FXYD5 (FXYD domain containing ion transport regulator 5) - Rat Genome Database

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Gene: FXYD5 (FXYD domain containing ion transport regulator 5) Pan paniscus
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Symbol: FXYD5
Name: FXYD domain containing ion transport regulator 5
RGD ID: 11971121
Description: ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN monoatomic ion transport (inferred); regulation of monoatomic ion transport (inferred); ASSOCIATED WITH Brugada syndrome 5 (ortholog); dystonia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FXYD domain-containing ion transport regulator 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,166,684 - 41,182,021 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,150,032 - 43,165,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,100,475 - 32,115,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,838,920 - 40,854,027 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,839,798 - 40,854,027 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FXYD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,166,684 - 41,182,021 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,150,032 - 43,165,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,100,475 - 32,115,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,838,920 - 40,854,027 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,839,798 - 40,854,027 (+)Ensemblpanpan1.1panPan2
FXYD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,154,735 - 35,169,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,154,730 - 35,169,881 (+)EnsemblGRCh38hg38GRCh38
GRCh371935,645,638 - 35,660,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,337,467 - 40,352,625 (+)NCBINCBI36Build 36hg18NCBI36
Celera1932,359,062 - 32,374,225 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,154,002 - 32,169,298 (+)NCBIHuRef
CHM1_11935,647,512 - 35,662,675 (+)NCBICHM1_1
T2T-CHM13v2.01937,699,360 - 37,714,531 (+)NCBIT2T-CHM13v2.0
Fxyd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,732,153 - 30,741,565 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,732,147 - 30,741,906 (-)EnsemblGRCm39 Ensembl
GRCm38731,032,723 - 31,042,331 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl731,032,722 - 31,042,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,817,742 - 31,827,341 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,741,498 - 30,750,894 (-)NCBIMGSCv36mm8
Celera725,600,304 - 25,609,849 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.29NCBI
Fxyd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,395,327 - 95,404,722 (-)NCBIGRCr8
mRatBN7.2186,267,937 - 86,277,329 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,267,406 - 86,277,519 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,688,184 - 91,697,726 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,154,329 - 100,163,871 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,446,461 - 93,456,003 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,464,853 - 89,474,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,464,860 - 89,474,252 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,620,335 - 90,629,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,076,279 - 86,085,681 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,154,389 - 86,163,792 (-)NCBI
Celera180,636,897 - 80,646,373 (-)NCBICelera
Cytogenetic Map1q21NCBI
Fxyd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554684,470,148 - 4,480,386 (+)NCBIChiLan1.0ChiLan1.0
FXYD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,412,878 - 117,424,052 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,219,880 - 117,423,703 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,815,681 - 116,827,381 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,012,584 - 118,024,310 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11117,575,239 - 117,586,935 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,200,574 - 117,212,269 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,257,017 - 118,268,732 (-)NCBIUU_Cfam_GSD_1.0
Fxyd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,540,962 - 10,550,554 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365701,095,373 - 1,104,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FXYD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1644,682,245 - 44,696,088 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,131,800 - 40,145,611 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FXYD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,087,554 - 30,103,360 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,087,558 - 30,104,530 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660737,860,898 - 7,876,716 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fxyd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247948,347,925 - 8,359,215 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000057995   ⟹   ENSPPAP00000035109
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1940,839,798 - 40,854,027 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057999   ⟹   ENSPPAP00000035113
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1940,839,798 - 40,843,855 (+)Ensembl
RefSeq Acc Id: XM_003816122   ⟹   XP_003816170
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22041,166,684 - 41,182,021 (+)NCBI
NHGRI_mPanPan11943,150,032 - 43,165,386 (+)NCBI
Mhudiblu_PPA_v01932,100,475 - 32,115,826 (+)NCBI
PanPan1.11940,838,920 - 40,854,027 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003816123   ⟹   XP_003816171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22041,166,684 - 41,182,021 (+)NCBI
NHGRI_mPanPan11943,150,032 - 43,165,386 (+)NCBI
Mhudiblu_PPA_v01932,100,475 - 32,115,826 (+)NCBI
PanPan1.11940,838,942 - 40,854,027 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008969207   ⟹   XP_008967455
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22041,166,684 - 41,180,201 (+)NCBI
NHGRI_mPanPan11943,150,032 - 43,162,058 (+)NCBI
Mhudiblu_PPA_v01932,100,475 - 32,112,498 (+)NCBI
PanPan1.11940,838,928 - 40,850,687 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008969208   ⟹   XP_008967456
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22041,166,684 - 41,180,201 (+)NCBI
NHGRI_mPanPan11943,150,032 - 43,162,058 (+)NCBI
Mhudiblu_PPA_v01932,100,475 - 32,112,498 (+)NCBI
PanPan1.11940,838,931 - 40,850,687 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003816170 (Get FASTA)   NCBI Sequence Viewer  
  XP_003816171 (Get FASTA)   NCBI Sequence Viewer  
  XP_008967455 (Get FASTA)   NCBI Sequence Viewer  
  XP_008967456 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035109.1
  ENSPPAP00000035113.1
RefSeq Acc Id: XP_008967455   ⟸   XM_008969207
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008967456   ⟸   XM_008969208
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003816170   ⟸   XM_003816122
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C9Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816171   ⟸   XM_003816123
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000035113   ⟸   ENSPPAT00000057999
RefSeq Acc Id: ENSPPAP00000035109   ⟸   ENSPPAT00000057995


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040354 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057995.1 UniProtKB/TrEMBL
  ENSPPAT00000057999.1 UniProtKB/TrEMBL
Gene3D-CATH Single helix bin UniProtKB/TrEMBL
InterPro FXYD_motif UniProtKB/TrEMBL
  Ion-transport_regulator_FXYD UniProtKB/TrEMBL
NCBI Gene FXYD5 ENTREZGENE
PANTHER FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 UniProtKB/TrEMBL
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/TrEMBL
Pfam ATP1G1_PLM_MAT8 UniProtKB/TrEMBL
PROSITE FXYD UniProtKB/TrEMBL
UniProt A0A2R9BZK4_PANPA UniProtKB/TrEMBL
  A0A2R9C9Q4 ENTREZGENE, UniProtKB/TrEMBL