CLSTN3 (calsyntenin 3) - Rat Genome Database

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Gene: CLSTN3 (calsyntenin 3) Pan paniscus
Analyze
Symbol: CLSTN3
Name: calsyntenin 3
RGD ID: 11969975
Description: ENCODES a protein that exhibits enzyme inhibitor activity (ortholog); INVOLVED IN adaptive thermogenesis (ortholog); cold-induced thermogenesis (ortholog); excitatory synapse assembly (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 21 (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calsyntenin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,694,523 - 12,723,611 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,691,827 - 12,720,193 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,260,361 - 7,288,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,175,951 - 7,204,526 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,175,951 - 7,204,526 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CLSTN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,694,523 - 12,723,611 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,691,827 - 12,720,193 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,260,361 - 7,288,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,175,951 - 7,204,526 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,175,951 - 7,204,526 (+)Ensemblpanpan1.1panPan2
CLSTN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38127,129,093 - 7,158,945 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl127,129,698 - 7,158,945 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,282,967 - 7,311,541 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,174,234 - 7,202,808 (+)NCBINCBI36Build 36hg18NCBI36
Build 34127,174,236 - 7,201,985NCBI
Celera128,859,131 - 8,887,704 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef127,095,705 - 7,124,262 (+)NCBIHuRef
CHM1_1127,281,942 - 7,310,507 (+)NCBICHM1_1
T2T-CHM13v2.0127,142,174 - 7,172,097 (+)NCBIT2T-CHM13v2.0
Clstn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,407,715 - 124,441,743 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,407,540 - 124,441,753 (-)EnsemblGRCm39 Ensembl
GRCm386124,430,756 - 124,464,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,430,581 - 124,464,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,380,774 - 124,414,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,396,386 - 124,430,343 (-)NCBIMGSCv36mm8
Celera6126,121,281 - 126,154,711 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.15NCBI
Clstn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,017,795 - 159,051,069 (-)NCBIGRCr8
mRatBN7.24157,331,494 - 157,364,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,331,494 - 157,364,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,554,605 - 163,588,021 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,337,510 - 159,370,931 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,982,990 - 158,016,254 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,044,736 - 157,078,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,043,925 - 157,078,130 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,064,529 - 224,097,591 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,631,047 - 160,665,193 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14160,875,982 - 160,910,129 (-)NCBI
Celera4146,072,428 - 146,105,625 (-)NCBICelera
Cytogenetic Map4q42NCBI
Clstn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,690,637 - 4,719,929 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,690,637 - 4,719,929 (+)NCBIChiLan1.0ChiLan1.0
CLSTN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,879,047 - 37,913,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,879,269 - 37,913,281 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,703,426 - 8,737,782 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,232,299 - 38,265,672 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,232,319 - 38,258,846 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,106,420 - 38,140,738 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,147,404 - 38,181,685 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,181,467 - 8,215,782 (+)NCBIUU_Cfam_GSD_1.0
Clstn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945101,963,756 - 102,005,760 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709637,641 - 673,314 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709641,615 - 673,309 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLSTN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,572,065 - 63,599,525 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,572,062 - 63,612,177 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,899,699 - 65,927,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLSTN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,197,725 - 7,226,479 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,197,539 - 7,226,651 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666063984,091 - 1,012,812 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clstn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,709,139 - 3,738,221 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,710,121 - 3,737,617 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000041330   ⟹   ENSPPAP00000018597
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl127,175,951 - 7,204,526 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000041343   ⟹   ENSPPAP00000018610
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl127,178,408 - 7,203,670 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000041354   ⟹   ENSPPAP00000018622
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl127,201,966 - 7,203,588 (+)Ensembl
RefSeq Acc Id: XM_003820254   ⟹   XP_003820302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,694,523 - 12,723,611 (+)NCBI
NHGRI_mPanPan11212,691,827 - 12,720,193 (+)NCBI
Mhudiblu_PPA_v0127,260,361 - 7,288,903 (+)NCBI
PanPan1.1127,175,951 - 7,204,526 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973652   ⟹   XP_008971900
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21012,697,610 - 12,723,611 (+)NCBI
NHGRI_mPanPan11212,694,369 - 12,720,193 (+)NCBI
Mhudiblu_PPA_v0127,262,899 - 7,288,737 (+)NCBI
PanPan1.1127,178,565 - 7,204,526 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820302 (Get FASTA)   NCBI Sequence Viewer  
  XP_008971900 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000018597
  ENSPPAP00000018597.1
  ENSPPAP00000018610
  ENSPPAP00000018610.1
  ENSPPAP00000018622.1
RefSeq Acc Id: XP_003820302   ⟸   XM_003820254
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AML8 (UniProtKB/TrEMBL),   A0A2R9AS56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008971900   ⟸   XM_008973652
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AS56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000018597   ⟸   ENSPPAT00000041330
Ensembl Acc Id: ENSPPAP00000018610   ⟸   ENSPPAT00000041343
Ensembl Acc Id: ENSPPAP00000018622   ⟸   ENSPPAT00000041354
Protein Domains
Cadherin   Calsyntenin C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041330.1 UniProtKB/TrEMBL
  ENSPPAT00000041343.1 UniProtKB/TrEMBL
  ENSPPAT00000041354.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  CLSTN_C UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100989610 UniProtKB/TrEMBL
NCBI Gene CLSTN3 ENTREZGENE
PANTHER CALSYNTENIN-3 UniProtKB/TrEMBL
  PTHR14139 UniProtKB/TrEMBL
Pfam CLSTN_C UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A2R9AML8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AMP4_PANPA UniProtKB/TrEMBL
  A0A2R9AS56 ENTREZGENE, UniProtKB/TrEMBL