BCO1 (beta-carotene oxygenase 1) - Rat Genome Database

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Gene: BCO1 (beta-carotene oxygenase 1) Pan paniscus
Analyze
Symbol: BCO1
Name: beta-carotene oxygenase 1
RGD ID: 11975342
Description: ENCODES a protein that exhibits beta-carotene 15,15'-dioxygenase activity (ortholog); INVOLVED IN beta-carotene metabolic process (ortholog); retinal metabolic process (ortholog); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH genetic disease (ortholog); giant axonal neuropathy 1 (ortholog); Hypercarotenemia and Vitamin A Deficiency, Autosomal Dominant (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BCMO1; beta,beta-carotene 15,15'-dioxygenase; beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21890,987,587 - 91,047,027 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,908,478 - 96,962,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,843,567 - 61,897,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11681,270,957 - 81,323,088 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,270,577 - 81,323,088 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
BCO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21890,987,587 - 91,047,027 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,908,478 - 96,962,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,843,567 - 61,897,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11681,270,957 - 81,323,088 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,270,577 - 81,323,088 (+)Ensemblpanpan1.1panPan2
BCO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381681,238,689 - 81,291,142 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1681,238,689 - 81,291,142 (+)EnsemblGRCh38hg38GRCh38
GRCh371681,272,294 - 81,324,747 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361679,829,797 - 79,882,248 (+)NCBINCBI36Build 36hg18NCBI36
Build 341679,829,796 - 79,882,248NCBI
Celera1665,569,740 - 65,622,032 (+)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1667,027,575 - 67,079,925 (+)NCBIHuRef
CHM1_11682,683,655 - 82,736,052 (+)NCBICHM1_1
T2T-CHM13v2.01687,299,473 - 87,351,905 (+)NCBIT2T-CHM13v2.0
Bco1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398117,822,590 - 117,860,459 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8117,822,593 - 117,860,459 (+)EnsemblGRCm39 Ensembl
GRCm388117,095,851 - 117,133,720 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8117,095,854 - 117,133,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv378119,619,765 - 119,657,620 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368119,981,842 - 120,019,458 (+)NCBIMGSCv36mm8
Celera8121,315,369 - 121,353,295 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map863.61NCBI
Bco1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81962,058,061 - 62,094,923 (+)NCBIGRCr8
mRatBN7.21945,149,250 - 45,186,102 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1945,149,265 - 45,186,101 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1951,959,095 - 51,995,942 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01952,612,116 - 52,648,960 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,856,354 - 54,893,189 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,637,059 - 49,673,577 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,637,016 - 49,673,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,424,580 - 60,460,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,202,955 - 47,239,225 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11947,207,835 - 47,244,106 (+)NCBI
Celera1944,421,345 - 44,457,802 (+)NCBICelera
Cytogenetic Map19q12NCBI
Bco1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555223,985,266 - 4,018,886 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555223,985,515 - 4,018,116 (+)NCBIChiLan1.0ChiLan1.0
BCO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1570,598,743 - 70,637,273 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl570,599,284 - 70,637,017 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha570,547,948 - 70,586,427 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0570,903,713 - 70,942,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl570,903,715 - 70,942,392 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1570,846,152 - 70,884,642 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0570,681,343 - 70,719,822 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,159,198 - 71,197,682 (-)NCBIUU_Cfam_GSD_1.0
Bco1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934930,698,707 - 30,729,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647528,859,318 - 28,889,934 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647528,859,222 - 28,890,407 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl67,012,332 - 7,055,305 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.167,008,330 - 7,054,089 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BCO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1566,681,756 - 66,730,832 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl566,681,513 - 66,733,604 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660479,105,596 - 9,155,354 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bco1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,143,892 - 6,180,408 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,146,338 - 6,181,020 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000015132   ⟹   ENSPPAP00000003281
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1681,270,577 - 81,323,088 (+)Ensembl
RefSeq Acc Id: XM_003820890   ⟹   XP_003820938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21890,987,587 - 91,047,027 (+)NCBI
NHGRI_mPanPan11696,908,478 - 96,962,121 (+)NCBI
Mhudiblu_PPA_v01661,843,568 - 61,897,012 (+)NCBI
PanPan1.11681,270,957 - 81,323,088 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820938 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003281.1
RefSeq Acc Id: XP_003820938   ⟸   XM_003820890
- Sequence:
RefSeq Acc Id: ENSPPAP00000003281   ⟸   ENSPPAT00000015132


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000013810 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015132.1 UniProtKB/TrEMBL
InterPro Carotenoid_Oase UniProtKB/TrEMBL
KEGG Report pps:100987572 UniProtKB/TrEMBL
NCBI Gene BCO1 ENTREZGENE
PANTHER BETA,BETA-CAROTENE 15,15'-DIOXYGENASE UniProtKB/TrEMBL
  PTHR10543 UniProtKB/TrEMBL
Pfam RPE65 UniProtKB/TrEMBL
UniProt A0A2R8ZE23_PANPA UniProtKB/TrEMBL