LC8-type 1) Pan paniscus
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Symbol: DYNLL1
Name: dynein light chain LC8-type 1
RGD ID: 11978285
Description: ENCODES a protein that exhibits deoxyribonuclease inhibitor activity (ortholog); enzyme binding (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN intraciliary retrograde transport (ortholog); mitocytosis (ortholog); motile cilium assembly (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH brain ischemia (ortholog); cardiac arrest (ortholog); congestive heart failure (ortholog); FOUND IN axon cytoplasm (ortholog); COP9 signalosome (ortholog); cytoplasmic dynein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein light chain 1, cytoplasmic; LOC117975226; uncharacterized LOC117975226
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,539,098 - 128,567,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,535,475 - 128,563,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,078,401 - 118,080,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,452,118 - 121,454,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,452,118 - 121,454,550 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DYNLL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,539,098 - 128,567,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,535,475 - 128,563,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,078,401 - 118,080,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,452,118 - 121,454,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,452,118 - 121,454,550 (+)Ensemblpanpan1.1panPan2
DYNLL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,469,842 - 120,498,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,469,850 - 120,498,493 (+)EnsemblGRCh38hg38GRCh38
GRCh3712120,907,645 - 120,936,296 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,392,043 - 119,420,681 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412119,396,652 - 119,399,010NCBI
Celera12120,542,375 - 120,570,391 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12117,917,550 - 117,946,088 (+)NCBIHuRef
CHM1_112120,876,465 - 120,905,100 (+)NCBICHM1_1
T2T-CHM13v2.012120,459,024 - 120,487,665 (+)NCBIT2T-CHM13v2.0
Dynll1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,435,129 - 115,438,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,435,169 - 115,439,058 (-)EnsemblGRCm39 Ensembl
GRCm385115,297,110 - 115,300,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,297,110 - 115,300,999 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,747,119 - 115,750,999 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,559,422 - 115,561,933 (-)NCBIMGSCv36mm8
Celera5112,394,410 - 112,398,301 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.04NCBI
Dynll1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,945,291 - 46,976,867 (+)NCBIGRCr8
mRatBN7.21241,312,365 - 41,316,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,312,367 - 41,314,741 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,479,075 - 42,481,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,092,738 - 43,095,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,153,290 - 42,155,661 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,074,200 - 47,076,573 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,074,200 - 47,076,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,867,516 - 48,869,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,580,542 - 42,582,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,443,929 - 42,446,302 (+)NCBI
Celera1242,933,102 - 42,935,475 (+)NCBICelera
Cytogenetic Map12q16NCBI
Dynll1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545511,148,047 - 11,150,859 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545511,148,041 - 11,150,860 (-)NCBIChiLan1.0ChiLan1.0
DYNLL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,369,878 - 16,402,302 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,398,886 - 16,402,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,399,889 - 16,402,458 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,373,479 - 16,405,461 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,637,042 - 16,669,452 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,667,035 - 16,670,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,597,102 - 16,629,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,673,811 - 16,705,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,715,648 - 16,747,621 (+)NCBIUU_Cfam_GSD_1.0
Dynll1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,952,956 - 145,985,917 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668448,489 - 500,800 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668451,846 - 484,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,455,985 - 40,459,104 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,455,954 - 40,458,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21442,956,562 - 42,958,960 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,851,020 - 115,855,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11115,851,381 - 115,851,647 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,247,006 - 129,249,444 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynll1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474713,169,865 - 13,172,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474713,169,865 - 13,172,592 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000048125   ⟹   ENSPPAP00000025298
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12121,452,118 - 121,454,550 (+)Ensembl
RefSeq Acc Id: XM_055096255   ⟹   XP_054952230
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210128,539,098 - 128,567,509 (+)NCBI
NHGRI_mPanPan112128,535,475 - 128,563,886 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054952230 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025298.1
RefSeq Acc Id: ENSPPAP00000025298   ⟸   ENSPPAT00000048125
RefSeq Acc Id: XP_054952230   ⟸   XM_055096255
- UniProtKB: A0A2R9B6T4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048125.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.740.10 UniProtKB/TrEMBL
InterPro DLC_sf UniProtKB/TrEMBL
  Dynein_light_1/2_CS UniProtKB/TrEMBL
  Dynein_light_chain_typ-1/2 UniProtKB/TrEMBL
KEGG Report pps:100969037 UniProtKB/TrEMBL
NCBI Gene DYNLL1 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN 1, CYTOPLASMIC UniProtKB/TrEMBL
  PTHR11886 UniProtKB/TrEMBL
Pfam Dynein_light UniProtKB/TrEMBL
PROSITE DYNEIN_LIGHT_1 UniProtKB/TrEMBL
SMART Dynein_light UniProtKB/TrEMBL
Superfamily-SCOP SSF54648 UniProtKB/TrEMBL
UniProt A0A2R9B6T4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 DYNLL1  dynein light chain LC8-type 1  LOC117975226  uncharacterized LOC117975226  Data merged from RGD:32728103 737654 PROVISIONAL