TCF7 (transcription factor 7) - Rat Genome Database

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Gene: TCF7 (transcription factor 7) Pan paniscus
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Symbol: TCF7
Name: transcription factor 7
RGD ID: 11968731
Description: ENCODES a protein that exhibits beta-catenin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN alpha-beta T cell differentiation (ortholog); canonical Wnt signaling pathway (ortholog); canonical Wnt signaling pathway involved in negative regulation of apoptotic process (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH Crohn's disease (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN euchromatin (ortholog); nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: transcription factor 7; transcription factor 7 (T-cell specific, HMG-box)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15135,671,630 - 135,704,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5135,671,095 - 135,702,734 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05129,518,134 - 129,549,972 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
euchromatin  (ISO)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
TCF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15135,671,630 - 135,704,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5135,671,095 - 135,702,734 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05129,518,134 - 129,549,972 (+)NCBIMhudiblu_PPA_v0panPan3
TCF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5134,114,681 - 134,151,865 (+)EnsemblGRCh38hg38GRCh38
GRCh385134,114,681 - 134,148,229 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375133,450,372 - 133,483,901 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365133,478,301 - 133,511,819 (+)NCBINCBI36hg18NCBI36
Celera5129,574,095 - 129,607,613 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5128,635,317 - 128,668,890 (+)NCBIHuRef
CHM1_15132,882,980 - 132,916,497 (+)NCBICHM1_1
Tcf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,137,347 - 52,174,211 (-)NCBIGRCm39mm39
GRCm39 Ensembl1152,143,198 - 52,174,158 (-)Ensembl
GRCm381152,246,527 - 52,283,383 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,252,371 - 52,283,331 (-)EnsemblGRCm38mm10GRCm38
MGSCv371152,066,106 - 52,096,073 (-)NCBIGRCm37mm9NCBIm37
MGSCv361152,096,027 - 52,125,994 (-)NCBImm8
Celera1156,821,774 - 56,852,195 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.86NCBI
Tcf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21036,423,443 - 36,454,350 (-)NCBI
Rnor_6.0 Ensembl1037,617,279 - 37,645,802 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01037,616,033 - 37,646,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01037,389,506 - 37,419,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,686,862 - 37,716,831 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11037,693,621 - 37,723,030 (-)NCBI
Celera1035,778,033 - 35,807,975 (-)NCBICelera
Cytogenetic Map10q22NCBI
Tcf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554085,362,084 - 5,388,527 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554085,362,423 - 5,388,684 (+)NCBIChiLan1.0ChiLan1.0
TCF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,313,113 - 22,346,221 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,313,105 - 22,344,004 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,059,022 - 21,092,131 (+)NCBI
ROS_Cfam_1.01123,113,932 - 23,147,114 (+)NCBI
UMICH_Zoey_3.11121,814,042 - 21,847,134 (+)NCBI
UNSW_CanFamBas_1.01121,679,173 - 21,712,308 (+)NCBI
UU_Cfam_GSD_1.01122,321,753 - 22,354,875 (+)NCBI
Tcf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213114,092,704 - 114,122,991 (-)NCBI
SpeTri2.0NW_0049366471,096,726 - 1,125,753 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,422,712 - 136,458,037 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12136,422,740 - 136,456,323 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,042,088 - 142,051,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCF7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12336,919,648 - 36,953,088 (+)NCBI
ChlSab1.1 Ensembl2336,919,745 - 36,951,192 (+)Ensembl
Vero_WHO_p1.0NW_02366603440,979,669 - 41,016,821 (-)NCBI
Tcf7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473338,076,800 - 38,104,265 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034960507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000045162   ⟹   ENSPPAP00000022352
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5135,671,095 - 135,702,734 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045168   ⟹   ENSPPAP00000022358
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5135,671,885 - 135,702,398 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045174   ⟹   ENSPPAP00000022364
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5135,672,198 - 135,702,516 (+)Ensembl
RefSeq Acc Id: XM_034960507   ⟹   XP_034816398
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v05129,518,134 - 129,549,972 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034816398 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034816398   ⟸   XM_034960507
RefSeq Acc Id: ENSPPAP00000022364   ⟸   ENSPPAT00000045174
RefSeq Acc Id: ENSPPAP00000022352   ⟸   ENSPPAT00000045162
RefSeq Acc Id: ENSPPAP00000022358   ⟸   ENSPPAT00000045168
Protein Domains
HMG box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034368 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022352 UniProtKB/TrEMBL
  ENSPPAP00000022358 UniProtKB/TrEMBL
  ENSPPAP00000022364 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045162 UniProtKB/TrEMBL
  ENSPPAT00000045168 UniProtKB/TrEMBL
  ENSPPAT00000045174 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro CTNNB1-bd_N UniProtKB/TrEMBL
  HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  TCF/LEF UniProtKB/TrEMBL
  Tcf7 UniProtKB/TrEMBL
NCBI Gene TCF7 ENTREZGENE
PANTHER PTHR10373 UniProtKB/TrEMBL
  PTHR10373:SF33 UniProtKB/TrEMBL
Pfam CTNNB1_binding UniProtKB/TrEMBL
  HMG_box UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A2R9AYH7_PANPA UniProtKB/TrEMBL
  A0A2R9AZ57_PANPA UniProtKB/TrEMBL
  A0A2R9B2H3_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 TCF7  transcription factor 7    transcription factor 7 (T-cell specific, HMG-box)  Symbol and/or name change 5135510 APPROVED